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The map label for this gene is 91786108

Identifier: 91786108

GI number: 91786108

Start: 215033

End: 216007

Strand: Reverse

Name: 91786108

Synonym: Bpro_0197

Alternate gene names: NA

Gene position: 216007-215033 (Counterclockwise)

Preceding gene: 91786109

Following gene: 91786107

Centisome position: 4.15

GC content: 67.38

Gene sequence:

>975_bases
ATGAAAGTCTGCATTTACGGCGCGGGCGCCATTGGTGGCTGGATTGGCAGCGGGCTGGCGCGCGCGGGCTGCAGCGTGAG
CGTGGTGGCCCGTGGCGCCACGCTGGACGCCCTGCAACTGCACGGCCTGCGCCTGCACCAGGGCGGGCGTGTGAGCTCGC
AGGCCGTGGCCTCCAGCGCCTTGCCGGCCGACCTGGGCGTGCAGGACCTGGTGGTGCTGGCCGTCAAGGCACCGTCACTG
CCGGAGGTGGTGCGCCAGATTGCGCCGCTGATCGGGCCCCAGACCACCGTTCTGACCGCCATGAACGGCGTGCCGTGGTG
GTTCTTGCAGGGCTTCGGCGGTGCCTTGGCGGACACGCGCCTGACCTCCATCGACCCGGAAGGTGCGCTAGCCGAAGGCA
TTCCCGCACAGCATATCGTGGGCTGCGTGGTGCATGCCAGCTGCTCGCTGGACGAACCGGGTCAGGTGCACCATCACTTC
GGCAACAAGCTCATTCTGGGCGAGCCCTCGGGTGAAAAGACCGCCCGGGTGCGGCAGCTGGCCGCCCTGCTGGAAAAGGC
CGGCTTCGAAGCCCCCGTGTCCGACCAGATCCAGAAAGACATCTGGTTCAAGCTGTGGGGCAACATGACGGTCAACCCGA
TCAGCGCGCTGACCGGCGCCACCACCGACCGCATCATGGACGACGACCTGGTGCGCGGCTTCATCTCCAGCGTGATGCTG
GAGGCCAAAGAGATAGGCGCGCGCATTGGCATACCCATAGACCAGCGCCCGGAAGACCGCCATGCCGTGACGCTCAAGCT
GGGCGCCTTCAAGACCTCCATGCTGCAGGACGTGGAAGCCGGCAAGGCGGTTGAGCTGGATGCGCTGGTCAGCGCGGTCA
GGGAGCTGGGCATGCTGACGAAGGTGCCCACGCCCTTCACGGACGCGCTGCTGGGCCTGGCGCGGCTGCATGCCCGGGTG
CACGGGCTTTATTGA

Upstream 100 bases:

>100_bases
CGACGCTCCGTCACGCTATCGCTATCAAATAAGGAGCGAAGAGTGGCGATATTGATTGGGCTGCCGGCCCATTTTTATTA
ACAACTTGACAGGGCACAGC

Downstream 100 bases:

>100_bases
TGTCTGGCCCGGCCCGCCGAGCCATCAGCGGCACGGCCTTTGCCACGCTGCTGCTGATCGCGCTGATGATGGGCGCCAAC
CATGTGGCGGCGCGGATTGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKVCIYGAGAIGGWIGSGLARAGCSVSVVARGATLDALQLHGLRLHQGGRVSSQAVASSALPADLGVQDLVVLAVKAPSL
PEVVRQIAPLIGPQTTVLTAMNGVPWWFLQGFGGALADTRLTSIDPEGALAEGIPAQHIVGCVVHASCSLDEPGQVHHHF
GNKLILGEPSGEKTARVRQLAALLEKAGFEAPVSDQIQKDIWFKLWGNMTVNPISALTGATTDRIMDDDLVRGFISSVML
EAKEIGARIGIPIDQRPEDRHAVTLKLGAFKTSMLQDVEAGKAVELDALVSAVRELGMLTKVPTPFTDALLGLARLHARV
HGLY

Sequences:

>Translated_324_residues
MKVCIYGAGAIGGWIGSGLARAGCSVSVVARGATLDALQLHGLRLHQGGRVSSQAVASSALPADLGVQDLVVLAVKAPSL
PEVVRQIAPLIGPQTTVLTAMNGVPWWFLQGFGGALADTRLTSIDPEGALAEGIPAQHIVGCVVHASCSLDEPGQVHHHF
GNKLILGEPSGEKTARVRQLAALLEKAGFEAPVSDQIQKDIWFKLWGNMTVNPISALTGATTDRIMDDDLVRGFISSVML
EAKEIGARIGIPIDQRPEDRHAVTLKLGAFKTSMLQDVEAGKAVELDALVSAVRELGMLTKVPTPFTDALLGLARLHARV
HGLY
>Mature_324_residues
MKVCIYGAGAIGGWIGSGLARAGCSVSVVARGATLDALQLHGLRLHQGGRVSSQAVASSALPADLGVQDLVVLAVKAPSL
PEVVRQIAPLIGPQTTVLTAMNGVPWWFLQGFGGALADTRLTSIDPEGALAEGIPAQHIVGCVVHASCSLDEPGQVHHHF
GNKLILGEPSGEKTARVRQLAALLEKAGFEAPVSDQIQKDIWFKLWGNMTVNPISALTGATTDRIMDDDLVRGFISSVML
EAKEIGARIGIPIDQRPEDRHAVTLKLGAFKTSMLQDVEAGKAVELDALVSAVRELGMLTKVPTPFTDALLGLARLHARV
HGLY

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34139; Mature: 34139

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCIYGAGAIGGWIGSGLARAGCSVSVVARGATLDALQLHGLRLHQGGRVSSQAVASSA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCEEHHHHHCCEEECCCCCCHHHHHHHHC
LPADLGVQDLVVLAVKAPSLPEVVRQIAPLIGPQTTVLTAMNGVPWWFLQGFGGALADTR
CCCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHCCCCHHHCCC
LTSIDPEGALAEGIPAQHIVGCVVHASCSLDEPGQVHHHFGNKLILGEPSGEKTARVRQL
CCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHH
AALLEKAGFEAPVSDQIQKDIWFKLWGNMTVNPISALTGATTDRIMDDDLVRGFISSVML
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EAKEIGARIGIPIDQRPEDRHAVTLKLGAFKTSMLQDVEAGKAVELDALVSAVRELGMLT
HHHHHCCEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
KVPTPFTDALLGLARLHARVHGLY
CCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVCIYGAGAIGGWIGSGLARAGCSVSVVARGATLDALQLHGLRLHQGGRVSSQAVASSA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCEEHHHHHCCEEECCCCCCHHHHHHHHC
LPADLGVQDLVVLAVKAPSLPEVVRQIAPLIGPQTTVLTAMNGVPWWFLQGFGGALADTR
CCCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHCCCCHHHCCC
LTSIDPEGALAEGIPAQHIVGCVVHASCSLDEPGQVHHHFGNKLILGEPSGEKTARVRQL
CCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHH
AALLEKAGFEAPVSDQIQKDIWFKLWGNMTVNPISALTGATTDRIMDDDLVRGFISSVML
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EAKEIGARIGIPIDQRPEDRHAVTLKLGAFKTSMLQDVEAGKAVELDALVSAVRELGMLT
HHHHHCCEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
KVPTPFTDALLGLARLHARVHGLY
CCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]