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The map label for this gene is pip [H]

Identifier: 91787487

GI number: 91787487

Start: 1654162

End: 1655151

Strand: Direct

Name: pip [H]

Synonym: Bpro_1603

Alternate gene names: 91787487

Gene position: 1654162-1655151 (Clockwise)

Preceding gene: 91787482

Following gene: 91787488

Centisome position: 31.81

GC content: 68.18

Gene sequence:

>990_bases
ATGACCTCCTCGGCCTCTGACCTCCCGACCCGCCCTTCCGGCCGCTCCAGGCCGTTTCTCTACCCGCCCATCGAGCCTTT
CCGCACCGGCGTGCTGGAGACGGGTGACGGCCATTCGATTTACTGGGAGCTGTGCGGCAACCCGGCAGGCAAGCCCGCGG
TTTTCCTGCACGGCGGGCCTGGCTCCGGCTGCTCCCCCGACCACCGGCGGCTGTTTGACCCCAAGCGCTACTGTGTTTTG
CTGTTCGACCAGCGCGGCTGCGGCCGCTCGCGCCCCAGTGCCTCGCTGGACAACAACACCACCTGGCACCTGGTGGCCGA
CATCGAGCGGCTGCGCACCCTGCTGGGCGTGGAACGCTGGGTGGTATTTGGCGGTTCCTGGGGCAGCTCACTGGCGCTGG
CCTATGCCCAGACGCACCCCGCCCAGGTGTCGGCCCTCATCGTGCGCGGCATTTTTACGCTGCGGCGCGCCGAACTGCTC
TGGTACTACCAGGAGGGGGCCTCCTGGCTGTTTCCGGACCTGTGGGAGGCGTTTCTGGCGCCCATCCCGCCGGCTGAGCG
AGGCGATCTGATGGCCGCCTACCGCAAGCGGCTGGTGGGGTCCAACCGGGCCGAGCAGCTGGCCTGCGCCCGGGCCTGGA
GCCTGTGGGAGGGCCAGACCATCACGCTGCTGCCCGATGAGGCCGCCACCGCCAAACATGCAGCGGATGACTTCGCGCTG
GCATTCGCCCGCATCGAAAACCATTACTTCGTGCATGCCGGCTGGCTGGAGGAGGGCCAGCTGATCCGTGACGCCGGCAA
GCTGGCTGGCATTCCCGGCGTCATCGTGCAGGGACGCTACGACATGGCCACGCCCGCCAAAACCGCCTGGGACCTGCACC
GCGCCTGGCCGGAGGCGGACTTTCACCTGATCGACGATGCCGGGCACGCCTTCAATGAGCCTGGCATCCTGCAGCAGCTG
ATGGCCGCGACCGACCGTTTCGCAGCATGA

Upstream 100 bases:

>100_bases
GTTGATGGTGGGCCAACACTGGAATAATGCCAGCACGCCCCTGCAGTAGCCCGTAGCTGTTGCGGCCTTTTCCCTGCCCC
CATTTTGATGGACGACGCCC

Downstream 100 bases:

>100_bases
ACGAGCGCTGGATGAGGCGTCTCGCGTTAGCAGGGGCCGCCGGTCCGGCTTTGCCGGCCGCAGGCGCCGCCCCCTGCAAG
GGGGGAGGACCCTACACGCA

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTSSASDLPTRPSGRSRPFLYPPIEPFRTGVLETGDGHSIYWELCGNPAGKPAVFLHGGPGSGCSPDHRRLFDPKRYCVL
LFDQRGCGRSRPSASLDNNTTWHLVADIERLRTLLGVERWVVFGGSWGSSLALAYAQTHPAQVSALIVRGIFTLRRAELL
WYYQEGASWLFPDLWEAFLAPIPPAERGDLMAAYRKRLVGSNRAEQLACARAWSLWEGQTITLLPDEAATAKHAADDFAL
AFARIENHYFVHAGWLEEGQLIRDAGKLAGIPGVIVQGRYDMATPAKTAWDLHRAWPEADFHLIDDAGHAFNEPGILQQL
MAATDRFAA

Sequences:

>Translated_329_residues
MTSSASDLPTRPSGRSRPFLYPPIEPFRTGVLETGDGHSIYWELCGNPAGKPAVFLHGGPGSGCSPDHRRLFDPKRYCVL
LFDQRGCGRSRPSASLDNNTTWHLVADIERLRTLLGVERWVVFGGSWGSSLALAYAQTHPAQVSALIVRGIFTLRRAELL
WYYQEGASWLFPDLWEAFLAPIPPAERGDLMAAYRKRLVGSNRAEQLACARAWSLWEGQTITLLPDEAATAKHAADDFAL
AFARIENHYFVHAGWLEEGQLIRDAGKLAGIPGVIVQGRYDMATPAKTAWDLHRAWPEADFHLIDDAGHAFNEPGILQQL
MAATDRFAA
>Mature_328_residues
TSSASDLPTRPSGRSRPFLYPPIEPFRTGVLETGDGHSIYWELCGNPAGKPAVFLHGGPGSGCSPDHRRLFDPKRYCVLL
FDQRGCGRSRPSASLDNNTTWHLVADIERLRTLLGVERWVVFGGSWGSSLALAYAQTHPAQVSALIVRGIFTLRRAELLW
YYQEGASWLFPDLWEAFLAPIPPAERGDLMAAYRKRLVGSNRAEQLACARAWSLWEGQTITLLPDEAATAKHAADDFALA
FARIENHYFVHAGWLEEGQLIRDAGKLAGIPGVIVQGRYDMATPAKTAWDLHRAWPEADFHLIDDAGHAFNEPGILQQLM
AATDRFAA

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36421; Mature: 36289

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSASDLPTRPSGRSRPFLYPPIEPFRTGVLETGDGHSIYWELCGNPAGKPAVFLHGGP
CCCCCCCCCCCCCCCCCCEECCCCCHHHCCCEECCCCCEEEEEECCCCCCCCEEEEECCC
GSGCSPDHRRLFDPKRYCVLLFDQRGCGRSRPSASLDNNTTWHLVADIERLRTLLGVERW
CCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEE
VVFGGSWGSSLALAYAQTHPAQVSALIVRGIFTLRRAELLWYYQEGASWLFPDLWEAFLA
EEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHC
PIPPAERGDLMAAYRKRLVGSNRAEQLACARAWSLWEGQTITLLPDEAATAKHAADDFAL
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
AFARIENHYFVHAGWLEEGQLIRDAGKLAGIPGVIVQGRYDMATPAKTAWDLHRAWPEAD
HHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCC
FHLIDDAGHAFNEPGILQQLMAATDRFAA
EEEEECCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSSASDLPTRPSGRSRPFLYPPIEPFRTGVLETGDGHSIYWELCGNPAGKPAVFLHGGP
CCCCCCCCCCCCCCCCCEECCCCCHHHCCCEECCCCCEEEEEECCCCCCCCEEEEECCC
GSGCSPDHRRLFDPKRYCVLLFDQRGCGRSRPSASLDNNTTWHLVADIERLRTLLGVERW
CCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEE
VVFGGSWGSSLALAYAQTHPAQVSALIVRGIFTLRRAELLWYYQEGASWLFPDLWEAFLA
EEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHC
PIPPAERGDLMAAYRKRLVGSNRAEQLACARAWSLWEGQTITLLPDEAATAKHAADDFAL
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
AFARIENHYFVHAGWLEEGQLIRDAGKLAGIPGVIVQGRYDMATPAKTAWDLHRAWPEAD
HHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCC
FHLIDDAGHAFNEPGILQQLMAATDRFAA
EEEEECCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]