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The map label for this gene is cynR [H]

Identifier: 91787602

GI number: 91787602

Start: 1773389

End: 1774303

Strand: Reverse

Name: cynR [H]

Synonym: Bpro_1720

Alternate gene names: 91787602

Gene position: 1774303-1773389 (Counterclockwise)

Preceding gene: 91787607

Following gene: 91787601

Centisome position: 34.12

GC content: 67.65

Gene sequence:

>915_bases
ATGTCCTTGTCATTGCTGGGCACAGCCACCCGCTACTTTCTGGAGGTCGCCCGTACCGGCTCGGTGACCCAGGCGGCTGA
GCAGCTGCATGTGGCGGTATCGGCCGTCAGCCGCCAGATCACCAAACTCGAAGGCAGCCTGGGCTGTGCCTTGTTCGAGC
GCCAGGCCCGCGGCATGGCGCTCAGCGCTGCCGGGGAGCGGCTGGCCGCCTATGTGCGCACCACCATGCTCGATGCCGAA
CGCGTGGTCGACGAAGTCAAGGGGCTGGGCGGGCAACGCGCCAGCCGCATCCGCCTCGCCTGCACCGAAGGCCTGGCCTG
CGGCTTCATGGCGGAGGTGATGTCTTCATTTCGCACAGCGCATCCCGGCTGCGGCATTCACCTGCAGGTGGGCACGCCCG
ACGAAGTGAGCCGGCACCTGCTGCGCGGCGAGGTGGACCTGGGGATCAAATTTTCCGTCGCCCCGGAAAAGGGCCTGAAG
ATCGAACACAACCAGAGCGCCCCCATCATGGTGCTGGCGGCACCCGGCCATGCGCTGGCCCGGCGACGCAGTGTGTCGGT
GGCTGACATCGTGCGCCATCCGCTGGCCGTCCCCGAGGCCGGCACCACCGTGCGGCAGATGCTGGACCTGTGCTGCAGCC
TCAAGGGCCTGCACTACCAGGTGGCCTACACCGGCAATTACCCCACCTTGCTGGCGCTGGTCATGCAGGGCGAGGTGCTG
ACGCTCTCGGCGCTGGTCAGCGCCGCGCACGCCGTTCGGGCAGGTGAGTTGGTGGCCGTGCCGGTGAGCGAGCCGCAATT
TCGCCAGCGCAGCCTGCAAGTGCTGACACTGCAGGGGCAAACGCCCGGCACGCTGGCCAGCGACTTCAGGGATCACCTGA
TAGCGACTGCGCTCAGGCTTGGCCAGGCTGCTTAG

Upstream 100 bases:

>100_bases
CCAAAAGTCTAATAAACTCAAAAAGCTTTCACAATTTGAGAATAAGCAACTCAGCCTTGCGTTGGCGGCAATGCACGCAA
GCCACACGGGAAGCCATACG

Downstream 100 bases:

>100_bases
AGGATGTAAGAGCCAGGCACCCCAAACGACATCTGGGAAAATGCCTGTGCTGCAGGAACCCCTGAAATGAAACACCTTGT
TCTGTTAACCGCCTTGTTCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLSLLGTATRYFLEVARTGSVTQAAEQLHVAVSAVSRQITKLEGSLGCALFERQARGMALSAAGERLAAYVRTTMLDAE
RVVDEVKGLGGQRASRIRLACTEGLACGFMAEVMSSFRTAHPGCGIHLQVGTPDEVSRHLLRGEVDLGIKFSVAPEKGLK
IEHNQSAPIMVLAAPGHALARRRSVSVADIVRHPLAVPEAGTTVRQMLDLCCSLKGLHYQVAYTGNYPTLLALVMQGEVL
TLSALVSAAHAVRAGELVAVPVSEPQFRQRSLQVLTLQGQTPGTLASDFRDHLIATALRLGQAA

Sequences:

>Translated_304_residues
MSLSLLGTATRYFLEVARTGSVTQAAEQLHVAVSAVSRQITKLEGSLGCALFERQARGMALSAAGERLAAYVRTTMLDAE
RVVDEVKGLGGQRASRIRLACTEGLACGFMAEVMSSFRTAHPGCGIHLQVGTPDEVSRHLLRGEVDLGIKFSVAPEKGLK
IEHNQSAPIMVLAAPGHALARRRSVSVADIVRHPLAVPEAGTTVRQMLDLCCSLKGLHYQVAYTGNYPTLLALVMQGEVL
TLSALVSAAHAVRAGELVAVPVSEPQFRQRSLQVLTLQGQTPGTLASDFRDHLIATALRLGQAA
>Mature_303_residues
SLSLLGTATRYFLEVARTGSVTQAAEQLHVAVSAVSRQITKLEGSLGCALFERQARGMALSAAGERLAAYVRTTMLDAER
VVDEVKGLGGQRASRIRLACTEGLACGFMAEVMSSFRTAHPGCGIHLQVGTPDEVSRHLLRGEVDLGIKFSVAPEKGLKI
EHNQSAPIMVLAAPGHALARRRSVSVADIVRHPLAVPEAGTTVRQMLDLCCSLKGLHYQVAYTGNYPTLLALVMQGEVLT
LSALVSAAHAVRAGELVAVPVSEPQFRQRSLQVLTLQGQTPGTLASDFRDHLIATALRLGQAA

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=265, Percent_Identity=30.5660377358491, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787879, Length=307, Percent_Identity=27.0358306188925, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788481, Length=199, Percent_Identity=30.6532663316583, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=257, Percent_Identity=23.3463035019455, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693105, Length=266, Percent_Identity=22.9323308270677, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787530, Length=229, Percent_Identity=23.5807860262009, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=215, Percent_Identity=25.1162790697674, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=228, Percent_Identity=22.8070175438596, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790208, Length=139, Percent_Identity=29.4964028776978, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=304, Percent_Identity=24.6710526315789, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=202, Percent_Identity=26.7326732673267, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=219, Percent_Identity=26.9406392694064, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081904, Length=213, Percent_Identity=25.8215962441315, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=182, Percent_Identity=26.3736263736264, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=181, Percent_Identity=24.8618784530387, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789639, Length=165, Percent_Identity=24.8484848484848, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789204, Length=197, Percent_Identity=23.8578680203046, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32338; Mature: 32207

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSLLGTATRYFLEVARTGSVTQAAEQLHVAVSAVSRQITKLEGSLGCALFERQARGMA
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEE
LSAAGERLAAYVRTTMLDAERVVDEVKGLGGQRASRIRLACTEGLACGFMAEVMSSFRTA
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
HPGCGIHLQVGTPDEVSRHLLRGEVDLGIKFSVAPEKGLKIEHNQSAPIMVLAAPGHALA
CCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCEEEEECCCHHHH
RRRSVSVADIVRHPLAVPEAGTTVRQMLDLCCSLKGLHYQVAYTGNYPTLLALVMQGEVL
HHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCHH
TLSALVSAAHAVRAGELVAVPVSEPQFRQRSLQVLTLQGQTPGTLASDFRDHLIATALRL
HHHHHHHHHHHHCCCCEEEEECCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
GQAA
CCCC
>Mature Secondary Structure 
SLSLLGTATRYFLEVARTGSVTQAAEQLHVAVSAVSRQITKLEGSLGCALFERQARGMA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEE
LSAAGERLAAYVRTTMLDAERVVDEVKGLGGQRASRIRLACTEGLACGFMAEVMSSFRTA
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
HPGCGIHLQVGTPDEVSRHLLRGEVDLGIKFSVAPEKGLKIEHNQSAPIMVLAAPGHALA
CCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCEEEEECCCHHHH
RRRSVSVADIVRHPLAVPEAGTTVRQMLDLCCSLKGLHYQVAYTGNYPTLLALVMQGEVL
HHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCHH
TLSALVSAAHAVRAGELVAVPVSEPQFRQRSLQVLTLQGQTPGTLASDFRDHLIATALRL
HHHHHHHHHHHHCCCCEEEEECCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
GQAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]