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The map label for this gene is csrD [H]

Identifier: 91786219

GI number: 91786219

Start: 331329

End: 333242

Strand: Reverse

Name: csrD [H]

Synonym: Bpro_0308

Alternate gene names: 91786219

Gene position: 333242-331329 (Counterclockwise)

Preceding gene: 91786220

Following gene: 91786218

Centisome position: 6.41

GC content: 65.31

Gene sequence:

>1914_bases
ATGTCCCTTATCAAACAGCTCTGGATCGCCATCATCGTGGTCATGACCATTGCCTTCGGCGGCAGCATGGTCGTCAGTGT
GTTGTCTGCACGCCACTACCTGGAGCAGCAGCTGCAAGTGAAGAACATCGACAACGCCACGGCGCTGGCCCTGTCGCTGT
CGCAGTTGCCCAAGGACCCAGTCACGGTCGAGCTGCAGGTGGCGACGCAGTTTGACGCCGGGCACTACCGCTTCATCCGC
ATCGTTTCGCCCACCGGCCAGACGGTGGTGGAGCGCGTCTTCACCGGTCAGCTGCAAGGCGCACCGGCCTGGTTCGCCCG
GCTCATCCCGATCCGCGCAGTGCCCGGCCAGGCGCTGATCCAGGATGGCTGGAAACAGTACGGAACGCTGACCCTGGCCA
GCCACGAGCAGTATGTGTACAAGAGCCTGTGGGACGGCACGCTGGAGCTGCTGCTGTGGTTTGTGCTCGGCAGCGTGATC
ACCGGCATCGCCGGCACGCTGGCCATACGCTTCATCACCCGGCCGCTGGGCGATGTGGTGGGCCAGGCCGAGGCCATTGC
CGAGCGCCGCTTCCTGCGCATCGCAGAACCCCGCACGCCCGAACTGCGCAGCGTGGTGCGCGCCATGAACAGCATGGTGG
AGCGCCTCAAAGCCCTGTTCAGCGAGGAGGCCGCCCGCCTCGAAGCACTGCGCCAGAAGGTCAACCTCGACGCGCTAACC
GGGCTGTCCGGGCGCGAGCATTTCCTGTCGCAGCTGCGCGAGTTGCTGGTGGGCGAGGACTCTGGCGCCGAGGGCGTGCT
GGTCATGCTGCGCGTAAACGACCTGAACATGCTGAATGCCCGTCTTGGCCACCAGCGTGCAGATACGCTGCTGCAGCAAC
TCGGTGGCGTGCTCAAGGACAGCATGCGGGAGCACAGCGGCCAGCAGGCGGGGAGGCTCAAGGGCGGTGATTTTGCCCTG
GCCTGCCCGGGCATCACCTCCCCGGCACAAGCGGCCAGCGAGCTGCACCAGCGCCTGAACCAGGCCTGGCTGCCCAACTG
GGTGGCCGAAGTGCCTGACCTGTTCCATCTGGCGGCCGTACCCTATCAGCGCGCAGAAAGCATAGGCGATCTGCTGAGCC
GCGCCGACGAGGCCCTGGCCCGTGCCGAGGCCGAGGGGCCGAACAGCTGGCATGCCAGCGAAGCGGACAGCGGCAGCACC
GCACGCCCCGCCGAGCAGTGGCGCAGCCTGCTCACCGAAGCCGTCGCCAGCGGCAAGCTAAGGCTCGCCTTCTACCGCGT
GGTCGGCAGCGGCAGCCAGAACGCCATTCACCAGGAAGGCGTGATCCGCCTGCAAATCGACGACACAGGCACCCTGCTGC
CCGCCCGTGACTTCATGCCGATGGCCGCGCACCTCAACCTCAGCGCGCCGATAGACCTCGAGGTGGTCAGGCTCGCCATA
GCCCATCTGCGCACCACGCCCGGCGACATCGCGGTCAACCTGTCGGCCGAAACCATCGCCGACTTCAGCTTCCGCTATGA
GCTCAGGATGCTGCTGGAATTCCACCCCGAGATCTGCAAGCGTCTGCTGTTCGAGGTACCCGAGCAAGGCGTCTTCAAAC
AGTTCAATGCCTTCCGCGACCTGGTGCTCACCCTCAAGCCACTGGGCTGTCGCGTCGGCATCGAATACTTCGGCCAGCGC
TTTGCCGAGGGTGACAAACTCGCCGACCTGGGCCTGGACTACATCAAGGTCCACCCCAGCTATGTGCGCGACATTGCCCA
CAACCCGGGTAACCAGGAATTCCTCAAGGGCCTGTGCAAGGTGGCACGCAATTTCGGCATCGTGGTGATAGCGCTCGGCG
TCGAGTCCGACAGCGACCTGCCGCTGCTGGCCTCGCTCGGATTTGACGGGGTGACAGGGCCGGGTGTAAAGTGA

Upstream 100 bases:

>100_bases
CGCCAGGAAGGCCTGTCGCCATGATCTCCTCACCCCCTGATCCGTTCCTGCCCTGACCATTTACGCCCTGATTCATTCCC
TCACTCAGCGAGTTACCACC

Downstream 100 bases:

>100_bases
GTCAGTTGTGCTGAAGGCGGTGGCCGGTTCATTCATGCCACGCCCTATCGATCGGAATTGCCGTGAACTGCATGAAGTCC
GTGCCTGCCGGATGGCCCCT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSLIKQLWIAIIVVMTIAFGGSMVVSVLSARHYLEQQLQVKNIDNATALALSLSQLPKDPVTVELQVATQFDAGHYRFIR
IVSPTGQTVVERVFTGQLQGAPAWFARLIPIRAVPGQALIQDGWKQYGTLTLASHEQYVYKSLWDGTLELLLWFVLGSVI
TGIAGTLAIRFITRPLGDVVGQAEAIAERRFLRIAEPRTPELRSVVRAMNSMVERLKALFSEEAARLEALRQKVNLDALT
GLSGREHFLSQLRELLVGEDSGAEGVLVMLRVNDLNMLNARLGHQRADTLLQQLGGVLKDSMREHSGQQAGRLKGGDFAL
ACPGITSPAQAASELHQRLNQAWLPNWVAEVPDLFHLAAVPYQRAESIGDLLSRADEALARAEAEGPNSWHASEADSGST
ARPAEQWRSLLTEAVASGKLRLAFYRVVGSGSQNAIHQEGVIRLQIDDTGTLLPARDFMPMAAHLNLSAPIDLEVVRLAI
AHLRTTPGDIAVNLSAETIADFSFRYELRMLLEFHPEICKRLLFEVPEQGVFKQFNAFRDLVLTLKPLGCRVGIEYFGQR
FAEGDKLADLGLDYIKVHPSYVRDIAHNPGNQEFLKGLCKVARNFGIVVIALGVESDSDLPLLASLGFDGVTGPGVK

Sequences:

>Translated_637_residues
MSLIKQLWIAIIVVMTIAFGGSMVVSVLSARHYLEQQLQVKNIDNATALALSLSQLPKDPVTVELQVATQFDAGHYRFIR
IVSPTGQTVVERVFTGQLQGAPAWFARLIPIRAVPGQALIQDGWKQYGTLTLASHEQYVYKSLWDGTLELLLWFVLGSVI
TGIAGTLAIRFITRPLGDVVGQAEAIAERRFLRIAEPRTPELRSVVRAMNSMVERLKALFSEEAARLEALRQKVNLDALT
GLSGREHFLSQLRELLVGEDSGAEGVLVMLRVNDLNMLNARLGHQRADTLLQQLGGVLKDSMREHSGQQAGRLKGGDFAL
ACPGITSPAQAASELHQRLNQAWLPNWVAEVPDLFHLAAVPYQRAESIGDLLSRADEALARAEAEGPNSWHASEADSGST
ARPAEQWRSLLTEAVASGKLRLAFYRVVGSGSQNAIHQEGVIRLQIDDTGTLLPARDFMPMAAHLNLSAPIDLEVVRLAI
AHLRTTPGDIAVNLSAETIADFSFRYELRMLLEFHPEICKRLLFEVPEQGVFKQFNAFRDLVLTLKPLGCRVGIEYFGQR
FAEGDKLADLGLDYIKVHPSYVRDIAHNPGNQEFLKGLCKVARNFGIVVIALGVESDSDLPLLASLGFDGVTGPGVK
>Mature_636_residues
SLIKQLWIAIIVVMTIAFGGSMVVSVLSARHYLEQQLQVKNIDNATALALSLSQLPKDPVTVELQVATQFDAGHYRFIRI
VSPTGQTVVERVFTGQLQGAPAWFARLIPIRAVPGQALIQDGWKQYGTLTLASHEQYVYKSLWDGTLELLLWFVLGSVIT
GIAGTLAIRFITRPLGDVVGQAEAIAERRFLRIAEPRTPELRSVVRAMNSMVERLKALFSEEAARLEALRQKVNLDALTG
LSGREHFLSQLRELLVGEDSGAEGVLVMLRVNDLNMLNARLGHQRADTLLQQLGGVLKDSMREHSGQQAGRLKGGDFALA
CPGITSPAQAASELHQRLNQAWLPNWVAEVPDLFHLAAVPYQRAESIGDLLSRADEALARAEAEGPNSWHASEADSGSTA
RPAEQWRSLLTEAVASGKLRLAFYRVVGSGSQNAIHQEGVIRLQIDDTGTLLPARDFMPMAAHLNLSAPIDLEVVRLAIA
HLRTTPGDIAVNLSAETIADFSFRYELRMLLEFHPEICKRLLFEVPEQGVFKQFNAFRDLVLTLKPLGCRVGIEYFGQRF
AEGDKLADLGLDYIKVHPSYVRDIAHNPGNQEFLKGLCKVARNFGIVVIALGVESDSDLPLLASLGFDGVTGPGVK

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=420, Percent_Identity=26.1904761904762, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1788849, Length=209, Percent_Identity=24.8803827751196, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=24.6478873239437, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87082096, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081921, Length=453, Percent_Identity=19.6467991169978, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 69902; Mature: 69771

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50885 HAMP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIKQLWIAIIVVMTIAFGGSMVVSVLSARHYLEQQLQVKNIDNATALALSLSQLPKDP
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
VTVELQVATQFDAGHYRFIRIVSPTGQTVVERVFTGQLQGAPAWFARLIPIRAVPGQALI
CEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
QDGWKQYGTLTLASHEQYVYKSLWDGTLELLLWFVLGSVITGIAGTLAIRFITRPLGDVV
HHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQAEAIAERRFLRIAEPRTPELRSVVRAMNSMVERLKALFSEEAARLEALRQKVNLDALT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GLSGREHFLSQLRELLVGEDSGAEGVLVMLRVNDLNMLNARLGHQRADTLLQQLGGVLKD
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHCHHHHHHHHHHHHHHHHH
SMREHSGQQAGRLKGGDFALACPGITSPAQAASELHQRLNQAWLPNWVAEVPDLFHLAAV
HHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
PYQRAESIGDLLSRADEALARAEAEGPNSWHASEADSGSTARPAEQWRSLLTEAVASGKL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCE
RLAFYRVVGSGSQNAIHQEGVIRLQIDDTGTLLPARDFMPMAAHLNLSAPIDLEVVRLAI
EEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHCCCHHHCCCCCCCCHHHHHHHHH
AHLRTTPGDIAVNLSAETIADFSFRYELRMLLEFHPEICKRLLFEVPEQGVFKQFNAFRD
HHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHH
LVLTLKPLGCRVGIEYFGQRFAEGDKLADLGLDYIKVHPSYVRDIAHNPGNQEFLKGLCK
HHHHHCCCCCEECHHHHHHHHCCCCHHHHCCCHHEEECHHHHHHHHCCCCCHHHHHHHHH
VARNFGIVVIALGVESDSDLPLLASLGFDGVTGPGVK
HHHCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLIKQLWIAIIVVMTIAFGGSMVVSVLSARHYLEQQLQVKNIDNATALALSLSQLPKDP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
VTVELQVATQFDAGHYRFIRIVSPTGQTVVERVFTGQLQGAPAWFARLIPIRAVPGQALI
CEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
QDGWKQYGTLTLASHEQYVYKSLWDGTLELLLWFVLGSVITGIAGTLAIRFITRPLGDVV
HHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQAEAIAERRFLRIAEPRTPELRSVVRAMNSMVERLKALFSEEAARLEALRQKVNLDALT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GLSGREHFLSQLRELLVGEDSGAEGVLVMLRVNDLNMLNARLGHQRADTLLQQLGGVLKD
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHCHHHHHHHHHHHHHHHHH
SMREHSGQQAGRLKGGDFALACPGITSPAQAASELHQRLNQAWLPNWVAEVPDLFHLAAV
HHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
PYQRAESIGDLLSRADEALARAEAEGPNSWHASEADSGSTARPAEQWRSLLTEAVASGKL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCE
RLAFYRVVGSGSQNAIHQEGVIRLQIDDTGTLLPARDFMPMAAHLNLSAPIDLEVVRLAI
EEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHCCCHHHCCCCCCCCHHHHHHHHH
AHLRTTPGDIAVNLSAETIADFSFRYELRMLLEFHPEICKRLLFEVPEQGVFKQFNAFRD
HHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHH
LVLTLKPLGCRVGIEYFGQRFAEGDKLADLGLDYIKVHPSYVRDIAHNPGNQEFLKGLCK
HHHHHCCCCCEECHHHHHHHHCCCCHHHHCCCHHEEECHHHHHHHHCCCCCHHHHHHHHH
VARNFGIVVIALGVESDSDLPLLASLGFDGVTGPGVK
HHHCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]