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The map label for this gene is dppA [H]

Identifier: 91785971

GI number: 91785971

Start: 59868

End: 61487

Strand: Direct

Name: dppA [H]

Synonym: Bpro_0058

Alternate gene names: 91785971

Gene position: 59868-61487 (Clockwise)

Preceding gene: 91785970

Following gene: 91785972

Centisome position: 1.15

GC content: 63.33

Gene sequence:

>1620_bases
ATGAATGAAAGCAAGAAACTGCAAGCCTTGATCGGCCCCCAGGAAAGCATGCGCGTGATGAACGCGATGCAGGCAGGCGC
CAAGCGGCGCGATGTGCTCGCCATGCTCATGGCAGGCGGCATGCAGGCCACGCTGGCCGGCAGCCTGGCGGGCATTGCCG
GCGCCGCCCATGCGCAGACGCCGCGCCGTGGCGGACGGATCCGGGTGGCCGGCGCCACCGCTGCAATCAATGACACGCTG
GATCCGGCCAAGCAGTCCAACCAGAGCGACTACATCCGCGGCAGCATGTTCTACAACGGCCTCACGGTGCTGGATGGCAG
CCTCACGCCGCGCCCCGCGCTGGCCGAAGAGTTCACCACCAGGGATGCGACCACCTGGGTCTTCAAGCTGCGCAAGGGCG
TGGTCTTTCATGACGGCAAGCCGCTGGTCCCAGCCGACGTGGTGTTCTCGCTGATGCGCCACAAGGACCCGGCCACTGCC
TCCAAGGCCAAGGCTCTGGCCGACCAGATCGACGACGTGAAGGCCAGCGGCCCTAACGAAGTGACGATCAAGCTCAAGGC
GCCCAACGCCGACTTGCCGGTGATCCTGGGCACCTTCCACTTCCATATCGTCAAGGACGGCACCACCGACTTCAATGCCG
GCATCGGCACCGGCCCTTACAAGGTCAAGGAATTCAAGCCTGGCGTGCGCTCGATCGCGGTGCGCAACGAGGCCTATTGG
AAGCCGGGCCGCCCTTACCTCGATGAGATTGAATATGTGGGCATCGGCGATGAAGGCGCGCGTGTCAATGCGCTGCTGTC
GGGCGACCTGGACCTGGTGGGCTCGGTCAATCCACGTTCGGTGCAGCGTGTGCGCGACTCCGCCGGCCATGCGATCTTTG
AGACGCAGTCGGGCGGGTACACCGACCTGGTGATGCGCCGCGACGGTGGTCCGGGCTCCAACCCCGACTTCGTGATGGCC
ATGAAATACATGTTTGACCGCGAGCAGATGAAGCGTTCCATTGCGCTGGGCCATGCGGTCGTTGCCAACGACCAGCCTAT
CGATCCGACCAACCGCTTTTATTTTGCCGGCCTGCCGCAGCGCGCCTTCGATCTGGACAAGGCCAAGTTCCACTTGCAAA
AAGCCAATCTGGGCAGCGCCCCGATTCCGGTTGTGGCCTCGCCCGCAGCGCTGTATTCTGTCGAGATGGCATTGGTGATG
CAGCAGACGGCGCAGAAACTGGGCTTGAACCTGGACGTCAAACGCATGCCCGCCGATGGCTACTGGTCGAATCACTGGAT
GAAAAGCCCGGTCGGTTTCGGCAACGTCAATCCGCGCCCCAGCGCCGACACGCTGTTCACGCAGTTCTTCAAGTCGGATG
CGGCCTGGAACGAGTCGGGCTGGAAAAGCGAGAAGTTCGACCAGCTGCTGGTTGCCGCGCGCGCCGAAACCGACGACACC
AAGCGCCGCAAGATGTACGCCGACATGCAGGTGCTGGTGCACGAGCAGGGCGGCATCGGCATTCCGCTGTTCCTGGCCAG
CATTGACGGCCACTCGAAGAAACTCAAGGGCTTGTCGCCGATCCCGGTCGGCGGCCTGATGGGCTACGCCTTCGCTGAAC
ACGTCTGGCTGGAAGCATGA

Upstream 100 bases:

>100_bases
GCCCTGGTTTTTGCCCGCGATCGGCCTGTACTACCGCATCAAAGACAAATTGCTCTGATCTTTTTTAGTTGTTATCGACC
CACCACCCAGGAGAACTGCC

Downstream 100 bases:

>100_bases
GCCCCCACGCTCGGCACTGCGTGTCCTCGCTGCCCCCCGAGGGGGCGCTGCGCCTGCGGCCCGGCAAAGCCGGTTCCGCG
GCCCCTGCTGGAAGGGGAGG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MNESKKLQALIGPQESMRVMNAMQAGAKRRDVLAMLMAGGMQATLAGSLAGIAGAAHAQTPRRGGRIRVAGATAAINDTL
DPAKQSNQSDYIRGSMFYNGLTVLDGSLTPRPALAEEFTTRDATTWVFKLRKGVVFHDGKPLVPADVVFSLMRHKDPATA
SKAKALADQIDDVKASGPNEVTIKLKAPNADLPVILGTFHFHIVKDGTTDFNAGIGTGPYKVKEFKPGVRSIAVRNEAYW
KPGRPYLDEIEYVGIGDEGARVNALLSGDLDLVGSVNPRSVQRVRDSAGHAIFETQSGGYTDLVMRRDGGPGSNPDFVMA
MKYMFDREQMKRSIALGHAVVANDQPIDPTNRFYFAGLPQRAFDLDKAKFHLQKANLGSAPIPVVASPAALYSVEMALVM
QQTAQKLGLNLDVKRMPADGYWSNHWMKSPVGFGNVNPRPSADTLFTQFFKSDAAWNESGWKSEKFDQLLVAARAETDDT
KRRKMYADMQVLVHEQGGIGIPLFLASIDGHSKKLKGLSPIPVGGLMGYAFAEHVWLEA

Sequences:

>Translated_539_residues
MNESKKLQALIGPQESMRVMNAMQAGAKRRDVLAMLMAGGMQATLAGSLAGIAGAAHAQTPRRGGRIRVAGATAAINDTL
DPAKQSNQSDYIRGSMFYNGLTVLDGSLTPRPALAEEFTTRDATTWVFKLRKGVVFHDGKPLVPADVVFSLMRHKDPATA
SKAKALADQIDDVKASGPNEVTIKLKAPNADLPVILGTFHFHIVKDGTTDFNAGIGTGPYKVKEFKPGVRSIAVRNEAYW
KPGRPYLDEIEYVGIGDEGARVNALLSGDLDLVGSVNPRSVQRVRDSAGHAIFETQSGGYTDLVMRRDGGPGSNPDFVMA
MKYMFDREQMKRSIALGHAVVANDQPIDPTNRFYFAGLPQRAFDLDKAKFHLQKANLGSAPIPVVASPAALYSVEMALVM
QQTAQKLGLNLDVKRMPADGYWSNHWMKSPVGFGNVNPRPSADTLFTQFFKSDAAWNESGWKSEKFDQLLVAARAETDDT
KRRKMYADMQVLVHEQGGIGIPLFLASIDGHSKKLKGLSPIPVGGLMGYAFAEHVWLEA
>Mature_539_residues
MNESKKLQALIGPQESMRVMNAMQAGAKRRDVLAMLMAGGMQATLAGSLAGIAGAAHAQTPRRGGRIRVAGATAAINDTL
DPAKQSNQSDYIRGSMFYNGLTVLDGSLTPRPALAEEFTTRDATTWVFKLRKGVVFHDGKPLVPADVVFSLMRHKDPATA
SKAKALADQIDDVKASGPNEVTIKLKAPNADLPVILGTFHFHIVKDGTTDFNAGIGTGPYKVKEFKPGVRSIAVRNEAYW
KPGRPYLDEIEYVGIGDEGARVNALLSGDLDLVGSVNPRSVQRVRDSAGHAIFETQSGGYTDLVMRRDGGPGSNPDFVMA
MKYMFDREQMKRSIALGHAVVANDQPIDPTNRFYFAGLPQRAFDLDKAKFHLQKANLGSAPIPVVASPAALYSVEMALVM
QQTAQKLGLNLDVKRMPADGYWSNHWMKSPVGFGNVNPRPSADTLFTQFFKSDAAWNESGWKSEKFDQLLVAARAETDDT
KRRKMYADMQVLVHEQGGIGIPLFLASIDGHSKKLKGLSPIPVGGLMGYAFAEHVWLEA

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=476, Percent_Identity=24.3697478991597, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787052, Length=482, Percent_Identity=24.2738589211618, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787495, Length=276, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787762, Length=489, Percent_Identity=24.5398773006135, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789887, Length=357, Percent_Identity=26.3305322128852, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081878, Length=282, Percent_Identity=24.113475177305, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58559; Mature: 58559

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESKKLQALIGPQESMRVMNAMQAGAKRRDVLAMLMAGGMQATLAGSLAGIAGAAHAQT
CCCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCC
PRRGGRIRVAGATAAINDTLDPAKQSNQSDYIRGSMFYNGLTVLDGSLTPRPALAEEFTT
CCCCCEEEEEECCEEECCCCCHHHHCCCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHC
RDATTWVFKLRKGVVFHDGKPLVPADVVFSLMRHKDPATASKAKALADQIDDVKASGPNE
CCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCE
VTIKLKAPNADLPVILGTFHFHIVKDGTTDFNAGIGTGPYKVKEFKPGVRSIAVRNEAYW
EEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCEEEHHCCCCHHHEEECCCCCC
KPGRPYLDEIEYVGIGDEGARVNALLSGDLDLVGSVNPRSVQRVRDSAGHAIFETQSGGY
CCCCCHHHCEEEEEECCCCCEEEEEEECCCEEEECCCHHHHHHHHHHCCCEEEEECCCCC
TDLVMRRDGGPGSNPDFVMAMKYMFDREQMKRSIALGHAVVANDQPIDPTNRFYFAGLPQ
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEECCCH
RAFDLDKAKFHLQKANLGSAPIPVVASPAALYSVEMALVMQQTAQKLGLNLDVKRMPADG
HHHCCCHHHEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
YWSNHWMKSPVGFGNVNPRPSADTLFTQFFKSDAAWNESGWKSEKFDQLLVAARAETDDT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHH
KRRKMYADMQVLVHEQGGIGIPLFLASIDGHSKKLKGLSPIPVGGLMGYAFAEHVWLEA
HHHHHHHCEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MNESKKLQALIGPQESMRVMNAMQAGAKRRDVLAMLMAGGMQATLAGSLAGIAGAAHAQT
CCCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCC
PRRGGRIRVAGATAAINDTLDPAKQSNQSDYIRGSMFYNGLTVLDGSLTPRPALAEEFTT
CCCCCEEEEEECCEEECCCCCHHHHCCCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHC
RDATTWVFKLRKGVVFHDGKPLVPADVVFSLMRHKDPATASKAKALADQIDDVKASGPNE
CCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCE
VTIKLKAPNADLPVILGTFHFHIVKDGTTDFNAGIGTGPYKVKEFKPGVRSIAVRNEAYW
EEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCEEEHHCCCCHHHEEECCCCCC
KPGRPYLDEIEYVGIGDEGARVNALLSGDLDLVGSVNPRSVQRVRDSAGHAIFETQSGGY
CCCCCHHHCEEEEEECCCCCEEEEEEECCCEEEECCCHHHHHHHHHHCCCEEEEECCCCC
TDLVMRRDGGPGSNPDFVMAMKYMFDREQMKRSIALGHAVVANDQPIDPTNRFYFAGLPQ
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEECCCH
RAFDLDKAKFHLQKANLGSAPIPVVASPAALYSVEMALVMQQTAQKLGLNLDVKRMPADG
HHHCCCHHHEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
YWSNHWMKSPVGFGNVNPRPSADTLFTQFFKSDAAWNESGWKSEKFDQLLVAARAETDDT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHH
KRRKMYADMQVLVHEQGGIGIPLFLASIDGHSKKLKGLSPIPVGGLMGYAFAEHVWLEA
HHHHHHHCEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]