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The map label for this gene is degS [H]

Identifier: 91786668

GI number: 91786668

Start: 785967

End: 787361

Strand: Reverse

Name: degS [H]

Synonym: Bpro_0766

Alternate gene names: 91786668

Gene position: 787361-785967 (Counterclockwise)

Preceding gene: 91786669

Following gene: 91786662

Centisome position: 15.14

GC content: 62.01

Gene sequence:

>1395_bases
ATGCAACGAATCACCAACCGGATGGCCATCAACATCGCCAGCTCGTTGATTGCCGTGTTCACCCTTATTGGCATCAGTGA
GCTGTCCTACCAAAAATCCATCCACGCGATGGATGACCTGTCCGAGGCGCATGTCACGCGCACCCATCTTCAGCGGCTGC
TGCGTGACGTGCTGGATGCCGAAACGGGCCAAAGGGGCTACCTGCTGACGGCGGACACCGCCTACCTGGAGCCTTACCGG
ACGGCGATTGCCGACCTCAGCCAGACGCAGGACCAGCTGGTCAATCTGTTTGCCAACAAGCCCGAACAGAGCGCCGCGCT
GGCCGTACTGGGCTGGACCGTGCAGCGCAAGCTGGCCGAAATGGACCTGTCCATCCGCATGAAAAATGAGGACAAGGAAG
ACGCCTGGAAGTTTGTCCTGACCACCGACGTGGGCAAAAAACAAATGGATGACATACGCGTCAGCTCCGCGCAATTGATC
GATGCGAGCCTGACGCAGACCACGCAGAGGCATGCGGACATCCGGCAGTCCCTGTTGCTGTCCCGGGTGGGCATCACGCT
GGTGGCCGCCGTGGGACTGATGGCGTTCTGGCTGTATTTGCGGCAGACCGCCGCGCTGAAACTGGCCGATCAGCATCAGC
AGGCCACGCTGCAGGCCGAACGCGACTTGCTGGACGCCCAGGTCCAGGAGCGCACTGAACGCCTGGCGGAACTGGCCACA
CACCTGCAACAAGTCCGGGAAGACGAGCGGGCGCATCTGGCGCGGGAGCTTCATGACGAACTGGGTGCGCTGCTTACCGC
GGCCAAGCTGGATGTCGCCCGTATCAAGGCCAAATTGAGCGGCGACGCGAGCGACCTGCAGGCGCGCATCCAGCATCTGG
TTGAAACACTCAACAGCGGCATTGCGCTCAAGCGGCGCATCATTGAAGATCTGCGCCCCTCCTCCCTGGCCACCCTGGGC
TTGCTACCGTCCCTGGAAATCCTGGCGGGCGAGTTTGGCCAGCGTTCCGGCCTGGCCATCACGACCGATCTTGAACCGGT
TGACCTGGATGAGCCAACGGAACTGACGGTGTACCGGATCACTCAGGAAGCGCTGACCAATATTGGCAAACACGCCGAAG
CGCAACACGTGGAAATTGCCGTGCTCAACTACAAGGCCCACGTCACCGTCACCGTGCGCGACGACGGCAAGGGGTTTGAC
CCGAAGGCAATAGGCGCTTCCAGCTATGGCCTGCTGGGAATGCGTCACCGGGTGGAGGCTTGCGGCGGCCGCCTCACCAT
AGAGTCGGTGGGCAGTACCACCATCCGGGCGGTGTTTCCCTCCGTATCCCGCAAAAAGCCCGAGCAGCCCGCCATGGCGG
ACGAAAGCGGCGCCGCCACAAAAAGCCCCAGCTAG

Upstream 100 bases:

>100_bases
TTTGAGCATCCGGCCGGACGGCACAACCCGCCCAGACGTGCGCAATCGCCTGGCCCGGATAGGTGACAGTGGCCGTCTCG
AGATCATCACGAAAGCCCAC

Downstream 100 bases:

>100_bases
ACCTGCGGTGCCGTCGCAGCTTCGATCGGCATACCGCATATCCTGCAACAGGAACGTCCCCTTGACCGGCGTGCGCGCCC
TGTCAAAGCGTGAGCGCAGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MQRITNRMAINIASSLIAVFTLIGISELSYQKSIHAMDDLSEAHVTRTHLQRLLRDVLDAETGQRGYLLTADTAYLEPYR
TAIADLSQTQDQLVNLFANKPEQSAALAVLGWTVQRKLAEMDLSIRMKNEDKEDAWKFVLTTDVGKKQMDDIRVSSAQLI
DASLTQTTQRHADIRQSLLLSRVGITLVAAVGLMAFWLYLRQTAALKLADQHQQATLQAERDLLDAQVQERTERLAELAT
HLQQVREDERAHLARELHDELGALLTAAKLDVARIKAKLSGDASDLQARIQHLVETLNSGIALKRRIIEDLRPSSLATLG
LLPSLEILAGEFGQRSGLAITTDLEPVDLDEPTELTVYRITQEALTNIGKHAEAQHVEIAVLNYKAHVTVTVRDDGKGFD
PKAIGASSYGLLGMRHRVEACGGRLTIESVGSTTIRAVFPSVSRKKPEQPAMADESGAATKSPS

Sequences:

>Translated_464_residues
MQRITNRMAINIASSLIAVFTLIGISELSYQKSIHAMDDLSEAHVTRTHLQRLLRDVLDAETGQRGYLLTADTAYLEPYR
TAIADLSQTQDQLVNLFANKPEQSAALAVLGWTVQRKLAEMDLSIRMKNEDKEDAWKFVLTTDVGKKQMDDIRVSSAQLI
DASLTQTTQRHADIRQSLLLSRVGITLVAAVGLMAFWLYLRQTAALKLADQHQQATLQAERDLLDAQVQERTERLAELAT
HLQQVREDERAHLARELHDELGALLTAAKLDVARIKAKLSGDASDLQARIQHLVETLNSGIALKRRIIEDLRPSSLATLG
LLPSLEILAGEFGQRSGLAITTDLEPVDLDEPTELTVYRITQEALTNIGKHAEAQHVEIAVLNYKAHVTVTVRDDGKGFD
PKAIGASSYGLLGMRHRVEACGGRLTIESVGSTTIRAVFPSVSRKKPEQPAMADESGAATKSPS
>Mature_464_residues
MQRITNRMAINIASSLIAVFTLIGISELSYQKSIHAMDDLSEAHVTRTHLQRLLRDVLDAETGQRGYLLTADTAYLEPYR
TAIADLSQTQDQLVNLFANKPEQSAALAVLGWTVQRKLAEMDLSIRMKNEDKEDAWKFVLTTDVGKKQMDDIRVSSAQLI
DASLTQTTQRHADIRQSLLLSRVGITLVAAVGLMAFWLYLRQTAALKLADQHQQATLQAERDLLDAQVQERTERLAELAT
HLQQVREDERAHLARELHDELGALLTAAKLDVARIKAKLSGDASDLQARIQHLVETLNSGIALKRRIIEDLRPSSLATLG
LLPSLEILAGEFGQRSGLAITTDLEPVDLDEPTELTVYRITQEALTNIGKHAEAQHVEIAVLNYKAHVTVTVRDDGKGFD
PKAIGASSYGLLGMRHRVEACGGRLTIESVGSTTIRAVFPSVSRKKPEQPAMADESGAATKSPS

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=261, Percent_Identity=29.8850574712644, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87082311, Length=230, Percent_Identity=31.304347826087, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788812, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51084; Mature: 51084

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRITNRMAINIASSLIAVFTLIGISELSYQKSIHAMDDLSEAHVTRTHLQRLLRDVLDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETGQRGYLLTADTAYLEPYRTAIADLSQTQDQLVNLFANKPEQSAALAVLGWTVQRKLAE
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MDLSIRMKNEDKEDAWKFVLTTDVGKKQMDDIRVSSAQLIDASLTQTTQRHADIRQSLLL
CCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SRVGITLVAAVGLMAFWLYLRQTAALKLADQHQQATLQAERDLLDAQVQERTERLAELAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLQQVREDERAHLARELHDELGALLTAAKLDVARIKAKLSGDASDLQARIQHLVETLNSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
IALKRRIIEDLRPSSLATLGLLPSLEILAGEFGQRSGLAITTDLEPVDLDEPTELTVYRI
HHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCCCEEEEEE
TQEALTNIGKHAEAQHVEIAVLNYKAHVTVTVRDDGKGFDPKAIGASSYGLLGMRHRVEA
HHHHHHHHCCCCCCCEEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
CGGRLTIESVGSTTIRAVFPSVSRKKPEQPAMADESGAATKSPS
CCCEEEEECCCCHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQRITNRMAINIASSLIAVFTLIGISELSYQKSIHAMDDLSEAHVTRTHLQRLLRDVLDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETGQRGYLLTADTAYLEPYRTAIADLSQTQDQLVNLFANKPEQSAALAVLGWTVQRKLAE
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MDLSIRMKNEDKEDAWKFVLTTDVGKKQMDDIRVSSAQLIDASLTQTTQRHADIRQSLLL
CCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SRVGITLVAAVGLMAFWLYLRQTAALKLADQHQQATLQAERDLLDAQVQERTERLAELAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLQQVREDERAHLARELHDELGALLTAAKLDVARIKAKLSGDASDLQARIQHLVETLNSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
IALKRRIIEDLRPSSLATLGLLPSLEILAGEFGQRSGLAITTDLEPVDLDEPTELTVYRI
HHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCCCEEEEEE
TQEALTNIGKHAEAQHVEIAVLNYKAHVTVTVRDDGKGFDPKAIGASSYGLLGMRHRVEA
HHHHHHHHCCCCCCCEEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
CGGRLTIESVGSTTIRAVFPSVSRKKPEQPAMADESGAATKSPS
CCCEEEEECCCCHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]