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The map label for this gene is pheS [H]

Identifier: 91787979

GI number: 91787979

Start: 2194580

End: 2195644

Strand: Direct

Name: pheS [H]

Synonym: Bpro_2106

Alternate gene names: 91787979

Gene position: 2194580-2195644 (Clockwise)

Preceding gene: 91787978

Following gene: 91787980

Centisome position: 42.2

GC content: 61.88

Gene sequence:

>1065_bases
ATGAATCATCCTGATGCCCTCCACGAACTGGTCAGCAGCGCCCAAGCCAGTTTTGCGCAGGCCACCACGCCCGCCGACCT
GGAAAACGCCAAGGCGCAGTTTCTCGGTAAATCGGGCCGCGTCACCGAGTTGATGAAAGGCATGGCCGCCCTCAGCGTGG
AAGAAAAGAAATCCCGCGGTGCCGCCATCAACCTGGCCAAGCAGGCCATTGAAGCGGCTCTCAATGATCGCCGGCAAGCG
CTCGCCAACGCCGAACTCGAAAAGCAGCTCAAGGCTGAAGCCTTGGACGTGAGCCTGCCGGGCCGCCAGCGCGCACAGGG
CGGGCTGCATCCGGTGTCGCTCACGCTCGAGCGCATCGAGGCCATTTTTGGCTCCATGGGGTTTGACGTGGCGCAGGGCC
CGGAGATTGAGACCGACTGGTTCAATTTCACCGCACTCAACACGCCGGAAGATCATCCGGCGCGCTCCATGCACGACACG
TTTTATGTCGAAGGCGGCACCGAAGCCGCGCCCAATTTGTTGCGTACCCACACCAGCCCCATGCAGATCCGCTATGCGGT
CCAGCATGTCAAGAAGCACCGCGCGCTCATTGACGCGGGCGGCCGGATGCCGGAGATTCGTGTCATTGCGCCGGGCCGCA
CCTACCGCGTGGACAGCGACGCCACGCATTCGCCGATGTTCCACCAGTGCGAAGGCCTGTGGATCGGCGAAAACGTGAGC
TTCAAGGACCTGAAGTTCGTGTTCACCGATTTTTGCCGCACCTTCTTTGAGAGCAACGACCTGGTGCTGCGCTTTCGCCC
CAGCTTTTTCCCGTTCACCGAACCCAGCGCTGAAATCGACATCCAGTTCCAGACAGGCCCGCTGGCCGGCCGCTGGCTGG
AAGTGGCCGGCTCCGGCCAGGTGCACCCGAACGTGGTGCGCAACATGGGGCTGGATCCCGAGAAATACATCGGCTTTGCC
TTTGGCATGGGCCCGGACCGCCTGACCATGCTGCGCTACGGTGTGAATGACCTGCGCCTGTTCTTTGACGGCGACATCCG
CTTCCTGTCCCAGTTCCAGTCATAA

Upstream 100 bases:

>100_bases
CGGGTTCAGGGATTGGCCGGTCTGCTTGACCGGTTGCCCGCCTGGTGAGAGTGTTGTTGAAAACGCCTGAGCTGTTTCCT
TAAGTCGAACAAGAGAATGT

Downstream 100 bases:

>100_bases
CAACAAGAAAAAGAACAAGGTAAGACCATGCAATTCCCAGAATCCTGGTTGCGCGAATTCTGCAATCCGCCGCTCAATAC
CCAGCAGCTCGCTGAAACCC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNHPDALHELVSSAQASFAQATTPADLENAKAQFLGKSGRVTELMKGMAALSVEEKKSRGAAINLAKQAIEAALNDRRQA
LANAELEKQLKAEALDVSLPGRQRAQGGLHPVSLTLERIEAIFGSMGFDVAQGPEIETDWFNFTALNTPEDHPARSMHDT
FYVEGGTEAAPNLLRTHTSPMQIRYAVQHVKKHRALIDAGGRMPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWIGENVS
FKDLKFVFTDFCRTFFESNDLVLRFRPSFFPFTEPSAEIDIQFQTGPLAGRWLEVAGSGQVHPNVVRNMGLDPEKYIGFA
FGMGPDRLTMLRYGVNDLRLFFDGDIRFLSQFQS

Sequences:

>Translated_354_residues
MNHPDALHELVSSAQASFAQATTPADLENAKAQFLGKSGRVTELMKGMAALSVEEKKSRGAAINLAKQAIEAALNDRRQA
LANAELEKQLKAEALDVSLPGRQRAQGGLHPVSLTLERIEAIFGSMGFDVAQGPEIETDWFNFTALNTPEDHPARSMHDT
FYVEGGTEAAPNLLRTHTSPMQIRYAVQHVKKHRALIDAGGRMPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWIGENVS
FKDLKFVFTDFCRTFFESNDLVLRFRPSFFPFTEPSAEIDIQFQTGPLAGRWLEVAGSGQVHPNVVRNMGLDPEKYIGFA
FGMGPDRLTMLRYGVNDLRLFFDGDIRFLSQFQS
>Mature_354_residues
MNHPDALHELVSSAQASFAQATTPADLENAKAQFLGKSGRVTELMKGMAALSVEEKKSRGAAINLAKQAIEAALNDRRQA
LANAELEKQLKAEALDVSLPGRQRAQGGLHPVSLTLERIEAIFGSMGFDVAQGPEIETDWFNFTALNTPEDHPARSMHDT
FYVEGGTEAAPNLLRTHTSPMQIRYAVQHVKKHRALIDAGGRMPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWIGENVS
FKDLKFVFTDFCRTFFESNDLVLRFRPSFFPFTEPSAEIDIQFQTGPLAGRWLEVAGSGQVHPNVVRNMGLDPEKYIGFA
FGMGPDRLTMLRYGVNDLRLFFDGDIRFLSQFQS

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=271, Percent_Identity=31.3653136531365, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI5729820, Length=297, Percent_Identity=30.976430976431, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI1788007, Length=347, Percent_Identity=53.314121037464, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI32563657, Length=278, Percent_Identity=31.6546762589928, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17508957, Length=278, Percent_Identity=31.6546762589928, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32566635, Length=261, Percent_Identity=32.5670498084291, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321087, Length=372, Percent_Identity=27.4193548387097, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6325304, Length=93, Percent_Identity=39.7849462365591, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI18858079, Length=297, Percent_Identity=30.6397306397306, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17137424, Length=301, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 39373; Mature: 39373

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPDALHELVSSAQASFAQATTPADLENAKAQFLGKSGRVTELMKGMAALSVEEKKSRG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
AAINLAKQAIEAALNDRRQALANAELEKQLKAEALDVSLPGRQRAQGGLHPVSLTLERIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCHHHHHHHHHH
AIFGSMGFDVAQGPEIETDWFNFTALNTPEDHPARSMHDTFYVEGGTEAAPNLLRTHTSP
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCC
MQIRYAVQHVKKHRALIDAGGRMPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWIGENVS
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCHHHHCCCEEECCCCC
FKDLKFVFTDFCRTFFESNDLVLRFRPSFFPFTEPSAEIDIQFQTGPLAGRWLEVAGSGQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCC
VHPNVVRNMGLDPEKYIGFAFGMGPDRLTMLRYGVNDLRLFFDGDIRFLSQFQS
CCHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHCCCEEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MNHPDALHELVSSAQASFAQATTPADLENAKAQFLGKSGRVTELMKGMAALSVEEKKSRG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
AAINLAKQAIEAALNDRRQALANAELEKQLKAEALDVSLPGRQRAQGGLHPVSLTLERIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCHHHHHHHHHH
AIFGSMGFDVAQGPEIETDWFNFTALNTPEDHPARSMHDTFYVEGGTEAAPNLLRTHTSP
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCC
MQIRYAVQHVKKHRALIDAGGRMPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWIGENVS
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCHHHHCCCEEECCCCC
FKDLKFVFTDFCRTFFESNDLVLRFRPSFFPFTEPSAEIDIQFQTGPLAGRWLEVAGSGQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCC
VHPNVVRNMGLDPEKYIGFAFGMGPDRLTMLRYGVNDLRLFFDGDIRFLSQFQS
CCHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHCCCEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA