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The map label for this gene is hutU [H]

Identifier: 91787061

GI number: 91787061

Start: 1206144

End: 1207862

Strand: Reverse

Name: hutU [H]

Synonym: Bpro_1164

Alternate gene names: 91787061

Gene position: 1207862-1206144 (Counterclockwise)

Preceding gene: 91787079

Following gene: 91787060

Centisome position: 23.23

GC content: 66.38

Gene sequence:

>1719_bases
ATGTCGGATCTCATGCCGGATCTTTCCAACACCCCCTTCCAGGACAGCCAGGCCCGACCGGTCCGCGCGCCCCGGGGAAG
CGCCCTCACCTGCGCCAACTGGCAGATCGAAGCGGCTTACCGCATGATCCAGAACAACCTGGACCCGGAAGTCGCGGAAA
ACCCCGACGAGCTGGTGGTGTACGGCGGCATTGGCAAGGCGGCGCGCAACTGGCCGGCGTTTGACGCCATCCTGGACTCG
CTGCGCAAGCTCAAGGCCGACGAGACACTGCTGGTGCAGTCCGGCAAGCCGGTCGGCGTGTTCCGCACCCATGCGGGCGC
GCCGCGCGTGCTGATCGCCAATTCCAACCTGGTGCCCAAATGGGCCACCTGGGAACACTTCAATGAACTCGACCGCGCCG
GCCTCATGATGTACGGCCAGATGACGGCCGGCAGCTGGATCTACATCGGCACGCAGGGCATCGTGCAGGGCACGTACGAG
ACCTTTGTGGAAGCGGGCCGCCAGCACTTCAATGGCGACCTGGCGGGCCGCTGGGTGCTGACGGCGGGGTTGGGGGGCAT
GGGTGGCGCGCAGCCGCTGGCGGCGACCTTTGCCGGCGCCTGCTCCCTCAACATCGAATGCCAGCAGTCGCGCATCGACT
TTCGCTTGAGGACGCGCTACGTCGACAAGCAAGCCGCCAGCCTCGACGAAGCGCTGGAGATGATCCAGCACCACACGTCG
CGCAAGGAGGCCGTCTCCATCGCGCTGTGCGGCAATGCGGCCGAGATCGTGCCGGAACTGGTCAGGCGCGCGCAGGCCGG
CGGCATCCGCCCCGACATCGTGACCGACCAGACCTCGGCCCACGACATCATCAATGGCTACCTGCCGGCGGGCTGGACGG
TGGCCCGATGGCAGGCCGCGCAAAAGGACCCGGCGCAGCATGCCGCGCTGACAAAAGCGGCCGGCGAGTCCTGCGCGGTG
CACGTCAAGGCCATGCTGGCTTTCCATGAAATGGGCATTCCCACCGTGGACTACGGCAACAACCTGCGCCAGGTCGCCAA
GGACTTCGGCGTGGCCAATGCCTTTGACTACCCCGGTTTTGTGCCCGCCTACATCCGGCCGCTGTTTTGCCGCGGTGTCG
GGCCCTTCCGCTGGGTGGCGCTGTCGGGCGATCCGGAGGACATTCGCAAGACCGATGCGAAGATGAAGGAACTGTTCCCC
GACAACACGCCCCTGCACCGCTGGCTTGACATGGCCGAAGAGCGCATCAGCTTCCAGGGCCTGCCGGCGCGCATTTGCTG
GATTGGCCTGGGCGAACGCCATAGGGCGGGCCTGGCTTTCAACGAGATGGTGAAAAGCGGCGAGCTGAAGGCGCCCATCG
TCATCGGCCGCGACCACCTCGACAGCGGCTCCGTCGCTTCGCCGAACCGTGAAACCGAGGCGATGCAGGACGGCAGCGAT
GCCGTGAGCGACTGGCCGCTGCTCAATGCCCTGCTCAACACGGCCAGCGGCGCCACCTGGGTCAGCCTGCACCATGGCGG
CGGCGTGGGCATGGGTTACTCGCAGCACGCGGGCGTGGTCATTGTGTGTGACGGTACCCTTGAGGCGGCTGAACGCATCG
AACGCGTGCTGTTCAATGACCCGGCCACCGGCGTCATGCGCCATGCGGATGCGGGCTATGAGATCGCCCGCCAGAGCGCC
CGAGACAACCACCTGAACCTGCCCATGATGGGAGCCTGA

Upstream 100 bases:

>100_bases
ACAAGTTGTATAGACAACTACGATTTAACCAACCAAAGCCTGAAGCCCGAGCCCGAAGCCGCGCCAAAGTTTTTTCTTTT
TGTTACATGGAGCCTGTCTC

Downstream 100 bases:

>100_bases
AACATGTCCGACCATAACGTTGACGATACGGCCGAAATCTACCTGACCTATCTGAACCACCCTGACGTGCAGGCATTGGC
CCTGACCGATGCCGAAATCA

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MSDLMPDLSNTPFQDSQARPVRAPRGSALTCANWQIEAAYRMIQNNLDPEVAENPDELVVYGGIGKAARNWPAFDAILDS
LRKLKADETLLVQSGKPVGVFRTHAGAPRVLIANSNLVPKWATWEHFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTYE
TFVEAGRQHFNGDLAGRWVLTAGLGGMGGAQPLAATFAGACSLNIECQQSRIDFRLRTRYVDKQAASLDEALEMIQHHTS
RKEAVSIALCGNAAEIVPELVRRAQAGGIRPDIVTDQTSAHDIINGYLPAGWTVARWQAAQKDPAQHAALTKAAGESCAV
HVKAMLAFHEMGIPTVDYGNNLRQVAKDFGVANAFDYPGFVPAYIRPLFCRGVGPFRWVALSGDPEDIRKTDAKMKELFP
DNTPLHRWLDMAEERISFQGLPARICWIGLGERHRAGLAFNEMVKSGELKAPIVIGRDHLDSGSVASPNRETEAMQDGSD
AVSDWPLLNALLNTASGATWVSLHHGGGVGMGYSQHAGVVIVCDGTLEAAERIERVLFNDPATGVMRHADAGYEIARQSA
RDNHLNLPMMGA

Sequences:

>Translated_572_residues
MSDLMPDLSNTPFQDSQARPVRAPRGSALTCANWQIEAAYRMIQNNLDPEVAENPDELVVYGGIGKAARNWPAFDAILDS
LRKLKADETLLVQSGKPVGVFRTHAGAPRVLIANSNLVPKWATWEHFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTYE
TFVEAGRQHFNGDLAGRWVLTAGLGGMGGAQPLAATFAGACSLNIECQQSRIDFRLRTRYVDKQAASLDEALEMIQHHTS
RKEAVSIALCGNAAEIVPELVRRAQAGGIRPDIVTDQTSAHDIINGYLPAGWTVARWQAAQKDPAQHAALTKAAGESCAV
HVKAMLAFHEMGIPTVDYGNNLRQVAKDFGVANAFDYPGFVPAYIRPLFCRGVGPFRWVALSGDPEDIRKTDAKMKELFP
DNTPLHRWLDMAEERISFQGLPARICWIGLGERHRAGLAFNEMVKSGELKAPIVIGRDHLDSGSVASPNRETEAMQDGSD
AVSDWPLLNALLNTASGATWVSLHHGGGVGMGYSQHAGVVIVCDGTLEAAERIERVLFNDPATGVMRHADAGYEIARQSA
RDNHLNLPMMGA
>Mature_571_residues
SDLMPDLSNTPFQDSQARPVRAPRGSALTCANWQIEAAYRMIQNNLDPEVAENPDELVVYGGIGKAARNWPAFDAILDSL
RKLKADETLLVQSGKPVGVFRTHAGAPRVLIANSNLVPKWATWEHFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTYET
FVEAGRQHFNGDLAGRWVLTAGLGGMGGAQPLAATFAGACSLNIECQQSRIDFRLRTRYVDKQAASLDEALEMIQHHTSR
KEAVSIALCGNAAEIVPELVRRAQAGGIRPDIVTDQTSAHDIINGYLPAGWTVARWQAAQKDPAQHAALTKAAGESCAVH
VKAMLAFHEMGIPTVDYGNNLRQVAKDFGVANAFDYPGFVPAYIRPLFCRGVGPFRWVALSGDPEDIRKTDAKMKELFPD
NTPLHRWLDMAEERISFQGLPARICWIGLGERHRAGLAFNEMVKSGELKAPIVIGRDHLDSGSVASPNRETEAMQDGSDA
VSDWPLLNALLNTASGATWVSLHHGGGVGMGYSQHAGVVIVCDGTLEAAERIERVLFNDPATGVMRHADAGYEIARQSAR
DNHLNLPMMGA

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=562, Percent_Identity=34.8754448398576, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI260306182, Length=207, Percent_Identity=39.6135265700483, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71997891, Length=566, Percent_Identity=35.8657243816254, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 62185; Mature: 62054

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLMPDLSNTPFQDSQARPVRAPRGSALTCANWQIEAAYRMIQNNLDPEVAENPDELVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHCCCCCEEE
YGGIGKAARNWPAFDAILDSLRKLKADETLLVQSGKPVGVFRTHAGAPRVLIANSNLVPK
ECCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCCCC
WATWEHFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTYETFVEAGRQHFNGDLAGRWVL
CCCHHHHHHHHHCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TAGLGGMGGAQPLAATFAGACSLNIECQQSRIDFRLRTRYVDKQAASLDEALEMIQHHTS
EECCCCCCCCCHHHHHHHCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
RKEAVSIALCGNAAEIVPELVRRAQAGGIRPDIVTDQTSAHDIINGYLPAGWTVARWQAA
HHHEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCEEHHHHHH
QKDPAQHAALTKAAGESCAVHVKAMLAFHEMGIPTVDYGNNLRQVAKDFGVANAFDYPGF
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
VPAYIRPLFCRGVGPFRWVALSGDPEDIRKTDAKMKELFPDNTPLHRWLDMAEERISFQG
CHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
LPARICWIGLGERHRAGLAFNEMVKSGELKAPIVIGRDHLDSGSVASPNRETEAMQDGSD
CCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCC
AVSDWPLLNALLNTASGATWVSLHHGGGVGMGYSQHAGVVIVCDGTLEAAERIERVLFND
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
PATGVMRHADAGYEIARQSARDNHLNLPMMGA
CCHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDLMPDLSNTPFQDSQARPVRAPRGSALTCANWQIEAAYRMIQNNLDPEVAENPDELVV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHCCCCCEEE
YGGIGKAARNWPAFDAILDSLRKLKADETLLVQSGKPVGVFRTHAGAPRVLIANSNLVPK
ECCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCCCC
WATWEHFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTYETFVEAGRQHFNGDLAGRWVL
CCCHHHHHHHHHCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TAGLGGMGGAQPLAATFAGACSLNIECQQSRIDFRLRTRYVDKQAASLDEALEMIQHHTS
EECCCCCCCCCHHHHHHHCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
RKEAVSIALCGNAAEIVPELVRRAQAGGIRPDIVTDQTSAHDIINGYLPAGWTVARWQAA
HHHEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCEEHHHHHH
QKDPAQHAALTKAAGESCAVHVKAMLAFHEMGIPTVDYGNNLRQVAKDFGVANAFDYPGF
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
VPAYIRPLFCRGVGPFRWVALSGDPEDIRKTDAKMKELFPDNTPLHRWLDMAEERISFQG
CHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
LPARICWIGLGERHRAGLAFNEMVKSGELKAPIVIGRDHLDSGSVASPNRETEAMQDGSD
CCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCC
AVSDWPLLNALLNTASGATWVSLHHGGGVGMGYSQHAGVVIVCDGTLEAAERIERVLFND
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
PATGVMRHADAGYEIARQSARDNHLNLPMMGA
CCHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]