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The map label for this gene is creB [H]

Identifier: 91786148

GI number: 91786148

Start: 260435

End: 261115

Strand: Reverse

Name: creB [H]

Synonym: Bpro_0237

Alternate gene names: 91786148

Gene position: 261115-260435 (Counterclockwise)

Preceding gene: 91786149

Following gene: 91786147

Centisome position: 5.02

GC content: 68.87

Gene sequence:

>681_bases
ATGACCGGCGCGCGCGTTCTGCTGGTTGAGGATGACCCGGCCATCGCCCGGTCCATCGTCTTTGCGCTCGAACGCGATGG
CATCAACCTCACGCACAGCCTGCTGCTCAGCGATGCGCGCCGGCAACTGCTGGTGCGCACGCCCGACGTGGTGATCCTGG
ACATCGGCCTGCCCGACGGCAGCGGCCTTGATTTGTGCAAGGAGCTGCGCGCAGCCGGCAGCATGCCAGTGCTGATTCTC
AGCGCGCACGGCGAGGAAATCGACCGGGTACTCGGGCTGGAGCTGGGCGCCGACGACTACCTGAGCAAACCCTTCAGCCC
GCGCGAGCTGCTGGCGCGCGTGCGCAGCCTGCTCAGGCGCGCGCGCATGCCGCCCGCAGCGCCGGTGCCTGCCAATGGCC
CCTTCGAGATCGACGCAGCGGGCCAGCGCATGCGCCTGCATGGCCGTCCGCTCAACCTGACACGCCGGGAGTTCGGCCTG
CTCGCCGACCTGCTGCACCATCGCGGCCGCATACGCTCACGCGACGAATTGCTGGGCGCAGTCTGGGGTGCCGACTCGGA
CAGCACCGACCGCACGGTGGACACCCACATCAAGACCCTGCGCGCCAAGCTGCAGGAGGCCGCGCCGGAGCGCGACTACA
TCGTGACGCACCGCGGCATGGGCTACTGCCTGGAGATATGA

Upstream 100 bases:

>100_bases
AAACCTTGGGGCCCACACTTTTCACTTCAAGCCTTCGGCGCGCTGCCCCTTGCATGACGCATGGGGCTCATGTTGCGTGG
GCGGCTCTGCGGTGCTGCGG

Downstream 100 bases:

>100_bases
ACACCCCCGTGGCTGCGCTTCGCTTCGCCTCCCCCCTTGCAGGGGGCGACGCCTGTGGTCTGGCAAAGCCAGTCCCACGG
CGCCTGCTGGCAAAAGCCTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTGARVLLVEDDPAIARSIVFALERDGINLTHSLLLSDARRQLLVRTPDVVILDIGLPDGSGLDLCKELRAAGSMPVLIL
SAHGEEIDRVLGLELGADDYLSKPFSPRELLARVRSLLRRARMPPAAPVPANGPFEIDAAGQRMRLHGRPLNLTRREFGL
LADLLHHRGRIRSRDELLGAVWGADSDSTDRTVDTHIKTLRAKLQEAAPERDYIVTHRGMGYCLEI

Sequences:

>Translated_226_residues
MTGARVLLVEDDPAIARSIVFALERDGINLTHSLLLSDARRQLLVRTPDVVILDIGLPDGSGLDLCKELRAAGSMPVLIL
SAHGEEIDRVLGLELGADDYLSKPFSPRELLARVRSLLRRARMPPAAPVPANGPFEIDAAGQRMRLHGRPLNLTRREFGL
LADLLHHRGRIRSRDELLGAVWGADSDSTDRTVDTHIKTLRAKLQEAAPERDYIVTHRGMGYCLEI
>Mature_225_residues
TGARVLLVEDDPAIARSIVFALERDGINLTHSLLLSDARRQLLVRTPDVVILDIGLPDGSGLDLCKELRAAGSMPVLILS
AHGEEIDRVLGLELGADDYLSKPFSPRELLARVRSLLRRARMPPAAPVPANGPFEIDAAGQRMRLHGRPLNLTRREFGLL
ADLLHHRGRIRSRDELLGAVWGADSDSTDRTVDTHIKTLRAKLQEAAPERDYIVTHRGMGYCLEI

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=49.1304347826087, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=39.3665158371041, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=40, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=218, Percent_Identity=37.6146788990826, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.6828193832599, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=38.8646288209607, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=237, Percent_Identity=37.1308016877637, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=36.8421052631579, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.390134529148, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=36.6515837104072, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=30.8695652173913, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.0316742081448, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.858407079646, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=30.7359307359307, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24955; Mature: 24824

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGARVLLVEDDPAIARSIVFALERDGINLTHSLLLSDARRQLLVRTPDVVILDIGLPDG
CCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCEEEEEECCCCC
SGLDLCKELRAAGSMPVLILSAHGEEIDRVLGLELGADDYLSKPFSPRELLARVRSLLRR
CCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHH
ARMPPAAPVPANGPFEIDAAGQRMRLHGRPLNLTRREFGLLADLLHHRGRIRSRDELLGA
HCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
VWGADSDSTDRTVDTHIKTLRAKLQEAAPERDYIVTHRGMGYCLEI
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEC
>Mature Secondary Structure 
TGARVLLVEDDPAIARSIVFALERDGINLTHSLLLSDARRQLLVRTPDVVILDIGLPDG
CCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCEEEEEECCCCC
SGLDLCKELRAAGSMPVLILSAHGEEIDRVLGLELGADDYLSKPFSPRELLARVRSLLRR
CCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHH
ARMPPAAPVPANGPFEIDAAGQRMRLHGRPLNLTRREFGLLADLLHHRGRIRSRDELLGA
HCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
VWGADSDSTDRTVDTHIKTLRAKLQEAAPERDYIVTHRGMGYCLEI
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]