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The map label for this gene is qseD [H]

Identifier: 91786034

GI number: 91786034

Start: 125452

End: 126354

Strand: Direct

Name: qseD [H]

Synonym: Bpro_0123

Alternate gene names: 91786034

Gene position: 125452-126354 (Clockwise)

Preceding gene: 91786032

Following gene: 91786035

Centisome position: 2.41

GC content: 69.77

Gene sequence:

>903_bases
GTGGACCATAAATGGCTGGAAGATTTCATTGTGCTGGCGCGAGAGCGCAGCTTTTCAAGGGCAGCCGAACTGCGTCATGT
GACGCAGCCGCAGTTCTCGCGCCGCATACGCGCACTGGAGCTGTGGGCCGGCGCCGACCTGATCAACCGCGCCAGCATGC
CGCTGGGGCTGACTGCCGCTGGCGAGGAACTGCTGCCGGTGGCGCACCGGGCGGCGGCGAGCCTCAACGACGCCCGCGCC
CGCATACGCCATGCGCGTGGCAGCCTTGACTGGGTCACGCTGGCGACCGGGCGCACGCTGTCACGCACGGCCGTGCCGGA
CTGGCTCGCGCGCGTCAAGCGTTCGGCCGGCGAGTTTCGGCTGCGCATCCTGACAGGCTCCATCCATGAGGGGGCCACGG
CCCTGGAGCAGGGCGCCGCCGATTTCCTGTTGTCGTTTACCCATCCGCGCCTGCCGCTGCTGCTGGACGAGCAGACGTTT
GAAGGCATCACGCTGGGCACCGACGAGCTGGTGGCCGTGAGCGCGCCGCGCGGCGATGGCCAGCCGCGGCATGCCTTGCC
TGGCACGGACCGCCACCCGGTGCCGGTGCTGGGCTATGCCCCGACGCTGGCGCTCAGCCAGATCCTTCAGGACGGACTCA
GCCGCAGTTCGCGCGAGCTGCACCTGCACACGGTGACCGAATCGGACTTTGCCGAGTCGCTGCATGAGCAGGCGCTTCAG
GGCGTGGGCATGGCGTGGCTGCCCCGCGGGTTGGTGGATGGCGACCTGCGCAGCGGCCGGCTGGTGGAGGCGGACGGCAA
AGGTGCGGCGGTCCGCTTTGAAATCCGCCTGTACCGCCCGCGGAGCCCGCGCAACGATCTGGTGCAGCGCATCTGGTCGG
CCAGTACCGCAGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
TTGCGTGCGGTCATGCCTTGATGGTAGCCGGGGCTCCCCGCGGCCCGGCGGTGGGTGACAAGGAATACCATCACATGAAC
TGACAGGACAGGGTGTTGCT

Downstream 100 bases:

>100_bases
GTCCGGGGCTCGCATGCTCCCATGCGTGATGCGCATGCGCGGCGCGCGGACGACTTCTAGACTGGCGCCATCAACAAGGA
GCCCGTCATGCCTGAAACGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDHKWLEDFIVLARERSFSRAAELRHVTQPQFSRRIRALELWAGADLINRASMPLGLTAAGEELLPVAHRAAASLNDARA
RIRHARGSLDWVTLATGRTLSRTAVPDWLARVKRSAGEFRLRILTGSIHEGATALEQGAADFLLSFTHPRLPLLLDEQTF
EGITLGTDELVAVSAPRGDGQPRHALPGTDRHPVPVLGYAPTLALSQILQDGLSRSSRELHLHTVTESDFAESLHEQALQ
GVGMAWLPRGLVDGDLRSGRLVEADGKGAAVRFEIRLYRPRSPRNDLVQRIWSASTAAGA

Sequences:

>Translated_300_residues
MDHKWLEDFIVLARERSFSRAAELRHVTQPQFSRRIRALELWAGADLINRASMPLGLTAAGEELLPVAHRAAASLNDARA
RIRHARGSLDWVTLATGRTLSRTAVPDWLARVKRSAGEFRLRILTGSIHEGATALEQGAADFLLSFTHPRLPLLLDEQTF
EGITLGTDELVAVSAPRGDGQPRHALPGTDRHPVPVLGYAPTLALSQILQDGLSRSSRELHLHTVTESDFAESLHEQALQ
GVGMAWLPRGLVDGDLRSGRLVEADGKGAAVRFEIRLYRPRSPRNDLVQRIWSASTAAGA
>Mature_300_residues
MDHKWLEDFIVLARERSFSRAAELRHVTQPQFSRRIRALELWAGADLINRASMPLGLTAAGEELLPVAHRAAASLNDARA
RIRHARGSLDWVTLATGRTLSRTAVPDWLARVKRSAGEFRLRILTGSIHEGATALEQGAADFLLSFTHPRLPLLLDEQTF
EGITLGTDELVAVSAPRGDGQPRHALPGTDRHPVPVLGYAPTLALSQILQDGLSRSSRELHLHTVTESDFAESLHEQALQ
GVGMAWLPRGLVDGDLRSGRLVEADGKGAAVRFEIRLYRPRSPRNDLVQRIWSASTAAGA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=297, Percent_Identity=30.3030303030303, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787601, Length=257, Percent_Identity=26.8482490272374, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994962, Length=140, Percent_Identity=32.1428571428571, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32904; Mature: 32904

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHKWLEDFIVLARERSFSRAAELRHVTQPQFSRRIRALELWAGADLINRASMPLGLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCEECC
GEELLPVAHRAAASLNDARARIRHARGSLDWVTLATGRTLSRTAVPDWLARVKRSAGEFR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHHHCCCCEE
LRILTGSIHEGATALEQGAADFLLSFTHPRLPLLLDEQTFEGITLGTDELVAVSAPRGDG
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEECCCCEEEEECCCCCC
QPRHALPGTDRHPVPVLGYAPTLALSQILQDGLSRSSRELHLHTVTESDFAESLHEQALQ
CCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHH
GVGMAWLPRGLVDGDLRSGRLVEADGKGAAVRFEIRLYRPRSPRNDLVQRIWSASTAAGA
CCCHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDHKWLEDFIVLARERSFSRAAELRHVTQPQFSRRIRALELWAGADLINRASMPLGLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCEECC
GEELLPVAHRAAASLNDARARIRHARGSLDWVTLATGRTLSRTAVPDWLARVKRSAGEFR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHHHCCCCEE
LRILTGSIHEGATALEQGAADFLLSFTHPRLPLLLDEQTFEGITLGTDELVAVSAPRGDG
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEECCCCEEEEECCCCCC
QPRHALPGTDRHPVPVLGYAPTLALSQILQDGLSRSSRELHLHTVTESDFAESLHEQALQ
CCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHH
GVGMAWLPRGLVDGDLRSGRLVEADGKGAAVRFEIRLYRPRSPRNDLVQRIWSASTAAGA
CCCHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]