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The map label for this gene is thiD [C]

Identifier: 91787032

GI number: 91787032

Start: 1172806

End: 1173813

Strand: Reverse

Name: thiD [C]

Synonym: Bpro_1134

Alternate gene names: 91787032

Gene position: 1173813-1172806 (Counterclockwise)

Preceding gene: 91787045

Following gene: 91787031

Centisome position: 22.57

GC content: 61.11

Gene sequence:

>1008_bases
ATGCGGCGTTGCTTATTCGCGTACAAGGCAAAATCGCAGCCTATGGCAAACCCCAACACCTCTTCACTGGACAGCCGGCA
ACTGCAAACCGAGGACAGCGACGCGTCTCCGGCATGCGTCATGACCTTCAATGCCAATGATCCGAGCGGAGCAGGTGGAC
TGACGGCCGACATCGCAGCGATCACCTCGGCGGGGGCTCATCCACTGGCTGTCGTCACCGGCGCGTACGTGCGCGACACC
GCCGAGATTTTTGACCATTTCTCATTCGACGAAGAGGCTGTCACCGACCAGGCGCGATCCGCACTCGAAGACATGCCGGT
GTCGGCCATCAAGGTCGGTTTTGTCGGCAGCCCGGAGAACATCAGCACCATCGCCGAGATCGCGACCGACTATGCCGATG
TACCGCTTATCGCTTACATGCCCAACCTGTCATGGTGGGACGAAAGCGAAATTGACAGCTACCTCGATGCCTTTCGTGAG
TTGATGCTGCCGCAGACGACAGTGTTGGTCGGCAACCACAGCAGCCTGTGGCGCTGGTTGCTGCCGGACTGGCCGGGCGA
GCGCAACCCCTCGGCTCGCGACATTGCCAAGGCTGCGGCCGACCTGGGCGTGCCCTACACGCTGGTGACCGGCATTCCCC
TGCCCGACCAGTTCATCGACAACGTGCTGGCGACTCCGCAAGCCGTTTTGTACAGTGAAAAATTCGAGCGCTTTGAGGCG
GTATTTGCCGGCGCCGGCGAAACGCTGTCTGCCGCACTCTCGGCCCTGCTGGCCAATGGCCACGATCTGCAGGCGGCCAC
CGCCGAAGCCCTGACCTATCTGGACCACAGCCTGGATGCCGGTTTTCACCCCGGCATGGGCAACATCGTGCCTGACCGCC
TGTTCTGGGCGCAGGCCGATGTCGATGATGAAGAATCCGAAGACGAAGCGGGCGACACGCCCGACGATGCCGCACTGACA
TCCAAGCCTCCTTTTGACCTGCCGCCCAATGGAACCACAAAACATTAA

Upstream 100 bases:

>100_bases
AGCAGCTTCATCATAAATCCACCCACAGATCAAACACATCCACGTCATTGATTGAGTCACAGCTTAAGTTGCCTTCGAAT
AGAATGCAACAATTGTATCG

Downstream 100 bases:

>100_bases
GCCCCACACCCCCGAGCTCTCCCGCAACACCGCGCTGTTCGAGCGCGCCAAAAAGTTGATCCCCGGCGGGGTGAATTCGC
CGGTCAGGGCGTTCAAGGCC

Product: putative phosphomethylpyrimidine kinase

Products: ADP; 4-amino-5-phosphomethyl-2-methylpyrimidine

Alternate protein names: Hydroxymethylpyrimidine Kinase; Hydroxymethylpyrimidine/Phosphomethylpyrimidine Kinase; Phosphomethylpyrimidine Kinase Family Protein; Bifunctional ThiED Protein; Bifunctional Thiamine Biosynthesis ThiD; Adenine Phosphoribosyltransferase; Phosphomethylpyrimidine Kinase Superfamily

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRRCLFAYKAKSQPMANPNTSSLDSRQLQTEDSDASPACVMTFNANDPSGAGGLTADIAAITSAGAHPLAVVTGAYVRDT
AEIFDHFSFDEEAVTDQARSALEDMPVSAIKVGFVGSPENISTIAEIATDYADVPLIAYMPNLSWWDESEIDSYLDAFRE
LMLPQTTVLVGNHSSLWRWLLPDWPGERNPSARDIAKAAADLGVPYTLVTGIPLPDQFIDNVLATPQAVLYSEKFERFEA
VFAGAGETLSAALSALLANGHDLQAATAEALTYLDHSLDAGFHPGMGNIVPDRLFWAQADVDDEESEDEAGDTPDDAALT
SKPPFDLPPNGTTKH

Sequences:

>Translated_335_residues
MRRCLFAYKAKSQPMANPNTSSLDSRQLQTEDSDASPACVMTFNANDPSGAGGLTADIAAITSAGAHPLAVVTGAYVRDT
AEIFDHFSFDEEAVTDQARSALEDMPVSAIKVGFVGSPENISTIAEIATDYADVPLIAYMPNLSWWDESEIDSYLDAFRE
LMLPQTTVLVGNHSSLWRWLLPDWPGERNPSARDIAKAAADLGVPYTLVTGIPLPDQFIDNVLATPQAVLYSEKFERFEA
VFAGAGETLSAALSALLANGHDLQAATAEALTYLDHSLDAGFHPGMGNIVPDRLFWAQADVDDEESEDEAGDTPDDAALT
SKPPFDLPPNGTTKH
>Mature_335_residues
MRRCLFAYKAKSQPMANPNTSSLDSRQLQTEDSDASPACVMTFNANDPSGAGGLTADIAAITSAGAHPLAVVTGAYVRDT
AEIFDHFSFDEEAVTDQARSALEDMPVSAIKVGFVGSPENISTIAEIATDYADVPLIAYMPNLSWWDESEIDSYLDAFRE
LMLPQTTVLVGNHSSLWRWLLPDWPGERNPSARDIAKAAADLGVPYTLVTGIPLPDQFIDNVLATPQAVLYSEKFERFEA
VFAGAGETLSAALSALLANGHDLQAATAEALTYLDHSLDAGFHPGMGNIVPDRLFWAQADVDDEESEDEAGDTPDDAALT
SKPPFDLPPNGTTKH

Specific function: Catalyzes The Phosphorylation Of Hmp-P To Hmp-Pp. [C]

COG id: COG0351

COG function: function code H; Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.49; 2.7.4.7

Molecular weight: Translated: 35980; Mature: 35980

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRCLFAYKAKSQPMANPNTSSLDSRQLQTEDSDASPACVMTFNANDPSGAGGLTADIAA
CCCEEEEHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
ITSAGAHPLAVVTGAYVRDTAEIFDHFSFDEEAVTDQARSALEDMPVSAIKVGFVGSPEN
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
ISTIAEIATDYADVPLIAYMPNLSWWDESEIDSYLDAFRELMLPQTTVLVGNHSSLWRWL
HHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHC
LPDWPGERNPSARDIAKAAADLGVPYTLVTGIPLPDQFIDNVLATPQAVLYSEKFERFEA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
VFAGAGETLSAALSALLANGHDLQAATAEALTYLDHSLDAGFHPGMGNIVPDRLFWAQAD
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECC
VDDEESEDEAGDTPDDAALTSKPPFDLPPNGTTKH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRCLFAYKAKSQPMANPNTSSLDSRQLQTEDSDASPACVMTFNANDPSGAGGLTADIAA
CCCEEEEHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
ITSAGAHPLAVVTGAYVRDTAEIFDHFSFDEEAVTDQARSALEDMPVSAIKVGFVGSPEN
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
ISTIAEIATDYADVPLIAYMPNLSWWDESEIDSYLDAFRELMLPQTTVLVGNHSSLWRWL
HHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHC
LPDWPGERNPSARDIAKAAADLGVPYTLVTGIPLPDQFIDNVLATPQAVLYSEKFERFEA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
VFAGAGETLSAALSALLANGHDLQAATAEALTYLDHSLDAGFHPGMGNIVPDRLFWAQAD
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECC
VDDEESEDEAGDTPDDAALTSKPPFDLPPNGTTKH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 4-amino-5-hydroxymethyl-2-methylpyrimidine

Specific reaction: ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-5-phosphomethyl-2-methylpyrimidine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA