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The map label for this gene is echA8 [H]

Identifier: 91787966

GI number: 91787966

Start: 2180288

End: 2181157

Strand: Direct

Name: echA8 [H]

Synonym: Bpro_2093

Alternate gene names: 91787966

Gene position: 2180288-2181157 (Clockwise)

Preceding gene: 91787965

Following gene: 91787967

Centisome position: 41.93

GC content: 62.64

Gene sequence:

>870_bases
ATGAGCGGCGCCATTTTGCTGGAAAGGCTGGGCCCGGTTGCGACAGTAACCCTGTCGCACCCTGGCAAGCTCAATGCCAT
GTCGCGAGCGATGTGGCGTGAGTTGCGGACTGCGTTCGAGCAGCTCCAGTGCGGTGGCGACGTGACCTGCGTGCTGGTAC
GCGGCGACCGTGCGCCCGCCAGCGCAGAGGGTGTCGGCCACTTTTGCGCCGGGGGCGATATCTCCGAATATGCTGATTTC
CGCTTCGACGAAGCCAGCTTGCGCAACTTCCATGAAAACGAGGTCTGGGGCGGCCTGCAGGCGATGCTTGACTGCGACAT
TCCCATCGTTGCCCAGATCGAGGGCAACTGCATGGGGGCCGGCATGGAGATCGCCAGTTGCTGCGACATCCGCATTGCCA
GCGAGACGGCCCGTTTTGGTGCGCCAATTGCCAAACTGGGCTTTCCCATGGCCCCGCGCGAGGCGGCGTTGGTGATGCGC
GCTGCCGGCGAGCTGACGGCACGTGAAATGCTGCTGTCGGCAGCGGTGCTGGACGCGGCTGAGATGAAGCAGCGCGGTTT
TCTCAGCCAGGTCGTGCCGGCGGGTGAGGTCGCCCATGCGGCGCTGGCGTATGCGGGCCGCATCAGCCAGCTGGCTCCTC
AGGCGGCGCGTCTGAACAAGCAGACTTTCAGGGCGTTGACTCCCAGCCTCGCTGCGCAACCCATTGCAGAATTAATAGCG
GGCGCCTATGACTACGCGAACGCAGCCGAACACCGCGAGGGCGTGATGGCCTTTGTTGAAAAACGCCAGCCCCGTTTTTG
TCAGCCCCGTTTAATGGCTGCACTTTCCGAATTCCCAACCTTCGACAGCCCGATCCATGAAAAACCATAA

Upstream 100 bases:

>100_bases
CCACGCTTTTCACTTCGTGTAATGCGCTGCCCCCCGAGGGGGCTAATTTTCCTAGGGGCTGCCCGTCGGAAAATTGCATA
CTTCCCACACTTTTCATACG

Downstream 100 bases:

>100_bases
CCTGTTTGCGGCACTGCGTGCCGCCTTTCCTGCCTCGCTGGATGACGTCGCCGTTGAAACCGACCATGGCCTGTTCTATA
CATGGCGCGACCTCGACCGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSGAILLERLGPVATVTLSHPGKLNAMSRAMWRELRTAFEQLQCGGDVTCVLVRGDRAPASAEGVGHFCAGGDISEYADF
RFDEASLRNFHENEVWGGLQAMLDCDIPIVAQIEGNCMGAGMEIASCCDIRIASETARFGAPIAKLGFPMAPREAALVMR
AAGELTAREMLLSAAVLDAAEMKQRGFLSQVVPAGEVAHAALAYAGRISQLAPQAARLNKQTFRALTPSLAAQPIAELIA
GAYDYANAAEHREGVMAFVEKRQPRFCQPRLMAALSEFPTFDSPIHEKP

Sequences:

>Translated_289_residues
MSGAILLERLGPVATVTLSHPGKLNAMSRAMWRELRTAFEQLQCGGDVTCVLVRGDRAPASAEGVGHFCAGGDISEYADF
RFDEASLRNFHENEVWGGLQAMLDCDIPIVAQIEGNCMGAGMEIASCCDIRIASETARFGAPIAKLGFPMAPREAALVMR
AAGELTAREMLLSAAVLDAAEMKQRGFLSQVVPAGEVAHAALAYAGRISQLAPQAARLNKQTFRALTPSLAAQPIAELIA
GAYDYANAAEHREGVMAFVEKRQPRFCQPRLMAALSEFPTFDSPIHEKP
>Mature_288_residues
SGAILLERLGPVATVTLSHPGKLNAMSRAMWRELRTAFEQLQCGGDVTCVLVRGDRAPASAEGVGHFCAGGDISEYADFR
FDEASLRNFHENEVWGGLQAMLDCDIPIVAQIEGNCMGAGMEIASCCDIRIASETARFGAPIAKLGFPMAPREAALVMRA
AGELTAREMLLSAAVLDAAEMKQRGFLSQVVPAGEVAHAALAYAGRISQLAPQAARLNKQTFRALTPSLAAQPIAELIAG
AYDYANAAEHREGVMAFVEKRQPRFCQPRLMAALSEFPTFDSPIHEKP

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=259, Percent_Identity=26.6409266409266, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI194097323, Length=269, Percent_Identity=27.5092936802974, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502327, Length=246, Percent_Identity=27.2357723577236, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787659, Length=268, Percent_Identity=29.1044776119403, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082183, Length=263, Percent_Identity=26.9961977186312, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=25.2873563218391, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=269, Percent_Identity=29.368029739777, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25145438, Length=267, Percent_Identity=28.0898876404494, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=228, Percent_Identity=27.1929824561404, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=229, Percent_Identity=26.6375545851528, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=273, Percent_Identity=24.5421245421245, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=225, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=210, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=254, Percent_Identity=26.3779527559055, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=23.8461538461538, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=26.3779527559055, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=26.3779527559055, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653139, Length=272, Percent_Identity=27.9411764705882, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19920382, Length=219, Percent_Identity=25.1141552511416, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 31006; Mature: 30875

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAILLERLGPVATVTLSHPGKLNAMSRAMWRELRTAFEQLQCGGDVTCVLVRGDRAPA
CCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
SAEGVGHFCAGGDISEYADFRFDEASLRNFHENEVWGGLQAMLDCDIPIVAQIEGNCMGA
CCCCCCCCCCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GMEIASCCDIRIASETARFGAPIAKLGFPMAPREAALVMRAAGELTAREMLLSAAVLDAA
CCHHHHHHCEEECCHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMKQRGFLSQVVPAGEVAHAALAYAGRISQLAPQAARLNKQTFRALTPSLAAQPIAELIA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
GAYDYANAAEHREGVMAFVEKRQPRFCQPRLMAALSEFPTFDSPIHEKP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SGAILLERLGPVATVTLSHPGKLNAMSRAMWRELRTAFEQLQCGGDVTCVLVRGDRAPA
CCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
SAEGVGHFCAGGDISEYADFRFDEASLRNFHENEVWGGLQAMLDCDIPIVAQIEGNCMGA
CCCCCCCCCCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GMEIASCCDIRIASETARFGAPIAKLGFPMAPREAALVMRAAGELTAREMLLSAAVLDAA
CCHHHHHHCEEECCHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMKQRGFLSQVVPAGEVAHAALAYAGRISQLAPQAARLNKQTFRALTPSLAAQPIAELIA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
GAYDYANAAEHREGVMAFVEKRQPRFCQPRLMAALSEFPTFDSPIHEKP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]