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The map label for this gene is lrp [H]

Identifier: 91786309

GI number: 91786309

Start: 411090

End: 411569

Strand: Reverse

Name: lrp [H]

Synonym: Bpro_0399

Alternate gene names: 91786309

Gene position: 411569-411090 (Counterclockwise)

Preceding gene: 91786310

Following gene: 91786308

Centisome position: 7.91

GC content: 62.08

Gene sequence:

>480_bases
ATGAGCGAACCCCACATCGAGATCGACCGCATCGACCTGAAAATCCTGAATGTGCTGCAGCAGGATGGCCGGATTTCCAA
CCTCAAGCTGGCAGAAAGCGTGGCGCTGTCGCCCACCGCCGTGCTGGCGCGCGTGCAGCGGCTGACCCGCGACGGCTACA
TCCTGGGCTACGAAGCCCTGCTGAACCCGCTCAAGCTCGGCGCCGGCATGATGGTGTTTGTGGAAGTGCTGCTGGACCGC
ACCACGCCCAATGTGTTCGAAGCCTTCAAGGCGGCGGTGCAGGTGCACCACGAAATCATGGAATGCCACATGGTGGCCGG
CGGCTTTGATTACCTGCTCAAAACCCGCATGGCCGACATGGCCGCCTACCGCTCTTTTGCCGGCACCGTACTGTGGCAAT
TGCCCGGCGTGCGCGAGACTCGCACCTATGCGGTGATGGAAGAGGTGAAAAATACCACGCGGCTGGCGCTGGGCGTGTGA

Upstream 100 bases:

>100_bases
TCCACCTCGAAACCTACCGGATGACCTGAGAATGGCCGCATCCGCAACCCGCACCTCCACGCATGCGGCGGCAGCGCCTC
CCTTTGCCTGATTGACCTTC

Downstream 100 bases:

>100_bases
AGGTGACGGCGAGGGGTTGCAAACCGGTGCATGGTGGCAATAATGCGGGATCATGCGAGATCGCCCTCCAAACTTGTCTT
TTCAACAAGGATGCCCATGA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSEPHIEIDRIDLKILNVLQQDGRISNLKLAESVALSPTAVLARVQRLTRDGYILGYEALLNPLKLGAGMMVFVEVLLDR
TTPNVFEAFKAAVQVHHEIMECHMVAGGFDYLLKTRMADMAAYRSFAGTVLWQLPGVRETRTYAVMEEVKNTTRLALGV

Sequences:

>Translated_159_residues
MSEPHIEIDRIDLKILNVLQQDGRISNLKLAESVALSPTAVLARVQRLTRDGYILGYEALLNPLKLGAGMMVFVEVLLDR
TTPNVFEAFKAAVQVHHEIMECHMVAGGFDYLLKTRMADMAAYRSFAGTVLWQLPGVRETRTYAVMEEVKNTTRLALGV
>Mature_158_residues
SEPHIEIDRIDLKILNVLQQDGRISNLKLAESVALSPTAVLARVQRLTRDGYILGYEALLNPLKLGAGMMVFVEVLLDRT
TPNVFEAFKAAVQVHHEIMECHMVAGGFDYLLKTRMADMAAYRSFAGTVLWQLPGVRETRTYAVMEEVKNTTRLALGV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=154, Percent_Identity=59.0909090909091, Blast_Score=192, Evalue=9e-51,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=34.6666666666667, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17776; Mature: 17645

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPHIEIDRIDLKILNVLQQDGRISNLKLAESVALSPTAVLARVQRLTRDGYILGYEAL
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCEEEEHHHH
LNPLKLGAGMMVFVEVLLDRTTPNVFEAFKAAVQVHHEIMECHMVAGGFDYLLKTRMADM
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAYRSFAGTVLWQLPGVRETRTYAVMEEVKNTTRLALGV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEPHIEIDRIDLKILNVLQQDGRISNLKLAESVALSPTAVLARVQRLTRDGYILGYEAL
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCEEEEHHHH
LNPLKLGAGMMVFVEVLLDRTTPNVFEAFKAAVQVHHEIMECHMVAGGFDYLLKTRMADM
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAYRSFAGTVLWQLPGVRETRTYAVMEEVKNTTRLALGV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]