Click here to switch to the map view.

The map label for this gene is tig [H]

Identifier: 91787905

GI number: 91787905

Start: 2102593

End: 2103903

Strand: Direct

Name: tig [H]

Synonym: Bpro_2029

Alternate gene names: 91787905

Gene position: 2102593-2103903 (Clockwise)

Preceding gene: 91787904

Following gene: 91787906

Centisome position: 40.43

GC content: 60.41

Gene sequence:

>1311_bases
ATGGCCGTGACTGTTGAAACCCTTGAAAAGCTTGAGCGCAAAATGACGCTGACGCTGCCCCTCAATACCATTCAGTCGGA
AGTCGATACGCGCCTGAAGCGCTTGGCCCGCACGGTGAAGATGGACGGCTTTCGTCCCGGCAAGGTGCCCATGAATGTGG
TGGCCCAGCGTTACGGCTACTCGGTGCACTATGAAGTCATGAACGACAAGGTGGGCGAGGCTTTTGCCGTGGCAGCCAAC
GAAGCCAAGCTGCGTGTTGCCGGCCAGCCCCGCATCAGCGAAAAAGAGGGTGCCCCTGAAGGCGAGCTGGTCTTTGACGC
CGTCTTCGAGGTCTATCCCGACGTCAAGATTGCCGACCTGACCCAGGCAGAAGTCGAAAAGGTCAGCGCTGAAGTCAGCG
ATGCAGCCATCGACAAGACTGTGGACATCCTGCGCAAGCAGCGCCGCACGTTCGCGCAGCGCGCTGCCGATGCGCCGGCC
CAGGACGGCGACCGCGCCACCATCGACTTCGAAGGCAAGATCGACGGCGAAACCTTTGCCGGGGGCAAGGCGGAAGATTT
CCAGTTCCTGGTCGGTGAAGGCCAGATGCTCAAGGAATTTGAAGATGCCGTGCGCGGCATGAAAAGCGGCGAGAGCAAGA
CTTTCCCGCTGAACTTCCCGGCTGACTACCACGGCAAGGACGTTGCCGGCAAGCAGGCGGACTTTCTGGTGACGGTCAAG
AAAATCGAAGCAGCTCACCTGCCCGAAGTCAACGAGGCACTGGCCAAGTCGCTGGGCATCGCGGATGGGACCGTGGAAGC
CCTGCGCGCCGACATCAAGAAAAACCTCGAGCGTGAAGTCAAGTTCCGCTTGCTGGCCCGCAACAAAAACGCCGTGATGG
ACGCGCTGGTGGCCAATGCCGAACTCGAGCTGCCAAAATCCAGCGTTCAGGCCGAAGTCGACCGCATGATCGAAGGCGCG
CGCGCCGACCTGAAGCAGCGCGGCATCAAGGACGCCGACAAGGCACCAATTCCTGACGACGTCTTCCGTCCCCAGGCTGA
AAAGCGCGTGCGCCTGGGCCTGGTGGTGGCCGAACTGGTTCGTGCCAACGGCCTGCAGGCCAAACCCGAGCAGCTCAAGG
CCCATATTGAGGAATTGGCTGCCAGCTACGAAAAGCCCCAGGACGTGGTGCGCTGGTACCTTGGCGACAACCGCCGCATG
GCTGAAGTGGAAGCGGTTGTCATCGAGAACAACGTGACGGAGTTTGTCCTGGGTAAGGCCAAAGTCAACGACAAGGCCAT
CTCTTTCGACGACCTGATGGGCCAGAACTGA

Upstream 100 bases:

>100_bases
CAGGTGAAGTGCTGCTTCCGGGCCTTCAGGCTTTGCGGCATTGCCGCAGCATGTCAGGTGCAAGCCCTGTTTTGAATATT
TTTGATCTTAGGAAACCATC

Downstream 100 bases:

>100_bases
CAGGGCGAAATTTCTCCTGAAGCTGGGGCTTGTGCCTGACTTGAAGTCGGGGGCACAGGCCCCAATTTATTTTAGGTACA
GTACAAACATCTCTGGAGAA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MAVTVETLEKLERKMTLTLPLNTIQSEVDTRLKRLARTVKMDGFRPGKVPMNVVAQRYGYSVHYEVMNDKVGEAFAVAAN
EAKLRVAGQPRISEKEGAPEGELVFDAVFEVYPDVKIADLTQAEVEKVSAEVSDAAIDKTVDILRKQRRTFAQRAADAPA
QDGDRATIDFEGKIDGETFAGGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLNFPADYHGKDVAGKQADFLVTVK
KIEAAHLPEVNEALAKSLGIADGTVEALRADIKKNLEREVKFRLLARNKNAVMDALVANAELELPKSSVQAEVDRMIEGA
RADLKQRGIKDADKAPIPDDVFRPQAEKRVRLGLVVAELVRANGLQAKPEQLKAHIEELAASYEKPQDVVRWYLGDNRRM
AEVEAVVIENNVTEFVLGKAKVNDKAISFDDLMGQN

Sequences:

>Translated_436_residues
MAVTVETLEKLERKMTLTLPLNTIQSEVDTRLKRLARTVKMDGFRPGKVPMNVVAQRYGYSVHYEVMNDKVGEAFAVAAN
EAKLRVAGQPRISEKEGAPEGELVFDAVFEVYPDVKIADLTQAEVEKVSAEVSDAAIDKTVDILRKQRRTFAQRAADAPA
QDGDRATIDFEGKIDGETFAGGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLNFPADYHGKDVAGKQADFLVTVK
KIEAAHLPEVNEALAKSLGIADGTVEALRADIKKNLEREVKFRLLARNKNAVMDALVANAELELPKSSVQAEVDRMIEGA
RADLKQRGIKDADKAPIPDDVFRPQAEKRVRLGLVVAELVRANGLQAKPEQLKAHIEELAASYEKPQDVVRWYLGDNRRM
AEVEAVVIENNVTEFVLGKAKVNDKAISFDDLMGQN
>Mature_435_residues
AVTVETLEKLERKMTLTLPLNTIQSEVDTRLKRLARTVKMDGFRPGKVPMNVVAQRYGYSVHYEVMNDKVGEAFAVAANE
AKLRVAGQPRISEKEGAPEGELVFDAVFEVYPDVKIADLTQAEVEKVSAEVSDAAIDKTVDILRKQRRTFAQRAADAPAQ
DGDRATIDFEGKIDGETFAGGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLNFPADYHGKDVAGKQADFLVTVKK
IEAAHLPEVNEALAKSLGIADGTVEALRADIKKNLEREVKFRLLARNKNAVMDALVANAELELPKSSVQAEVDRMIEGAR
ADLKQRGIKDADKAPIPDDVFRPQAEKRVRLGLVVAELVRANGLQAKPEQLKAHIEELAASYEKPQDVVRWYLGDNRRMA
EVEAVVIENNVTEFVLGKAKVNDKAISFDDLMGQN

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=436, Percent_Identity=39.2201834862385, Blast_Score=320, Evalue=1e-88,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 48150; Mature: 48019

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTVETLEKLERKMTLTLPLNTIQSEVDTRLKRLARTVKMDGFRPGKVPMNVVAQRYGY
CEEEHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
SVHYEVMNDKVGEAFAVAANEAKLRVAGQPRISEKEGAPEGELVFDAVFEVYPDVKIADL
EEEEEECCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECC
TQAEVEKVSAEVSDAAIDKTVDILRKQRRTFAQRAADAPAQDGDRATIDFEGKIDGETFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCC
GGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLNFPADYHGKDVAGKQADFLVTVK
CCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEHH
KIEAAHLPEVNEALAKSLGIADGTVEALRADIKKNLEREVKFRLLARNKNAVMDALVANA
HHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
ELELPKSSVQAEVDRMIEGARADLKQRGIKDADKAPIPDDVFRPQAEKRVRLGLVVAELV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
RANGLQAKPEQLKAHIEELAASYEKPQDVVRWYLGDNRRMAEVEAVVIENNVTEFVLGKA
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHEEEEEEECCCHHHHCCCC
KVNDKAISFDDLMGQN
CCCCCCCCHHHHCCCC
>Mature Secondary Structure 
AVTVETLEKLERKMTLTLPLNTIQSEVDTRLKRLARTVKMDGFRPGKVPMNVVAQRYGY
EEEHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
SVHYEVMNDKVGEAFAVAANEAKLRVAGQPRISEKEGAPEGELVFDAVFEVYPDVKIADL
EEEEEECCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECC
TQAEVEKVSAEVSDAAIDKTVDILRKQRRTFAQRAADAPAQDGDRATIDFEGKIDGETFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCC
GGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLNFPADYHGKDVAGKQADFLVTVK
CCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEHH
KIEAAHLPEVNEALAKSLGIADGTVEALRADIKKNLEREVKFRLLARNKNAVMDALVANA
HHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
ELELPKSSVQAEVDRMIEGARADLKQRGIKDADKAPIPDDVFRPQAEKRVRLGLVVAELV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
RANGLQAKPEQLKAHIEELAASYEKPQDVVRWYLGDNRRMAEVEAVVIENNVTEFVLGKA
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHEEEEEEECCCHHHHCCCC
KVNDKAISFDDLMGQN
CCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA