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The map label for this gene is groES

Identifier: 91786662

GI number: 91786662

Start: 779599

End: 779889

Strand: Reverse

Name: groES

Synonym: Bpro_0760

Alternate gene names: 91786662

Gene position: 779889-779599 (Counterclockwise)

Preceding gene: 91786668

Following gene: 91786661

Centisome position: 15.0

GC content: 55.67

Gene sequence:

>291_bases
ATGAAACTTCGTCCTTTGCACGACCGCGTGATCGTCAAACGCGTGGAAAACGAAACCAAAACCGCCTCTGGCATCGTCAT
TCCTGACAGCGCCGCTGAAAAGCCTGATCAGGGCGAAGTCCTGGCCGTGGGCCCAGGCAAGAAAAACGACAAGGGCGATT
TGAGCCCTATGGCCGTCAAGATCGGTGACCGCGTGCTGTTTGGCAAATACAGCGGCCAGACCGTCAAGGTCGACGGCGAC
GAGCTGCTCGTGATGAAAGAAGAAGACCTGTTTGCGGTCGTTGAGAAGTAA

Upstream 100 bases:

>100_bases
TGCTAACAAAGCGTATTCAAGCCACCAAGTTAACAAGCACCCACTTCTGTTGGGTGCTTTTTGATTCTCAAAAACCATTG
TCCTCAAACAAGGAGCTCTC

Downstream 100 bases:

>100_bases
TTTCTCGGCTCTTTCAATCCCTCATTAACTGAATCTGGAGAATTAAACATGGCAGCAAAAGACGTCATTTTCGGCGGCGA
AGCCCGCGCACGCATGGTCG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKLRPLHDRVIVKRVENETKTASGIVIPDSAAEKPDQGEVLAVGPGKKNDKGDLSPMAVKIGDRVLFGKYSGQTVKVDGD
ELLVMKEEDLFAVVEK

Sequences:

>Translated_96_residues
MKLRPLHDRVIVKRVENETKTASGIVIPDSAAEKPDQGEVLAVGPGKKNDKGDLSPMAVKIGDRVLFGKYSGQTVKVDGD
ELLVMKEEDLFAVVEK
>Mature_96_residues
MKLRPLHDRVIVKRVENETKTASGIVIPDSAAEKPDQGEVLAVGPGKKNDKGDLSPMAVKIGDRVLFGKYSGQTVKVDGD
ELLVMKEEDLFAVVEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=53.125, Blast_Score=100, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=42.8571428571429, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324594, Length=93, Percent_Identity=39.7849462365591, Blast_Score=75, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=44.3298969072165, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358317, Length=97, Percent_Identity=43.298969072165, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_POLSJ (Q12FH6)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547614.1
- ProteinModelPortal:   Q12FH6
- SMR:   Q12FH6
- STRING:   Q12FH6
- GeneID:   4011181
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_0760
- NMPDR:   fig|296591.1.peg.3173
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   RVIYARY
- PhylomeDB:   Q12FH6
- ProtClustDB:   PRK00364
- BioCyc:   PSP296591:BPRO_0760-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10446; Mature: 10446

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLHDRVIVKRVENETKTASGIVIPDSAAEKPDQGEVLAVGPGKKNDKGDLSPMAVK
CCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEE
IGDRVLFGKYSGQTVKVDGDELLVMKEEDLFAVVEK
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MKLRPLHDRVIVKRVENETKTASGIVIPDSAAEKPDQGEVLAVGPGKKNDKGDLSPMAVK
CCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEE
IGDRVLFGKYSGQTVKVDGDELLVMKEEDLFAVVEK
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA