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The map label for this gene is mmgC [H]

Identifier: 91787553

GI number: 91787553

Start: 1724923

End: 1726119

Strand: Reverse

Name: mmgC [H]

Synonym: Bpro_1671

Alternate gene names: 91787553

Gene position: 1726119-1724923 (Counterclockwise)

Preceding gene: 91787557

Following gene: 91787552

Centisome position: 33.19

GC content: 62.24

Gene sequence:

>1197_bases
ATGAAAACCAAATTCAGCTGGGAAGACCCCCTGTTCCTGATGGAGCAGCTCAGCGACGACGAGCGCGCCATCGTGCACGC
CGCGCACGAGTTCTGCCAGGAAAAACTGCAGCCCCGCGTGCTGATGGCCGCACGCCACGAAAAGTTCGACCGCGAGATCA
TGAATGAAGCGGGCGCCATGGGCTTTCTGGGTTCGACCATTGAAGGCTACGGCTGCGCCGGCCTCAATTACGTCAGTTAC
GGCCTGGTGGCGCGCGAAGTGGAGCGCGTGGACAGCGGCTACCGCAGCGCCATCAGCGTGCAAAGCTCGCTGGTCATGCA
CCCGATCCATGCCTATGGCAGCGAGGCGCAGCGCCAGAAGTATTTGCCCAAGCTCGCCACCGGCGAATGGGTCGGCTGCT
TCGGCCTGACCGAGCCCAACCACGGCTCCGACCCGGCCAGCATGCTGACGCGGGCCAAGCCCGTTGACGGGGGTTTCATC
CTCAAGGGCTCCAAGATGTGGATCACCAACAGCCCGATTGCGGACGTGTTTGTGGTCTGGGCCAAGCTGGAAGACCCCGA
CGGCAAGGTCGGCGGCCAGGAAAGCATCCGCGGCTTCCTGCTGGAAAAAGGCATGAAGGGCCTTTCCGCCCCCAAGATCG
AGGGCAAGATGAGCTTGCGCGCCTCCATCACCGGTGAAATTGTCATGGACGACGTGTTTGTGCCCGAAGCGAATTTGCTG
CCCAATGTGAGCGGCCTGAAAGGCCCGTTCGGATGCCTGAACAAGGCGCGCTACGGTATTGCCTGGGGCGCCCTGGGGGC
TGCCGAAGACTGCTGGTTCCGCGCCCGCCAGTACACCATGGACCGCCAGCAGTTCGGCCGCCCGCTGGCGCAAAACCAGC
TCATTCAAAAGAAGCTCGCAGACATGCAAACCGAGATCACGCTGGGCCTGCAAGCCTGCCTGCGCGTGGGCCGCCTGATG
GACGAGGACAAGGCCATGCCTGAAATGATTTCGCTGATCAAGCGCAACTCCTGCGGCAAGTCGCTCGACATCGCCCGCAT
GGCGCGCGACATGCACGGCGGCAACGGCATCCATGACGAATACCACGTGATCCGCCACATGATCAACCTGGAGACCGTCA
ACACCTACGAAGGCACGCACGATGTGCACGCGCTGATTTTGGGGCGTGCGCAAACCGGCCTGCAGGCTTTTTACTGA

Upstream 100 bases:

>100_bases
GCGGCGCAATGCGGCGCCCCAAGCCCTACACTTTGCAAAAGCCCCAACGCACTTCAGCGCACCTCAACGCATCTCGAATG
CATCCAGAAGGAGACTCACC

Downstream 100 bases:

>100_bases
TACTGAGCTTTCAGGTGCGGCCGCCCCGGCGCGCGGGGTACTATCAGTTTCTTTTTTTATAGCAATTGATGGAATTCGGC
ACCCTCAGACCGCTGCTGGC

Product: acyl-CoA dehydrogenase-like protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKTKFSWEDPLFLMEQLSDDERAIVHAAHEFCQEKLQPRVLMAARHEKFDREIMNEAGAMGFLGSTIEGYGCAGLNYVSY
GLVAREVERVDSGYRSAISVQSSLVMHPIHAYGSEAQRQKYLPKLATGEWVGCFGLTEPNHGSDPASMLTRAKPVDGGFI
LKGSKMWITNSPIADVFVVWAKLEDPDGKVGGQESIRGFLLEKGMKGLSAPKIEGKMSLRASITGEIVMDDVFVPEANLL
PNVSGLKGPFGCLNKARYGIAWGALGAAEDCWFRARQYTMDRQQFGRPLAQNQLIQKKLADMQTEITLGLQACLRVGRLM
DEDKAMPEMISLIKRNSCGKSLDIARMARDMHGGNGIHDEYHVIRHMINLETVNTYEGTHDVHALILGRAQTGLQAFY

Sequences:

>Translated_398_residues
MKTKFSWEDPLFLMEQLSDDERAIVHAAHEFCQEKLQPRVLMAARHEKFDREIMNEAGAMGFLGSTIEGYGCAGLNYVSY
GLVAREVERVDSGYRSAISVQSSLVMHPIHAYGSEAQRQKYLPKLATGEWVGCFGLTEPNHGSDPASMLTRAKPVDGGFI
LKGSKMWITNSPIADVFVVWAKLEDPDGKVGGQESIRGFLLEKGMKGLSAPKIEGKMSLRASITGEIVMDDVFVPEANLL
PNVSGLKGPFGCLNKARYGIAWGALGAAEDCWFRARQYTMDRQQFGRPLAQNQLIQKKLADMQTEITLGLQACLRVGRLM
DEDKAMPEMISLIKRNSCGKSLDIARMARDMHGGNGIHDEYHVIRHMINLETVNTYEGTHDVHALILGRAQTGLQAFY
>Mature_398_residues
MKTKFSWEDPLFLMEQLSDDERAIVHAAHEFCQEKLQPRVLMAARHEKFDREIMNEAGAMGFLGSTIEGYGCAGLNYVSY
GLVAREVERVDSGYRSAISVQSSLVMHPIHAYGSEAQRQKYLPKLATGEWVGCFGLTEPNHGSDPASMLTRAKPVDGGFI
LKGSKMWITNSPIADVFVVWAKLEDPDGKVGGQESIRGFLLEKGMKGLSAPKIEGKMSLRASITGEIVMDDVFVPEANLL
PNVSGLKGPFGCLNKARYGIAWGALGAAEDCWFRARQYTMDRQQFGRPLAQNQLIQKKLADMQTEITLGLQACLRVGRLM
DEDKAMPEMISLIKRNSCGKSLDIARMARDMHGGNGIHDEYHVIRHMINLETVNTYEGTHDVHALILGRAQTGLQAFY

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=398, Percent_Identity=68.8442211055276, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI7669494, Length=378, Percent_Identity=67.989417989418, Blast_Score=532, Evalue=1e-151,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=32.2751322751323, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=32.3699421965318, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI4501859, Length=372, Percent_Identity=30.3763440860215, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=28.9893617021277, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI4557235, Length=345, Percent_Identity=34.4927536231884, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=32.8205128205128, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=29.287598944591, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=29.287598944591, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=29.7082228116711, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI21361497, Length=399, Percent_Identity=28.8220551378446, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=29.4906166219839, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI48976061, Length=279, Percent_Identity=24.7311827956989, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI211971008, Length=279, Percent_Identity=24.7311827956989, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786223, Length=279, Percent_Identity=25.4480286738351, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081958, Length=329, Percent_Identity=25.8358662613982, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87081702, Length=270, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534353, Length=393, Percent_Identity=65.9033078880407, Blast_Score=544, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17538396, Length=393, Percent_Identity=31.2977099236641, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=29.8387096774194, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17534899, Length=377, Percent_Identity=30.5039787798408, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=376, Percent_Identity=28.9893617021277, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=28.6472148541114, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=30.7042253521127, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=27.3712737127371, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=264, Percent_Identity=33.7121212121212, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=263, Percent_Identity=32.6996197718631, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=378, Percent_Identity=26.1904761904762, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=28.8256227758007, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=34.4978165938865, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=405, Percent_Identity=23.4567901234568, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=23.7467018469657, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920834, Length=398, Percent_Identity=67.0854271356784, Blast_Score=534, Evalue=1e-152,
Organism=Drosophila melanogaster, GI24666513, Length=369, Percent_Identity=30.6233062330623, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=29.1777188328912, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=30.3430079155673, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=29.7872340425532, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=29.7650130548303, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=31.6568047337278, Blast_Score=145, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 44129; Mature: 44129

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKFSWEDPLFLMEQLSDDERAIVHAAHEFCQEKLQPRVLMAARHEKFDREIMNEAGAM
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
GFLGSTIEGYGCAGLNYVSYGLVAREVERVDSGYRSAISVQSSLVMHPIHAYGSEAQRQK
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YLPKLATGEWVGCFGLTEPNHGSDPASMLTRAKPVDGGFILKGSKMWITNSPIADVFVVW
CCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEECCEEEEECCCHHHHEEEE
AKLEDPDGKVGGQESIRGFLLEKGMKGLSAPKIEGKMSLRASITGEIVMDDVFVPEANLL
EEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEECEECCCCCCC
PNVSGLKGPFGCLNKARYGIAWGALGAAEDCWFRARQYTMDRQQFGRPLAQNQLIQKKLA
CCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
DMQTEITLGLQACLRVGRLMDEDKAMPEMISLIKRNSCGKSLDIARMARDMHGGNGIHDE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHH
YHVIRHMINLETVNTYEGTHDVHALILGRAQTGLQAFY
HHHHHHHHHHCEEECCCCCHHHHHHEEHHHHHHHHHCC
>Mature Secondary Structure
MKTKFSWEDPLFLMEQLSDDERAIVHAAHEFCQEKLQPRVLMAARHEKFDREIMNEAGAM
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
GFLGSTIEGYGCAGLNYVSYGLVAREVERVDSGYRSAISVQSSLVMHPIHAYGSEAQRQK
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YLPKLATGEWVGCFGLTEPNHGSDPASMLTRAKPVDGGFILKGSKMWITNSPIADVFVVW
CCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEECCEEEEECCCHHHHEEEE
AKLEDPDGKVGGQESIRGFLLEKGMKGLSAPKIEGKMSLRASITGEIVMDDVFVPEANLL
EEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEECEECCCCCCC
PNVSGLKGPFGCLNKARYGIAWGALGAAEDCWFRARQYTMDRQQFGRPLAQNQLIQKKLA
CCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
DMQTEITLGLQACLRVGRLMDEDKAMPEMISLIKRNSCGKSLDIARMARDMHGGNGIHDE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHH
YHVIRHMINLETVNTYEGTHDVHALILGRAQTGLQAFY
HHHHHHHHHHCEEECCCCCHHHHHHEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]