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The map label for this gene is gutB [H]

Identifier: 91787182

GI number: 91787182

Start: 1327840

End: 1328880

Strand: Reverse

Name: gutB [H]

Synonym: Bpro_1286

Alternate gene names: 91787182

Gene position: 1328880-1327840 (Counterclockwise)

Preceding gene: 91787183

Following gene: 91787181

Centisome position: 25.55

GC content: 62.73

Gene sequence:

>1041_bases
ATGAAAGCCGCCGTTCTGCGCGCCCCCAAGGTACTGCAACTCAGCGACATCGCCACACCGGAAGCCGCACCCGGCGAGCT
GGTGCTGCGTGTGCGGGCTGCGATGGTCTGCGGGACGGATCTGCGAATTTTGACTGGCCGAAAGACCAAGGGGGTACGTT
TTCCCTCGGTCATCGGACACGAGTTTGCGGGCGAAGTGGTTCAGGTCGGCGACGGCGTGACTCAGTTCAAGACGGGAGAC
CGTGTCTGCATGGATCCCGTCATCCCCTGCCGGGCCTGCGCCTATTGCAAGACCGGGCACGAAAATGTCTGCCTTCATCG
GCAGGCCATGGGCTATGAATTCGACGGCGCTTTTGCCGAGTACATCCGTATTCCGGCGATCGCGCTCACGGCGGGAAATG
TGTTCATGATGCCCGCGCAGATGAGCTTTGAATCCGCCGCACTCGCCGAGCCCCTGGCCTGCTGCATCAACGGCCAGCGC
AATGCCGGTGTCCAGGTCGGAGATACCGTGGTGGTCCTCGGAGCCGGCCCCATCGGCCTGATGCACGCCGCGCTGGCGCG
TCTCTCGGGAGCCAGGCAGGTGATTGTCAGCGAGCCCAATGCGGCGCGGCGCCAGGCTGCCGTCGACCGGGGCGTTGAAC
ATATGTGCGACCCCAGCACCGAGTCTGTCATGGAGTTTGTCAAGGCCCGCACCGACGGACTCGGCGCGGATGTTGTGATT
CTCGCCATTGGCGTCCCGCAGCTTGCCAATGAATCGCTCAATCTGGTCCGCAAGGGGGGACACGTCAACCTCTTTGCGGG
TTTCTCGGCCGGTGAGACCTCGAACATCGATGTCAACCTGATCCACTACAACGAAATCGTGGTCACGGGCGCCAGTGCCC
TGAGGCGACGCGACTACGAACTTGCGCTGAACATGCTGTCAGCCGGTCAGATCGACGCCAATTCGCTGATCACCCATCGC
TACGAGGTCGCGGATTCGCTGGCAGCCTTTGACGAAGCCGGCAGCGGCCGGGCCCTGAAGGTGGCGATTCACAATGTCTG
A

Upstream 100 bases:

>100_bases
CCACGGCCGTGATCCGTTCCCTCAGCGCCCTGATTCACGACAACGCCAGCGTGGCAGAAGCCCTCAAGGTCTATGACGCC
GCAGTGACGACGGAGGCCGA

Downstream 100 bases:

>100_bases
AGTCCTGCTCGGCATCGATGCCGGTACCAGCGCCATCAAGGTCTGCGCCTTCGACCCGGGTGGCAAGCTGCTGGCCAAGG
CCCAGCGTTCGGTGCCCGTC

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: Glucitol dehydrogenase; L-iditol 2-dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKAAVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKGVRFPSVIGHEFAGEVVQVGDGVTQFKTGD
RVCMDPVIPCRACAYCKTGHENVCLHRQAMGYEFDGAFAEYIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQR
NAGVQVGDTVVVLGAGPIGLMHAALARLSGARQVIVSEPNAARRQAAVDRGVEHMCDPSTESVMEFVKARTDGLGADVVI
LAIGVPQLANESLNLVRKGGHVNLFAGFSAGETSNIDVNLIHYNEIVVTGASALRRRDYELALNMLSAGQIDANSLITHR
YEVADSLAAFDEAGSGRALKVAIHNV

Sequences:

>Translated_346_residues
MKAAVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKGVRFPSVIGHEFAGEVVQVGDGVTQFKTGD
RVCMDPVIPCRACAYCKTGHENVCLHRQAMGYEFDGAFAEYIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQR
NAGVQVGDTVVVLGAGPIGLMHAALARLSGARQVIVSEPNAARRQAAVDRGVEHMCDPSTESVMEFVKARTDGLGADVVI
LAIGVPQLANESLNLVRKGGHVNLFAGFSAGETSNIDVNLIHYNEIVVTGASALRRRDYELALNMLSAGQIDANSLITHR
YEVADSLAAFDEAGSGRALKVAIHNV
>Mature_346_residues
MKAAVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKGVRFPSVIGHEFAGEVVQVGDGVTQFKTGD
RVCMDPVIPCRACAYCKTGHENVCLHRQAMGYEFDGAFAEYIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQR
NAGVQVGDTVVVLGAGPIGLMHAALARLSGARQVIVSEPNAARRQAAVDRGVEHMCDPSTESVMEFVKARTDGLGADVVI
LAIGVPQLANESLNLVRKGGHVNLFAGFSAGETSNIDVNLIHYNEIVVTGASALRRRDYELALNMLSAGQIDANSLITHR
YEVADSLAAFDEAGSGRALKVAIHNV

Specific function: Reduces glucitol to fructose [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=348, Percent_Identity=29.5977011494253, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4501939, Length=268, Percent_Identity=27.2388059701493, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI156523966, Length=268, Percent_Identity=27.2388059701493, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4501929, Length=369, Percent_Identity=24.9322493224932, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI71565154, Length=282, Percent_Identity=25.886524822695, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1790045, Length=346, Percent_Identity=30.0578034682081, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI226510992, Length=325, Percent_Identity=31.3846153846154, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787863, Length=336, Percent_Identity=30.0595238095238, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788073, Length=335, Percent_Identity=27.4626865671642, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786825, Length=273, Percent_Identity=31.8681318681319, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788075, Length=345, Percent_Identity=27.536231884058, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788407, Length=340, Percent_Identity=26.4705882352941, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082125, Length=358, Percent_Identity=24.8603351955307, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994910, Length=360, Percent_Identity=26.1111111111111, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790718, Length=341, Percent_Identity=24.3401759530792, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786552, Length=373, Percent_Identity=26.5415549597855, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=25.5192878338279, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562878, Length=350, Percent_Identity=29.1428571428571, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17562876, Length=349, Percent_Identity=28.080229226361, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71997431, Length=373, Percent_Identity=25.201072386059, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=373, Percent_Identity=25.4691689008043, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562584, Length=306, Percent_Identity=28.1045751633987, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=320, Percent_Identity=25.3125, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562582, Length=304, Percent_Identity=24.6710526315789, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565904, Length=355, Percent_Identity=26.7605633802817, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=340, Percent_Identity=28.5294117647059, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6322619, Length=323, Percent_Identity=30.3405572755418, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6319955, Length=323, Percent_Identity=30.3405572755418, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6319257, Length=340, Percent_Identity=29.7058823529412, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319258, Length=346, Percent_Identity=28.3236994219653, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6320033, Length=378, Percent_Identity=25.1322751322751, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=311, Percent_Identity=28.2958199356913, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=311, Percent_Identity=27.6527331189711, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=310, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=309, Percent_Identity=27.5080906148867, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737897, Length=351, Percent_Identity=33.048433048433, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17137530, Length=354, Percent_Identity=31.0734463276836, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17737895, Length=292, Percent_Identity=28.7671232876712, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.14 [H]

Molecular weight: Translated: 36636; Mature: 36636

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKGVRFPSVIGH
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHH
EFAGEVVQVGDGVTQFKTGDRVCMDPVIPCRACAYCKTGHENVCLHRQAMGYEFDGAFAE
HHHCCCEECCCCCEEECCCCEEECCCCCHHHHHHHHCCCCCCEEEEHHHCCEECCCHHHH
YIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQRNAGVQVGDTVVVLGAGPIGL
HHHCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCHHH
MHAALARLSGARQVIVSEPNAARRQAAVDRGVEHMCDPSTESVMEFVKARTDGLGADVVI
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCEEE
LAIGVPQLANESLNLVRKGGHVNLFAGFSAGETSNIDVNLIHYNEIVVTGASALRRRDYE
EEECCHHHCCCHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECEEEEECHHHHHHCCHH
LALNMLSAGQIDANSLITHRYEVADSLAAFDEAGSGRALKVAIHNV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MKAAVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKGVRFPSVIGH
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHH
EFAGEVVQVGDGVTQFKTGDRVCMDPVIPCRACAYCKTGHENVCLHRQAMGYEFDGAFAE
HHHCCCEECCCCCEEECCCCEEECCCCCHHHHHHHHCCCCCCEEEEHHHCCEECCCHHHH
YIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQRNAGVQVGDTVVVLGAGPIGL
HHHCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCHHH
MHAALARLSGARQVIVSEPNAARRQAAVDRGVEHMCDPSTESVMEFVKARTDGLGADVVI
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCEEE
LAIGVPQLANESLNLVRKGGHVNLFAGFSAGETSNIDVNLIHYNEIVVTGASALRRRDYE
EEECCHHHCCCHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECEEEEECHHHHHHCCHH
LALNMLSAGQIDANSLITHRYEVADSLAAFDEAGSGRALKVAIHNV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086842; 11058132 [H]