Click here to switch to the map view.

The map label for this gene is coxS [H]

Identifier: 91786484

GI number: 91786484

Start: 581754

End: 582221

Strand: Reverse

Name: coxS [H]

Synonym: Bpro_0578

Alternate gene names: 91786484

Gene position: 582221-581754 (Counterclockwise)

Preceding gene: 91786485

Following gene: 91786483

Centisome position: 11.2

GC content: 63.03

Gene sequence:

>468_bases
ATGCAAGTTCAACTCACAGTCAACGGGAAATCGTCCAGCATTGAGGCCCCGCCCAACACCCTGTTGGTGCAGGTGTTGCG
GGAGCATCTCAAGCTCACCGGAACCCATGTGGGCTGCGACACCGCCCAATGCGGCGCCTGCACCGTCATCATGAACGGGC
GGGCCGTCAAGTCATGCAACATCCTGGCGGCCCAGGCGGCCGGTGCCGAGATCACCACCATTGAAGGCCTGGCCAAGGCA
GATGGCACGATGCACCCGATGCAGGCCGCCTTCAAGGAGTGCCACGGCCTGCAATGCGGTTTTTGCACCACCGGCATGGT
GATGAACGCCGTGGACCTGTGCACGCACCACCCCCAGGCCACGGAAGCCGAAATCCGCGAACTGCTGGAAGGCAATATCT
GCCGCTGCACGGGCTACCAGAACATCGTCAAGGCCGTGCAGCAAGGCGCGGTGGCGATGGCGACCTGA

Upstream 100 bases:

>100_bases
CGCATGCTAGGGTTTAACCTAGGGATGTCTGTCGTCAGTGATCCAACAATGAGCCTGCAACATCCTCAGCCAAAGCCAAT
AGCAGACAGGAGACTCGCCC

Downstream 100 bases:

>100_bases
GAGACCGGAGGCAACAGCACTGCCGGTTCCCGCTACCGGCATGGATGAAACGTCCCGCCAGCGCGAGAGCCAAGGCCAAA
CCAAGTTAGCCATCTTTCCC

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MQVQLTVNGKSSSIEAPPNTLLVQVLREHLKLTGTHVGCDTAQCGACTVIMNGRAVKSCNILAAQAAGAEITTIEGLAKA
DGTMHPMQAAFKECHGLQCGFCTTGMVMNAVDLCTHHPQATEAEIRELLEGNICRCTGYQNIVKAVQQGAVAMAT

Sequences:

>Translated_155_residues
MQVQLTVNGKSSSIEAPPNTLLVQVLREHLKLTGTHVGCDTAQCGACTVIMNGRAVKSCNILAAQAAGAEITTIEGLAKA
DGTMHPMQAAFKECHGLQCGFCTTGMVMNAVDLCTHHPQATEAEIRELLEGNICRCTGYQNIVKAVQQGAVAMAT
>Mature_155_residues
MQVQLTVNGKSSSIEAPPNTLLVQVLREHLKLTGTHVGCDTAQCGACTVIMNGRAVKSCNILAAQAAGAEITTIEGLAKA
DGTMHPMQAAFKECHGLQCGFCTTGMVMNAVDLCTHHPQATEAEIRELLEGNICRCTGYQNIVKAVQQGAVAMAT

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=156, Percent_Identity=36.5384615384615, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=37.5, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=46.6666666666667, Blast_Score=142, Evalue=8e-36,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=42.5675675675676, Blast_Score=109, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=40, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=35.9477124183007, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=35.2941176470588, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647197, Length=165, Percent_Identity=36.3636363636364, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647195, Length=165, Percent_Identity=36.3636363636364, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647201, Length=159, Percent_Identity=37.7358490566038, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647199, Length=159, Percent_Identity=37.7358490566038, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17737937, Length=154, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24647193, Length=165, Percent_Identity=34.5454545454545, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16284; Mature: 16284

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
11.0 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
11.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQLTVNGKSSSIEAPPNTLLVQVLREHLKLTGTHVGCDTAQCGACTVIMNGRAVKSCN
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECCCC
ILAAQAAGAEITTIEGLAKADGTMHPMQAAFKECHGLQCGFCTTGMVMNAVDLCTHHPQA
EEEECCCCCEEEEHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
TEAEIRELLEGNICRCTGYQNIVKAVQQGAVAMAT
CHHHHHHHHCCCCEEECCHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MQVQLTVNGKSSSIEAPPNTLLVQVLREHLKLTGTHVGCDTAQCGACTVIMNGRAVKSCN
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECCCC
ILAAQAAGAEITTIEGLAKADGTMHPMQAAFKECHGLQCGFCTTGMVMNAVDLCTHHPQA
EEEECCCCCEEEEHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
TEAEIRELLEGNICRCTGYQNIVKAVQQGAVAMAT
CHHHHHHHHCCCCEEECCHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]