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The map label for this gene is mdtA [H]

Identifier: 91787903

GI number: 91787903

Start: 2097817

End: 2098989

Strand: Direct

Name: mdtA [H]

Synonym: Bpro_2027

Alternate gene names: 91787903

Gene position: 2097817-2098989 (Clockwise)

Preceding gene: 91787902

Following gene: 91787904

Centisome position: 40.34

GC content: 64.96

Gene sequence:

>1173_bases
ATGAAAAAAACCGTCTTTTCGCTGGTGAGTATCGCTGCCTTGCTGGCCGCCTGTACCCCATCCGCTCCGCCTGAAGAGCC
GGTTCGCGCCGTGAAGGTGATGACTGTGGGGACTGATGCGTTTTCTTCCAGTCATGAATATGCGGGTGAAGTCAGGGCCC
GGGTCGAGTCCCGCCTGGGTTTCAGGGTCGGGGGCAAGATCATCAAGCGGCAGGCCGAGCTGGGCCAACGCGTCAAGGCC
GGCCAGGTGCTGGCCCAACTGGACCCGCAGGATTACAAGCTGGCCGTCGACGCGGCCCGCGCCCAGGTTGCAACGGCGAT
GACCAACCGGGATCTCGCCGCGGCTGATTTCAAGCGCTACAAAGAGCTGAAGGACCAGAGTTTCATCAGTGGCGCGGAAC
TGGAGCGTCGCGAAACGACCTTCAAGGCGGCCCAGGCGCAACTCGAGCAGGCCCAGTCGCAGCTGGCCGTGCAGAGCAAC
CAGGCCGGTTATGCCGCGCTGGTGGCCGACGTCTCGGGTGTGGTGACCGCGGTGGAGGCCGAGCCGGGTCAGGTGGTAGC
CGCCGGGGTGCCGGTGGTGCGCATTGCGGCCGACGGCGTGCGTGACGTGGTGTTCTCGGTGCCCGAAGACCGGGTGGCCG
GCATCAAGGTCGGTGCACCCGTCAAAATTCGCGTTTGGGCGCAACACACAGATTTACCCGGCAAGGTGCGTGAAGTGGCT
GCGAGCAGCGATCCGGTGACGCGGACCTACCCTGTCAAGGTTTCTATTGATGCCAAGGAACCGCCCGTACTGGGCGCCAC
GGTGTCCGTGGTGCCTGAAGCGGGGGGCATTGCCGGTACGCCGGTCATCAAGCTGCCGACCACGGCCTTGCGCCAGGAAG
GCAATGCCACGGCGGTGTGGGTACTCGACAAGGCCAGCATGACCGTCAAGCCACAGGTGGTCCAGGTCGCCACGGCCGAT
GGCAACGACGTGGTGGTGGCGTCGGGCCTGCAGCCGGGCATGCTGGTCGTCAGCGCCGGCGTGCATGTGCTGTCGCCTGG
GCAGAAAGTGACCATTTACCAGCCCAGCGTGGCCATATCGACCGCCGCTCCTGCTCAATCAGCGCCTGATTCGATAGCGA
GTCCTGCAACGGCTGCTGCGGCTTCCAGCGCATCCGCGTCTGCCGCGAAGTGA

Upstream 100 bases:

>100_bases
GAGTGCTTGACAAGCCACTCCATTTATTTTAGATTACTAACCGGTCAGTCAGTAACTGATTGGCCCGATTTTTCACTCCC
GATTTTTACCGAACCAGACC

Downstream 100 bases:

>100_bases
GGCCGGCATGACGCAGGCAGACAACGGCACCGGCAGCCAGGCCGGCAACAACTCCAGCAACAACACCAGCAACGGCGCTC
TTCCTTCCCCCCGGTTCAAT

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKKTVFSLVSIAALLAACTPSAPPEEPVRAVKVMTVGTDAFSSSHEYAGEVRARVESRLGFRVGGKIIKRQAELGQRVKA
GQVLAQLDPQDYKLAVDAARAQVATAMTNRDLAAADFKRYKELKDQSFISGAELERRETTFKAAQAQLEQAQSQLAVQSN
QAGYAALVADVSGVVTAVEAEPGQVVAAGVPVVRIAADGVRDVVFSVPEDRVAGIKVGAPVKIRVWAQHTDLPGKVREVA
ASSDPVTRTYPVKVSIDAKEPPVLGATVSVVPEAGGIAGTPVIKLPTTALRQEGNATAVWVLDKASMTVKPQVVQVATAD
GNDVVVASGLQPGMLVVSAGVHVLSPGQKVTIYQPSVAISTAAPAQSAPDSIASPATAAAASSASASAAK

Sequences:

>Translated_390_residues
MKKTVFSLVSIAALLAACTPSAPPEEPVRAVKVMTVGTDAFSSSHEYAGEVRARVESRLGFRVGGKIIKRQAELGQRVKA
GQVLAQLDPQDYKLAVDAARAQVATAMTNRDLAAADFKRYKELKDQSFISGAELERRETTFKAAQAQLEQAQSQLAVQSN
QAGYAALVADVSGVVTAVEAEPGQVVAAGVPVVRIAADGVRDVVFSVPEDRVAGIKVGAPVKIRVWAQHTDLPGKVREVA
ASSDPVTRTYPVKVSIDAKEPPVLGATVSVVPEAGGIAGTPVIKLPTTALRQEGNATAVWVLDKASMTVKPQVVQVATAD
GNDVVVASGLQPGMLVVSAGVHVLSPGQKVTIYQPSVAISTAAPAQSAPDSIASPATAAAASSASASAAK
>Mature_390_residues
MKKTVFSLVSIAALLAACTPSAPPEEPVRAVKVMTVGTDAFSSSHEYAGEVRARVESRLGFRVGGKIIKRQAELGQRVKA
GQVLAQLDPQDYKLAVDAARAQVATAMTNRDLAAADFKRYKELKDQSFISGAELERRETTFKAAQAQLEQAQSQLAVQSN
QAGYAALVADVSGVVTAVEAEPGQVVAAGVPVVRIAADGVRDVVFSVPEDRVAGIKVGAPVKIRVWAQHTDLPGKVREVA
ASSDPVTRTYPVKVSIDAKEPPVLGATVSVVPEAGGIAGTPVIKLPTTALRQEGNATAVWVLDKASMTVKPQVVQVATAD
GNDVVVASGLQPGMLVVSAGVHVLSPGQKVTIYQPSVAISTAAPAQSAPDSIASPATAAAASSASASAAK

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=320, Percent_Identity=26.875, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081951, Length=191, Percent_Identity=28.2722513089005, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40195; Mature: 40195

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVFSLVSIAALLAACTPSAPPEEPVRAVKVMTVGTDAFSSSHEYAGEVRARVESRLG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHCCCCHHHHHHHHHHHHHHCC
FRVGGKIIKRQAELGQRVKAGQVLAQLDPQDYKLAVDAARAQVATAMTNRDLAAADFKRY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHH
KELKDQSFISGAELERRETTFKAAQAQLEQAQSQLAVQSNQAGYAALVADVSGVVTAVEA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCEEEEEEC
EPGQVVAAGVPVVRIAADGVRDVVFSVPEDRVAGIKVGAPVKIRVWAQHTDLPGKVREVA
CCCCEEEECCCEEEEECCCHHHHHHCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHH
ASSDPVTRTYPVKVSIDAKEPPVLGATVSVVPEAGGIAGTPVIKLPTTALRQEGNATAVW
CCCCCCCEEEEEEEEECCCCCCEECEEEEEEECCCCCCCCCEEECCHHHHHCCCCEEEEE
VLDKASMTVKPQVVQVATADGNDVVVASGLQPGMLVVSAGVHVLSPGQKVTIYQPSVAIS
EEECCCCEECCEEEEEEECCCCEEEEECCCCCCEEEEECCEEEECCCCEEEEECCCEEEE
TAAPAQSAPDSIASPATAAAASSASASAAK
ECCCCCCCCCHHCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKTVFSLVSIAALLAACTPSAPPEEPVRAVKVMTVGTDAFSSSHEYAGEVRARVESRLG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHCCCCHHHHHHHHHHHHHHCC
FRVGGKIIKRQAELGQRVKAGQVLAQLDPQDYKLAVDAARAQVATAMTNRDLAAADFKRY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHH
KELKDQSFISGAELERRETTFKAAQAQLEQAQSQLAVQSNQAGYAALVADVSGVVTAVEA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCEEEEEEC
EPGQVVAAGVPVVRIAADGVRDVVFSVPEDRVAGIKVGAPVKIRVWAQHTDLPGKVREVA
CCCCEEEECCCEEEEECCCHHHHHHCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHH
ASSDPVTRTYPVKVSIDAKEPPVLGATVSVVPEAGGIAGTPVIKLPTTALRQEGNATAVW
CCCCCCCEEEEEEEEECCCCCCEECEEEEEEECCCCCCCCCEEECCHHHHHCCCCEEEEE
VLDKASMTVKPQVVQVATADGNDVVVASGLQPGMLVVSAGVHVLSPGQKVTIYQPSVAIS
EEECCCCEECCEEEEEEECCCCEEEEECCCCCCEEEEECCEEEECCCCEEEEECCCEEEE
TAAPAQSAPDSIASPATAAAASSASASAAK
ECCCCCCCCCHHCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA