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The map label for this gene is glcD [H]

Identifier: 91786022

GI number: 91786022

Start: 113164

End: 114585

Strand: Reverse

Name: glcD [H]

Synonym: Bpro_0111

Alternate gene names: 91786022

Gene position: 114585-113164 (Counterclockwise)

Preceding gene: 91786023

Following gene: 91786021

Centisome position: 2.2

GC content: 65.26

Gene sequence:

>1422_bases
ATGAATGCACCCCTACCCGTCCATTTGCTGCCGGAAATTCATCAGCGCGAGACACCTGCCGCGCTGCTGGACGCACTCAA
GGCCCGCTTCGCCGAGCGTTGCTCCACCGCGCTGGTGGTGCGCGAGCAGCACGGTCGTGACGAGTCCTCGTTCGCCGCGC
CGCCACCCGCCGCCGTGGTCTTTGCCGAAAGCACGCTGGACGTGGCCGACGCCGTGAAGCTGGCCAGCCAGTACAACGTG
CCGGTCATCCCCTTTGGCGTTGGCACCTCGCTGGAGGGCCATCTGCTGGCCGTGCAGGGCGGCATCAGCATTGATGTGAG
CCGCATGAACAAGGTGCTGTCGATCAACGCGGAAGACCTGACCGTGACGGTGCAGCCCGGCGTGACGCGCAAGCAGCTCA
ATGAAGAAGTGAAAAGCACGGGCCTGTTCTTCCCCATCGACCCCGGCGCCGATGCGACGCTGGGCGGCATGAGCGCGACG
CGCGCCAGCGGCACCAACGCCGTGCGCTACGGCACCATGCGCGAAAACGTGCTCGCGCTGGAAGTGGTGACGGCCAGCGG
CGAGGTCATCCGCACCGGCACCCGCGCCAAGAAATCATCGGCCGGCTACGACCTGACGCGCCTGATGGTGGGCAGCGAAG
GCACGCTGGGTGTCATCACCGAAGTCACGGTCAGACTCTATCCGCTGCCGGAAGCCATTTCAGCGGCGATCTGCTCCTTC
CCCAGCATCGAGGCGGCCGTGCGCACCACGATTGAAGTGATCCAGATGGGCGTGCCGATTGCGCGCGTGGAGCTCATCGA
CCACAACACCGTCCGCATGGTCAACGCCTATGCCAAGCTGGGCCTGCGCGAAGAACCCATGCTGCTGATGGAGTTCCATG
GCTCACCCAGCAGCGTGAAGGAGCAGGCCGAGCTGGTGCAGGAGCTCGCCAGCGGCCATGGCGGCCAGGCGTTTGAATGG
GCCAGCACGCCGGAAGAGCGCACCCGGCTCTGGACGGCGCGCCACAACGCCTATTTCGCCGCCATCCAGTCGCGCCCCGG
CTGCCGCGCCATCTCCACCGACACCTGCGTGCCGATTTCGCGCCTGGCCGACTGCCTGCTGGAGTCGGTCGCCGAAGTCG
ACGCCAGCGGCATTCCCTACTTCCTCGTCGGCCACGTGGGCGACGGCAATTTCCACTTTGGCTATTTGATCGACCCCGAG
CAGCCCAAAGAGCGTGAAGTGGCCGAAGAACTGAACCACAAGCTGGTCAGCCGCGCGCTGGCGCTGGAAGGCACCTGCAC
CGGCGAGCACGGCGTGGGCCTGCACAAAATGGATTTCCTGGTGACGGAAACCGGTGATGCCGCCGTCGAGATGATGCGCA
CCATCAAGCGCGCGCTGGACCCGAAAAACATCATGAACCCGGGCAAGATTTTCACGCTGTGA

Upstream 100 bases:

>100_bases
AGGTGCTCCGGCAACGCCCCGGCGTCCGGGAACTCCACAAGCTTTCTTTGGCAGACGCGACGCGCACGTCGTAAACTGTG
CCATTGACCTGGAGACACCC

Downstream 100 bases:

>100_bases
GTACAGGGGCTGCTGGTCGATTTCTGCTGGCCTGAAGTGCCATGAAAGTGCCATGAGATTGCCCCGCACGCCTTGCCTGC
AAACAAATCCTGGTGACCTG

Product: FAD linked oxidase-like protein

Products: pyruvate; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNAPLPVHLLPEIHQRETPAALLDALKARFAERCSTALVVREQHGRDESSFAAPPPAAVVFAESTLDVADAVKLASQYNV
PVIPFGVGTSLEGHLLAVQGGISIDVSRMNKVLSINAEDLTVTVQPGVTRKQLNEEVKSTGLFFPIDPGADATLGGMSAT
RASGTNAVRYGTMRENVLALEVVTASGEVIRTGTRAKKSSAGYDLTRLMVGSEGTLGVITEVTVRLYPLPEAISAAICSF
PSIEAAVRTTIEVIQMGVPIARVELIDHNTVRMVNAYAKLGLREEPMLLMEFHGSPSSVKEQAELVQELASGHGGQAFEW
ASTPEERTRLWTARHNAYFAAIQSRPGCRAISTDTCVPISRLADCLLESVAEVDASGIPYFLVGHVGDGNFHFGYLIDPE
QPKEREVAEELNHKLVSRALALEGTCTGEHGVGLHKMDFLVTETGDAAVEMMRTIKRALDPKNIMNPGKIFTL

Sequences:

>Translated_473_residues
MNAPLPVHLLPEIHQRETPAALLDALKARFAERCSTALVVREQHGRDESSFAAPPPAAVVFAESTLDVADAVKLASQYNV
PVIPFGVGTSLEGHLLAVQGGISIDVSRMNKVLSINAEDLTVTVQPGVTRKQLNEEVKSTGLFFPIDPGADATLGGMSAT
RASGTNAVRYGTMRENVLALEVVTASGEVIRTGTRAKKSSAGYDLTRLMVGSEGTLGVITEVTVRLYPLPEAISAAICSF
PSIEAAVRTTIEVIQMGVPIARVELIDHNTVRMVNAYAKLGLREEPMLLMEFHGSPSSVKEQAELVQELASGHGGQAFEW
ASTPEERTRLWTARHNAYFAAIQSRPGCRAISTDTCVPISRLADCLLESVAEVDASGIPYFLVGHVGDGNFHFGYLIDPE
QPKEREVAEELNHKLVSRALALEGTCTGEHGVGLHKMDFLVTETGDAAVEMMRTIKRALDPKNIMNPGKIFTL
>Mature_473_residues
MNAPLPVHLLPEIHQRETPAALLDALKARFAERCSTALVVREQHGRDESSFAAPPPAAVVFAESTLDVADAVKLASQYNV
PVIPFGVGTSLEGHLLAVQGGISIDVSRMNKVLSINAEDLTVTVQPGVTRKQLNEEVKSTGLFFPIDPGADATLGGMSAT
RASGTNAVRYGTMRENVLALEVVTASGEVIRTGTRAKKSSAGYDLTRLMVGSEGTLGVITEVTVRLYPLPEAISAAICSF
PSIEAAVRTTIEVIQMGVPIARVELIDHNTVRMVNAYAKLGLREEPMLLMEFHGSPSSVKEQAELVQELASGHGGQAFEW
ASTPEERTRLWTARHNAYFAAIQSRPGCRAISTDTCVPISRLADCLLESVAEVDASGIPYFLVGHVGDGNFHFGYLIDPE
QPKEREVAEELNHKLVSRALALEGTCTGEHGVGLHKMDFLVTETGDAAVEMMRTIKRALDPKNIMNPGKIFTL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=454, Percent_Identity=50.6607929515419, Blast_Score=478, Evalue=1e-135,
Organism=Homo sapiens, GI37595754, Length=477, Percent_Identity=48.2180293501048, Blast_Score=468, Evalue=1e-132,
Organism=Homo sapiens, GI119964728, Length=413, Percent_Identity=30.0242130750605, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4501993, Length=463, Percent_Identity=26.5658747300216, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789351, Length=422, Percent_Identity=31.7535545023697, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787977, Length=496, Percent_Identity=27.6209677419355, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI48994907, Length=499, Percent_Identity=24.0480961923848, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994914, Length=171, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71992373, Length=436, Percent_Identity=48.394495412844, Blast_Score=433, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71992381, Length=436, Percent_Identity=47.0183486238532, Blast_Score=413, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI71992392, Length=380, Percent_Identity=48.4210526315789, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17556096, Length=455, Percent_Identity=27.032967032967, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17534361, Length=500, Percent_Identity=25.4, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320027, Length=427, Percent_Identity=39.344262295082, Blast_Score=316, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6320764, Length=431, Percent_Identity=25.754060324826, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320023, Length=416, Percent_Identity=27.1634615384615, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24653753, Length=466, Percent_Identity=30.2575107296137, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI18921117, Length=498, Percent_Identity=26.7068273092369, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24639277, Length=498, Percent_Identity=26.7068273092369, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24639275, Length=498, Percent_Identity=26.7068273092369, Blast_Score=151, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.2.4

Molecular weight: Translated: 50887; Mature: 50887

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLPVHLLPEIHQRETPAALLDALKARFAERCSTALVVREQHGRDESSFAAPPPAAVV
CCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCCCCCCCEEE
FAESTLDVADAVKLASQYNVPVIPFGVGTSLEGHLLAVQGGISIDVSRMNKVLSINAEDL
EECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCEEEHHHCCEEEEECCCCE
TVTVQPGVTRKQLNEEVKSTGLFFPIDPGADATLGGMSATRASGTNAVRYGTMRENVLAL
EEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCHHCCEEEE
EVVTASGEVIRTGTRAKKSSAGYDLTRLMVGSEGTLGVITEVTVRLYPLPEAISAAICSF
EEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEECCHHHHHHHHHCC
PSIEAAVRTTIEVIQMGVPIARVELIDHNTVRMVNAYAKLGLREEPMLLMEFHGSPSSVK
CCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
EQAELVQELASGHGGQAFEWASTPEERTRLWTARHNAYFAAIQSRPGCRAISTDTCVPIS
HHHHHHHHHHCCCCCCEEECCCCCHHHHHEEEEECCEEEEEEECCCCCCCCCCCCCCCHH
RLADCLLESVAEVDASGIPYFLVGHVGDGNFHFGYLIDPEQPKEREVAEELNHKLVSRAL
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
ALEGTCTGEHGVGLHKMDFLVTETGDAAVEMMRTIKRALDPKNIMNPGKIFTL
HHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEC
>Mature Secondary Structure
MNAPLPVHLLPEIHQRETPAALLDALKARFAERCSTALVVREQHGRDESSFAAPPPAAVV
CCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCCCCCCCEEE
FAESTLDVADAVKLASQYNVPVIPFGVGTSLEGHLLAVQGGISIDVSRMNKVLSINAEDL
EECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCEEEHHHCCEEEEECCCCE
TVTVQPGVTRKQLNEEVKSTGLFFPIDPGADATLGGMSATRASGTNAVRYGTMRENVLAL
EEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCHHCCEEEE
EVVTASGEVIRTGTRAKKSSAGYDLTRLMVGSEGTLGVITEVTVRLYPLPEAISAAICSF
EEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEECCHHHHHHHHHCC
PSIEAAVRTTIEVIQMGVPIARVELIDHNTVRMVNAYAKLGLREEPMLLMEFHGSPSSVK
CCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
EQAELVQELASGHGGQAFEWASTPEERTRLWTARHNAYFAAIQSRPGCRAISTDTCVPIS
HHHHHHHHHHCCCCCCEEECCCCCHHHHHEEEEECCEEEEEEECCCCCCCCCCCCCCCHH
RLADCLLESVAEVDASGIPYFLVGHVGDGNFHFGYLIDPEQPKEREVAEELNHKLVSRAL
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
ALEGTCTGEHGVGLHKMDFLVTETGDAAVEMMRTIKRALDPKNIMNPGKIFTL
HHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-lactate; ferricytochrome c

Specific reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]