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The map label for this gene is alsR [H]

Identifier: 91787554

GI number: 91787554

Start: 1726320

End: 1727207

Strand: Direct

Name: alsR [H]

Synonym: Bpro_1672

Alternate gene names: 91787554

Gene position: 1726320-1727207 (Clockwise)

Preceding gene: 91787545

Following gene: 91787555

Centisome position: 33.2

GC content: 67.57

Gene sequence:

>888_bases
ATGGAATTTCGCCACCTCCGCTATTTTCTGGTCCTGGCCGAAGAACTGCACTTCGGCCGGGCCGCGCGGCGCCTGTCGAT
TTCGCAGCCGCCGCTGTCGCTGAACATCCAGCAGCTGGAGGCCTCTGTCGGCGCGAAGCTGTTCACCCGCAACAGCAAGG
CGGTGCAATTGACGGCGGCGGGGCTGGCCTTTGTGCCGGCGGCGCGTGCGCTGATTGACCAGGCCGCGCAGGCGGCCAGC
CACGCGCGCGACGTGGGGCAGGGCATGGCCGGCAGCCTGGCCATCGGGTTTTCCGGCACCATGCTTTACAGCGGCTTGCC
CAACATCCTGGAGCGCTTCCAGGCCGAGCATCCTTTGCTGCGGCTGACGCTGAAGGAGCTCAGCTCCAGCGAGCAGCTGA
TCGAGCTGGCGCATGACCGGCTGGACCTCGGCTTTGTGCACACCACGCGCGTGCCGCCCGAGCTGTCGCAGATCCTCGTG
TCCAGCCAGGCGTTTGTGTGTTGCCTGCCGGCGGGCCATGCGCTGGCGCGCAAGCGCTCCTTGTCACTCAAGCAGTTGCA
CGGCGAGGCGTTTGCCGTGGTGTCGCGTGCGGTGTCGCCTGACTACCACGAGCGCATCCTGGCGATCTGCACCGAAGCCG
GCTTTTATCCGGAATTCCGCTACGAACTGCGGCACTGGCTGAGCGTGGTGTCGCTGGTGTCGCAAGGCATGGGCGTGGCG
CTGGTGCCGGCGGCGCTGCGGCAGTCGGCCATGGCCGGCGCGGCCTTTGTCCCGCTGGATGCCGTCACCACGCCTTACGA
CACGCACTGCCTCTGGAAGACTGCGCGCGACCACCAGTCGCTGGCGGCCTTTGTGAAAGCGGTGCGCGCCATCGCGCCGC
CCGTCTGA

Upstream 100 bases:

>100_bases
CTTCCGGCCCGTTGTAAGCGTTGTAAGTCACCCATTGTTTGACAAGCATGAATAGTTGTCTAATATCAAATAACGATTCA
ACGATACATTTTTTATATTC

Downstream 100 bases:

>100_bases
TCCCCTCTGAAAAGCCTGAAGGCTTTACATACAGGTGGCTCGCCCAAAGGCCCTTGCAAAAGTATGTCCCGCGCGCGAGA
CCTAAAGCTGTCACCATGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEFRHLRYFLVLAEELHFGRAARRLSISQPPLSLNIQQLEASVGAKLFTRNSKAVQLTAAGLAFVPAARALIDQAAQAAS
HARDVGQGMAGSLAIGFSGTMLYSGLPNILERFQAEHPLLRLTLKELSSSEQLIELAHDRLDLGFVHTTRVPPELSQILV
SSQAFVCCLPAGHALARKRSLSLKQLHGEAFAVVSRAVSPDYHERILAICTEAGFYPEFRYELRHWLSVVSLVSQGMGVA
LVPAALRQSAMAGAAFVPLDAVTTPYDTHCLWKTARDHQSLAAFVKAVRAIAPPV

Sequences:

>Translated_295_residues
MEFRHLRYFLVLAEELHFGRAARRLSISQPPLSLNIQQLEASVGAKLFTRNSKAVQLTAAGLAFVPAARALIDQAAQAAS
HARDVGQGMAGSLAIGFSGTMLYSGLPNILERFQAEHPLLRLTLKELSSSEQLIELAHDRLDLGFVHTTRVPPELSQILV
SSQAFVCCLPAGHALARKRSLSLKQLHGEAFAVVSRAVSPDYHERILAICTEAGFYPEFRYELRHWLSVVSLVSQGMGVA
LVPAALRQSAMAGAAFVPLDAVTTPYDTHCLWKTARDHQSLAAFVKAVRAIAPPV
>Mature_295_residues
MEFRHLRYFLVLAEELHFGRAARRLSISQPPLSLNIQQLEASVGAKLFTRNSKAVQLTAAGLAFVPAARALIDQAAQAAS
HARDVGQGMAGSLAIGFSGTMLYSGLPNILERFQAEHPLLRLTLKELSSSEQLIELAHDRLDLGFVHTTRVPPELSQILV
SSQAFVCCLPAGHALARKRSLSLKQLHGEAFAVVSRAVSPDYHERILAICTEAGFYPEFRYELRHWLSVVSLVSQGMGVA
LVPAALRQSAMAGAAFVPLDAVTTPYDTHCLWKTARDHQSLAAFVKAVRAIAPPV

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=267, Percent_Identity=34.8314606741573, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI2367136, Length=293, Percent_Identity=31.740614334471, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788887, Length=289, Percent_Identity=30.1038062283737, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI157672245, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790399, Length=247, Percent_Identity=27.1255060728745, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=25, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=37.2413793103448, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787601, Length=262, Percent_Identity=24.8091603053435, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=270, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789204, Length=247, Percent_Identity=29.1497975708502, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081904, Length=146, Percent_Identity=29.4520547945205, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994962, Length=156, Percent_Identity=30.1282051282051, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=22.3577235772358, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32095; Mature: 32095

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFRHLRYFLVLAEELHFGRAARRLSISQPPLSLNIQQLEASVGAKLFTRNSKAVQLTAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCEEEEEEC
GLAFVPAARALIDQAAQAASHARDVGQGMAGSLAIGFSGTMLYSGLPNILERFQAEHPLL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHCCHHHHHHHCCCCCHH
RLTLKELSSSEQLIELAHDRLDLGFVHTTRVPPELSQILVSSQAFVCCLPAGHALARKRS
HHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHC
LSLKQLHGEAFAVVSRAVSPDYHERILAICTEAGFYPEFRYELRHWLSVVSLVSQGMGVA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LVPAALRQSAMAGAAFVPLDAVTTPYDTHCLWKTARDHQSLAAFVKAVRAIAPPV
EHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFRHLRYFLVLAEELHFGRAARRLSISQPPLSLNIQQLEASVGAKLFTRNSKAVQLTAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCEEEEEEC
GLAFVPAARALIDQAAQAASHARDVGQGMAGSLAIGFSGTMLYSGLPNILERFQAEHPLL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHCCHHHHHHHCCCCCHH
RLTLKELSSSEQLIELAHDRLDLGFVHTTRVPPELSQILVSSQAFVCCLPAGHALARKRS
HHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHC
LSLKQLHGEAFAVVSRAVSPDYHERILAICTEAGFYPEFRYELRHWLSVVSLVSQGMGVA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LVPAALRQSAMAGAAFVPLDAVTTPYDTHCLWKTARDHQSLAAFVKAVRAIAPPV
EHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]