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The map label for this gene is clpX [H]

Identifier: 91787907

GI number: 91787907

Start: 2104798

End: 2106063

Strand: Direct

Name: clpX [H]

Synonym: Bpro_2031

Alternate gene names: 91787907

Gene position: 2104798-2106063 (Clockwise)

Preceding gene: 91787906

Following gene: 91787908

Centisome position: 40.47

GC content: 57.11

Gene sequence:

>1266_bases
ATGGCCGAGAAAAAAGGCTCCTCCGGCGAAAAGACTCTGTACTGCTCCTTCTGCGGCAAGAGTCAGCACGAAGTTAAAAA
ACTGATCGCCGGTCCCTCGGTCTTTATCTGTGACGAGTGCATCGATCTTTGCAACGAGATCATCCGTGACGAGTTGCCCG
CCGGCGAAGATGTCCGCGAAACGCGCACCGATTTGCCGACGCCGGCAGAAATCAAGGCGACACTGGACGGCTACGTGATT
GGCCAGGAACCAGCCAAGCGCACGCTGGCCGTGGCTGTCTACAACCACTACAAGCGCCTGCGCCACAAGGAAAAAGCCAA
AAAAGACGATGTGGAGCTGACGAAAAGCAATATTTTGCTGATCGGCCCCACGGGCTCCGGCAAGACCCTGCTGGCCCAAA
CGCTGGCACGCACGCTCAACGTTCCATTCGTCATGGCCGATGCCACCACGCTGACGGAAGCGGGTTATGTTGGTGAAGAC
GTTGAAAACATCATCCAGAAATTGCTGCAAAGCTGCAATTACGAGGTTGAGCGCGCCCAGCAGGGCATCGTCTACATCGA
CGAGATCGACAAGATCTCGCGCAAATCCGACAATCCTTCCATCACCCGTGACGTATCGGGCGAGGGAGTGCAACAGGCTT
TGCTCAAGCTGATTGAAGGCACCATGGCTTCGGTGCCACCGCAGGGCGGGCGCAAGCACCCCAACCAGGATTTCCTGCAG
GTCGACACGACCAATATCCTGTTTATCTGTGGGGGTGCGTTCTCCGGGCTGGAAAAAGTCATTGAGAACCGTACTGAGGC
CTCGGGTATTGGCTTTGGCGCCTTGGTTAAAAGCAAAAAGACCCGTTCGCTGACGGAGTCGTTCAAGGAAGTCGAACCGG
AAGACCTGATCAAGTTCGGCCTGATTCCCGAACTGGTGGGCCGCATGCCGGTTGTTGCGACGCTGGCGGAACTCACGGAA
GATGCCCTCGTGCAAATCCTGACCGAGCCGAAAAATGCCGTGGTCAAGCAGTTCAGCAAGCTGCTCTCCATGGAGGGGGT
GGACCTGGAAATCCGGCCCTCCGCGCTCAAGGCCATTGCCCGCAAGGCCCTGGCCCGCAAGACGGGAGCGCGGGGCCTGC
GCTCCATCCTCGAGCAGTCACTGATTGACACCATGTTTGACTTGCCCAATGCCAGTAATGTCGACAAGGTTGTGGTGGAC
GAGTCGACAATCGAGGAAAACAAGGCACCGTTGCTCGTGTACCGCGAAACTGCCAAGAAAGCCTGA

Upstream 100 bases:

>100_bases
TTTTCTGTAACTGAAACGCCGTTTTTTTATTGGTTATCATTAGGTAACACTTTCCTCTAACCCCCTAGCTCTTCTAGCCA
TCTTTAAAGGCATCCCATCA

Downstream 100 bases:

>100_bases
TCCGGAAAGGGGCGGGCGCAAGGCTTGAAAAGCAATTCTTGCGCCCCACTTCTGGGTTGACTACGCTACTCCTGGCCATG
AAACTGGTCGCCACGGCTTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAEKKGSSGEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPAGEDVRETRTDLPTPAEIKATLDGYVI
GQEPAKRTLAVAVYNHYKRLRHKEKAKKDDVELTKSNILLIGPTGSGKTLLAQTLARTLNVPFVMADATTLTEAGYVGED
VENIIQKLLQSCNYEVERAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFSGLEKVIENRTEASGIGFGALVKSKKTRSLTESFKEVEPEDLIKFGLIPELVGRMPVVATLAELTE
DALVQILTEPKNAVVKQFSKLLSMEGVDLEIRPSALKAIARKALARKTGARGLRSILEQSLIDTMFDLPNASNVDKVVVD
ESTIEENKAPLLVYRETAKKA

Sequences:

>Translated_421_residues
MAEKKGSSGEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPAGEDVRETRTDLPTPAEIKATLDGYVI
GQEPAKRTLAVAVYNHYKRLRHKEKAKKDDVELTKSNILLIGPTGSGKTLLAQTLARTLNVPFVMADATTLTEAGYVGED
VENIIQKLLQSCNYEVERAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFSGLEKVIENRTEASGIGFGALVKSKKTRSLTESFKEVEPEDLIKFGLIPELVGRMPVVATLAELTE
DALVQILTEPKNAVVKQFSKLLSMEGVDLEIRPSALKAIARKALARKTGARGLRSILEQSLIDTMFDLPNASNVDKVVVD
ESTIEENKAPLLVYRETAKKA
>Mature_420_residues
AEKKGSSGEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPAGEDVRETRTDLPTPAEIKATLDGYVIG
QEPAKRTLAVAVYNHYKRLRHKEKAKKDDVELTKSNILLIGPTGSGKTLLAQTLARTLNVPFVMADATTLTEAGYVGEDV
ENIIQKLLQSCNYEVERAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQV
DTTNILFICGGAFSGLEKVIENRTEASGIGFGALVKSKKTRSLTESFKEVEPEDLIKFGLIPELVGRMPVVATLAELTED
ALVQILTEPKNAVVKQFSKLLSMEGVDLEIRPSALKAIARKALARKTGARGLRSILEQSLIDTMFDLPNASNVDKVVVDE
STIEENKAPLLVYRETAKKA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=329, Percent_Identity=52.2796352583587, Blast_Score=317, Evalue=2e-86,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=71.875, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1790366, Length=102, Percent_Identity=47.0588235294118, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=46.3022508038585, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=46.3022508038585, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=423, Percent_Identity=37.1158392434988, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=264, Percent_Identity=40.530303030303, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=38.5514018691589, Blast_Score=272, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=47.4842767295598, Blast_Score=289, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=47.4842767295598, Blast_Score=288, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46072; Mature: 45940

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKGSSGEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPAGEDVRE
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHH
TRTDLPTPAEIKATLDGYVIGQEPAKRTLAVAVYNHYKRLRHKEKAKKDDVELTKSNILL
HHCCCCCCHHHEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCEECCCEEE
IGPTGSGKTLLAQTLARTLNVPFVMADATTLTEAGYVGEDVENIIQKLLQSCNYEVERAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
QGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCCEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFSGLEKVIENRTEASGIGFGALVKSKKTRSLTESFKEVEPEDLIKFG
EECCEEEEEECCHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
LIPELVGRMPVVATLAELTEDALVQILTEPKNAVVKQFSKLLSMEGVDLEIRPSALKAIA
CHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
RKALARKTGARGLRSILEQSLIDTMFDLPNASNVDKVVVDESTIEENKAPLLVYRETAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCCCEEEEECCCCC
A
C
>Mature Secondary Structure 
AEKKGSSGEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPAGEDVRE
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHH
TRTDLPTPAEIKATLDGYVIGQEPAKRTLAVAVYNHYKRLRHKEKAKKDDVELTKSNILL
HHCCCCCCHHHEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCEECCCEEE
IGPTGSGKTLLAQTLARTLNVPFVMADATTLTEAGYVGEDVENIIQKLLQSCNYEVERAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
QGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCCEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFSGLEKVIENRTEASGIGFGALVKSKKTRSLTESFKEVEPEDLIKFG
EECCEEEEEECCHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
LIPELVGRMPVVATLAELTEDALVQILTEPKNAVVKQFSKLLSMEGVDLEIRPSALKAIA
CHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
RKALARKTGARGLRSILEQSLIDTMFDLPNASNVDKVVVDESTIEENKAPLLVYRETAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCCCEEEEECCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA