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The map label for this gene is maeB [H]

Identifier: 91787316

GI number: 91787316

Start: 1465921

End: 1468224

Strand: Reverse

Name: maeB [H]

Synonym: Bpro_1421

Alternate gene names: 91787316

Gene position: 1468224-1465921 (Counterclockwise)

Preceding gene: 91787317

Following gene: 91787315

Centisome position: 28.23

GC content: 65.67

Gene sequence:

>2304_bases
ATGGCTACTCCTCTTTCACCCGCTGAAGAAGCACTGCGCGACGCCGCCCGTGAATACCACCGCAGCCCGGTGCGCGGCAA
GATATCCATCACGCCGACCAAACCGCTGTCGAACCAGCGGGACCTGTCCCTGGCGTATTCGCCCGGCGTGGCCTACCCCT
GCCTTGACATCGAGGCCGACCCCTCGCTGGCGGCCGAATACACCTCGCGCGGCAACCTCGTGGGGGTCATCACCAATGGC
ACGGCCGTCCTGGGACTGGGCGACATCGGCCCGCTGGCAGCCAAGCCGGTGATGGAAGGCAAGGGTTGCCTGTTCAAGAA
ATTCGCCGGTATCGACGTGTTTGACATCGAACTGGCCGAGCACGACCCCGACAAGCTGATTGACATCATCGCCGCCATGG
AGCCCACGCTGGGCGGCATCAACCTCGAGGACATCAAGGCGCCGGAGTGCTTTTACATCGAGCGCAAGCTGCGCGAGCGC
ATGAACATCCCGGTGTTCCATGACGACCAGCACGGCACCGCCATCATCTCATCGGCGGCCGTGCTCAACGGCCTGGAGCT
GGTGGGCAAGCGGATTGAAGACGTCAGGATCGCGGTCTCGGGGGCCGGAGCGGCCGCACTGGCCTGCCTGGACGTGATGG
TGGGCCTGGGGGTGCGCCGTGAAAATGTCTATGTCTGCGACTCCAAAGGCGTGATCTACCACGGCCGCCCCGGTGGTTTT
GACGAGTCCAAGAACCGCTTTGCCCAGGAAACGGCCCTGCGCACACTGGCCGACGCGGTCAACGGTGCGGACGTGTTTCT
GGGGTGCTCGGCGCCCGGCGTGCTGACGCAGGACATGGTCAGGACCATGGCCCCCAGCCCGATCATTCTGGCGCTGGCCA
ACCCCGAACCGGAAATCCGGCCCGAGCTGGCCAAGGCGGTGCGGCCGGACTGCATCATTGCCACGGGCCGTTCGGACTAC
CCGAACCAGGTCAACAATGTCCTGTGTTTCCCCTACATCTTTCGCGGCGCGCTCGATTGCGGCGCCACCAAGATCACCGA
GGAAATGAAGCTCGCCTGCGTGCGGCAGATTGCCGACCTGACCAAGGCGGACATCAGCGAGGAAGTCGCCCGGGCCTATA
TCGGGCAGGAGCTGGTGTTTGGCCCCGACTACATCATTCCCAAGCCTTTTGACTCGCGCCTGATTCTCAGGATCGCACCG
GCGGTGGCGCAGGCCGCCGAGGACTCCGGCGTGGCGACCCGGCCCATCACGGACATGGCCGCTTACCGGCAGGAACTGTC
GCGTTTCGTGTACTCGACCGGCATGCTCATGCAACCGGTGTTCAATGCGGCTCGCGCCATCCCGGACGCGCACAAACGCG
TGGCCTTCGCCGAAGGGGAGGACGACCGGGTGCTGCGCGCGGCGCAGCTGGTGCTTGACGAAGGCCTGGCCCGCCCCATC
CTCATCGGCCGCCCTGCCGTGATCGAGACCCGCATCGCCAAGGCCGGACTGCGGCTGCGGCTCGGCGACGATGTGGAATG
CGTCAATCCCGAGGACGACCCGCGCTTTCGCCATTACTGGGAAACCTACCACCGGATCATGGGCCGCCACGGCGTGACGC
CCGAAGCCGCCAAGGCGGCGGTGCGCCGCTCCACCACCACCATCGCCGCGCTGATGGTCAAACTCGGCGACGCCGATGCC
ATGCTGTGCGGCATGGTGGGCCGCTACGACGGACATCTTGAGCATGTACGCGACATCATCGGGCTCAAAGAGGATGCGTC
CGGGTTTGCGGCGCTCAACGCACTGATGCTGGACAAACGCACCCTGTTCATCGCCGACACCTTTGTCAACGAAGACCCCA
GCGCCGAGCAGCTGGCCAGCATTGCGCTGATGGCGGTCGACGAGGTGCGGCGCTTCGGCATCCCGCCCAAGGTGGCCTTT
CTGTCGCACTCCAACTACGGCTCGTCCAACCGTGCGTCGGCGCGCAAGATGCGGCTGGCCCACGAGCTGTTCGCCAGGAT
GGCGCCCGACGTGGAGTCCGATGGCGAGCTGCATGGCGATGCGGCGCTGTCGGAAGAGGTGCGGCGGGCGTCCCTGATGG
AAAGCAATATGAGCGGGGAAGCCAACATCCTGATTTGCCCGAATCTGGATTCCGCCAACATCCTCTTCAACGTGCTCAAG
ATGACGGGCGGCCAGGGCGTCACCGTCGGCCCCATTCTGCTCGGCACGGCCGCCTCGGCCCACATCCTGACCACCTCGGC
CACCGTGCGGCGCGTGGTGAACATGACGGCACTGGCCGTGGCCAGCGCGGCAGCGCGGCGCTGA

Upstream 100 bases:

>100_bases
CGTGCGCATGAACCGGAAAGCCGGCGCTCGACCGCATGAATACCAGAAAATAGTGCTGGTCGCCAGTCTTCCAGCCATCA
GGAAAACAAGGAGACACTCA

Downstream 100 bases:

>100_bases
CACGCGCCCCGGCACCAGTCCTGGAGCAGTGACATGCACCATCCGGAGCCTTCCCCCTCAAAACTCCCGCTGCGGCGGGA
GTTTTGCTTTCCGGAGGCGC

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MATPLSPAEEALRDAAREYHRSPVRGKISITPTKPLSNQRDLSLAYSPGVAYPCLDIEADPSLAAEYTSRGNLVGVITNG
TAVLGLGDIGPLAAKPVMEGKGCLFKKFAGIDVFDIELAEHDPDKLIDIIAAMEPTLGGINLEDIKAPECFYIERKLRER
MNIPVFHDDQHGTAIISSAAVLNGLELVGKRIEDVRIAVSGAGAAALACLDVMVGLGVRRENVYVCDSKGVIYHGRPGGF
DESKNRFAQETALRTLADAVNGADVFLGCSAPGVLTQDMVRTMAPSPIILALANPEPEIRPELAKAVRPDCIIATGRSDY
PNQVNNVLCFPYIFRGALDCGATKITEEMKLACVRQIADLTKADISEEVARAYIGQELVFGPDYIIPKPFDSRLILRIAP
AVAQAAEDSGVATRPITDMAAYRQELSRFVYSTGMLMQPVFNAARAIPDAHKRVAFAEGEDDRVLRAAQLVLDEGLARPI
LIGRPAVIETRIAKAGLRLRLGDDVECVNPEDDPRFRHYWETYHRIMGRHGVTPEAAKAAVRRSTTTIAALMVKLGDADA
MLCGMVGRYDGHLEHVRDIIGLKEDASGFAALNALMLDKRTLFIADTFVNEDPSAEQLASIALMAVDEVRRFGIPPKVAF
LSHSNYGSSNRASARKMRLAHELFARMAPDVESDGELHGDAALSEEVRRASLMESNMSGEANILICPNLDSANILFNVLK
MTGGQGVTVGPILLGTAASAHILTTSATVRRVVNMTALAVASAAARR

Sequences:

>Translated_767_residues
MATPLSPAEEALRDAAREYHRSPVRGKISITPTKPLSNQRDLSLAYSPGVAYPCLDIEADPSLAAEYTSRGNLVGVITNG
TAVLGLGDIGPLAAKPVMEGKGCLFKKFAGIDVFDIELAEHDPDKLIDIIAAMEPTLGGINLEDIKAPECFYIERKLRER
MNIPVFHDDQHGTAIISSAAVLNGLELVGKRIEDVRIAVSGAGAAALACLDVMVGLGVRRENVYVCDSKGVIYHGRPGGF
DESKNRFAQETALRTLADAVNGADVFLGCSAPGVLTQDMVRTMAPSPIILALANPEPEIRPELAKAVRPDCIIATGRSDY
PNQVNNVLCFPYIFRGALDCGATKITEEMKLACVRQIADLTKADISEEVARAYIGQELVFGPDYIIPKPFDSRLILRIAP
AVAQAAEDSGVATRPITDMAAYRQELSRFVYSTGMLMQPVFNAARAIPDAHKRVAFAEGEDDRVLRAAQLVLDEGLARPI
LIGRPAVIETRIAKAGLRLRLGDDVECVNPEDDPRFRHYWETYHRIMGRHGVTPEAAKAAVRRSTTTIAALMVKLGDADA
MLCGMVGRYDGHLEHVRDIIGLKEDASGFAALNALMLDKRTLFIADTFVNEDPSAEQLASIALMAVDEVRRFGIPPKVAF
LSHSNYGSSNRASARKMRLAHELFARMAPDVESDGELHGDAALSEEVRRASLMESNMSGEANILICPNLDSANILFNVLK
MTGGQGVTVGPILLGTAASAHILTTSATVRRVVNMTALAVASAAARR
>Mature_766_residues
ATPLSPAEEALRDAAREYHRSPVRGKISITPTKPLSNQRDLSLAYSPGVAYPCLDIEADPSLAAEYTSRGNLVGVITNGT
AVLGLGDIGPLAAKPVMEGKGCLFKKFAGIDVFDIELAEHDPDKLIDIIAAMEPTLGGINLEDIKAPECFYIERKLRERM
NIPVFHDDQHGTAIISSAAVLNGLELVGKRIEDVRIAVSGAGAAALACLDVMVGLGVRRENVYVCDSKGVIYHGRPGGFD
ESKNRFAQETALRTLADAVNGADVFLGCSAPGVLTQDMVRTMAPSPIILALANPEPEIRPELAKAVRPDCIIATGRSDYP
NQVNNVLCFPYIFRGALDCGATKITEEMKLACVRQIADLTKADISEEVARAYIGQELVFGPDYIIPKPFDSRLILRIAPA
VAQAAEDSGVATRPITDMAAYRQELSRFVYSTGMLMQPVFNAARAIPDAHKRVAFAEGEDDRVLRAAQLVLDEGLARPIL
IGRPAVIETRIAKAGLRLRLGDDVECVNPEDDPRFRHYWETYHRIMGRHGVTPEAAKAAVRRSTTTIAALMVKLGDADAM
LCGMVGRYDGHLEHVRDIIGLKEDASGFAALNALMLDKRTLFIADTFVNEDPSAEQLASIALMAVDEVRRFGIPPKVAFL
SHSNYGSSNRASARKMRLAHELFARMAPDVESDGELHGDAALSEEVRRASLMESNMSGEANILICPNLDSANILFNVLKM
TGGQGVTVGPILLGTAASAHILTTSATVRRVVNMTALAVASAAARR

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=357, Percent_Identity=26.890756302521, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI4505145, Length=358, Percent_Identity=28.2122905027933, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI62420882, Length=368, Percent_Identity=25.2717391304348, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI62420880, Length=368, Percent_Identity=25.2717391304348, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI239049447, Length=368, Percent_Identity=25.2717391304348, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI270265879, Length=317, Percent_Identity=29.3375394321767, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI1788806, Length=759, Percent_Identity=61.133069828722, Blast_Score=949, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=316, Percent_Identity=31.6455696202532, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1788635, Length=318, Percent_Identity=27.6729559748428, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI87081919, Length=294, Percent_Identity=23.1292517006803, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322823, Length=270, Percent_Identity=29.2592592592593, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24646388, Length=349, Percent_Identity=30.945558739255, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646386, Length=349, Percent_Identity=30.945558739255, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281362672, Length=478, Percent_Identity=26.5690376569038, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362674, Length=478, Percent_Identity=26.5690376569038, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356279, Length=478, Percent_Identity=26.5690376569038, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78707242, Length=341, Percent_Identity=25.5131964809384, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI78707238, Length=341, Percent_Identity=25.5131964809384, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI78707240, Length=341, Percent_Identity=25.5131964809384, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 82668; Mature: 82537

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPLSPAEEALRDAAREYHRSPVRGKISITPTKPLSNQRDLSLAYSPGVAYPCLDIEAD
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEEECCCC
PSLAAEYTSRGNLVGVITNGTAVLGLGDIGPLAAKPVMEGKGCLFKKFAGIDVFDIELAE
CCHHHHHCCCCCEEEEEECCEEEEEECCCCCHHCCCCCCCCCCHHHHHCCCEEEEEEECC
HDPDKLIDIIAAMEPTLGGINLEDIKAPECFYIERKLRERMNIPVFHDDQHGTAIISSAA
CCHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHH
VLNGLELVGKRIEDVRIAVSGAGAAALACLDVMVGLGVRRENVYVCDSKGVIYHGRPGGF
HHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHCCCEECCEEEECCCCEEEECCCCCC
DESKNRFAQETALRTLADAVNGADVFLGCSAPGVLTQDMVRTMAPSPIILALANPEPEIR
CHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PELAKAVRPDCIIATGRSDYPNQVNNVLCFPYIFRGALDCGATKITEEMKLACVRQIADL
HHHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TKADISEEVARAYIGQELVFGPDYIIPKPFDSRLILRIAPAVAQAAEDSGVATRPITDMA
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHH
AYRQELSRFVYSTGMLMQPVFNAARAIPDAHKRVAFAEGEDDRVLRAAQLVLDEGLARPI
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCEEECCCCCHHHHHHHHHHHHCCCCCCE
LIGRPAVIETRIAKAGLRLRLGDDVECVNPEDDPRFRHYWETYHRIMGRHGVTPEAAKAA
EECCCHHHHHHHHHCCCEEEECCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
VRRSTTTIAALMVKLGDADAMLCGMVGRYDGHLEHVRDIIGLKEDASGFAALNALMLDKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
TLFIADTFVNEDPSAEQLASIALMAVDEVRRFGIPPKVAFLSHSNYGSSNRASARKMRLA
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHH
HELFARMAPDVESDGELHGDAALSEEVRRASLMESNMSGEANILICPNLDSANILFNVLK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
MTGGQGVTVGPILLGTAASAHILTTSATVRRVVNMTALAVASAAARR
HCCCCCCEECHHHEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPLSPAEEALRDAAREYHRSPVRGKISITPTKPLSNQRDLSLAYSPGVAYPCLDIEAD
CCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEEECCCC
PSLAAEYTSRGNLVGVITNGTAVLGLGDIGPLAAKPVMEGKGCLFKKFAGIDVFDIELAE
CCHHHHHCCCCCEEEEEECCEEEEEECCCCCHHCCCCCCCCCCHHHHHCCCEEEEEEECC
HDPDKLIDIIAAMEPTLGGINLEDIKAPECFYIERKLRERMNIPVFHDDQHGTAIISSAA
CCHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHH
VLNGLELVGKRIEDVRIAVSGAGAAALACLDVMVGLGVRRENVYVCDSKGVIYHGRPGGF
HHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHCCCEECCEEEECCCCEEEECCCCCC
DESKNRFAQETALRTLADAVNGADVFLGCSAPGVLTQDMVRTMAPSPIILALANPEPEIR
CHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PELAKAVRPDCIIATGRSDYPNQVNNVLCFPYIFRGALDCGATKITEEMKLACVRQIADL
HHHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TKADISEEVARAYIGQELVFGPDYIIPKPFDSRLILRIAPAVAQAAEDSGVATRPITDMA
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHH
AYRQELSRFVYSTGMLMQPVFNAARAIPDAHKRVAFAEGEDDRVLRAAQLVLDEGLARPI
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCEEECCCCCHHHHHHHHHHHHCCCCCCE
LIGRPAVIETRIAKAGLRLRLGDDVECVNPEDDPRFRHYWETYHRIMGRHGVTPEAAKAA
EECCCHHHHHHHHHCCCEEEECCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
VRRSTTTIAALMVKLGDADAMLCGMVGRYDGHLEHVRDIIGLKEDASGFAALNALMLDKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
TLFIADTFVNEDPSAEQLASIALMAVDEVRRFGIPPKVAFLSHSNYGSSNRASARKMRLA
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHH
HELFARMAPDVESDGELHGDAALSEEVRRASLMESNMSGEANILICPNLDSANILFNVLK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
MTGGQGVTVGPILLGTAASAHILTTSATVRRVVNMTALAVASAAARR
HCCCCCCEECHHHEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]