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The map label for this gene is siaP [H]

Identifier: 91785948

GI number: 91785948

Start: 37198

End: 38217

Strand: Reverse

Name: siaP [H]

Synonym: Bpro_0035

Alternate gene names: 91785948

Gene position: 38217-37198 (Counterclockwise)

Preceding gene: 91785952

Following gene: 91785947

Centisome position: 0.73

GC content: 64.41

Gene sequence:

>1020_bases
ATGACCGAAGTCACCCGCCGCAGCGTCCTGCGCACCCTGTCCGCCGTCCCTGCGGCCGGCATTGCCGCAGCCCTGCCCTC
GATGGCGCGCGCCGCCGAGTTTTCCTACAAATACGGCAACAACCTGCCCGTCACCCATCCGCTGAACATCCGCGCCCAGC
AGGCCGCCGACCGCATCCTGAAAGAAACGAACGGCCGGGTCGAGATCAAGATCTTCCCGAACAACCAGCTCGGCGGTGAC
ACCGACATGCTGGCGCAGGTGCGCTCCGGCGGCATCGAGTTCTTCACGCCCTCGGCGCTGGTCATCGCCACGCTGGTGCC
GGTGGCGGCCATCAATGCCGTCGGCTTTGCGTTCTCCGACTACAACCAGGTCTGGGGCGCGATGGACGGCAAGCTGGGCG
CGCATGTGCGTGAGGCCATCAGCAAGTCACGGCTGTATGCGTTTGAAAAAATGTGGGACAACGGTTTCCGCCAGACCACC
AGCAGCAAGGCACCCGTCACCAGCGCGAAAGACATGGACGGCCTGAAGATCCGCGTGCCGGTCAGCCCGCTGTCGATCTC
GATGTTCAAGGGCCTGGGCGCCGCGCCGGCCAGCCTGCAGTTCAGCGAGGTGTATTCCTCGCTGCAGACCAAGATCGTCG
ACGCCCAGGAAAACCCGCTGCCCATCATCCAGGTGGCCAAGCTGTACGAAGTGCAGAAGTTCTGCTCGATGACCAACCAC
ATCTGGGATGGCTACTGGTTCATCGCCAACGGCCGCGCCTGGGAAAAACTGCCCGCCGACCTGAAAACCATCGTGGCGCG
CGCCATCAATGAAGCTGGCCTGCAGCAGCGCGACGACATCAAGAAGCTCAACGAAACCGTCGCCGCCGACCTGCAGTCCA
AGGGCCTAGCCATCAACCGGCCGGCCTCCGACAGCTTCCGGGCCAAGCTGCGCGAAGCCGGGTTTTATGGCGAGTGGAAG
GGCCGCTTCGGCGACGAGGCCTGGGGCCTGTTGGAGCAGTCGGTCGGCAAGCTGGCGTAG

Upstream 100 bases:

>100_bases
TCATTTTTCTTGTTTGACGCTTCACCACTCAACGCCTATCGTTGCGTGACTTTCACCCGATGATGCATCAAAACGCATCA
AAACAAAACTGGAGACAACC

Downstream 100 bases:

>100_bases
GTTTTCGAGCGCTCTCTTGCTCCCTCTCCCGCTGGGAGAGGGCAGGGGTGAGGGCCAGCGGCGGTTGACCAGGCCCCGCC
CCATGCGAAGAAGCCCTCAT

Product: TRAP dicarboxylate transporter subunit DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTEVTRRSVLRTLSAVPAAGIAAALPSMARAAEFSYKYGNNLPVTHPLNIRAQQAADRILKETNGRVEIKIFPNNQLGGD
TDMLAQVRSGGIEFFTPSALVIATLVPVAAINAVGFAFSDYNQVWGAMDGKLGAHVREAISKSRLYAFEKMWDNGFRQTT
SSKAPVTSAKDMDGLKIRVPVSPLSISMFKGLGAAPASLQFSEVYSSLQTKIVDAQENPLPIIQVAKLYEVQKFCSMTNH
IWDGYWFIANGRAWEKLPADLKTIVARAINEAGLQQRDDIKKLNETVAADLQSKGLAINRPASDSFRAKLREAGFYGEWK
GRFGDEAWGLLEQSVGKLA

Sequences:

>Translated_339_residues
MTEVTRRSVLRTLSAVPAAGIAAALPSMARAAEFSYKYGNNLPVTHPLNIRAQQAADRILKETNGRVEIKIFPNNQLGGD
TDMLAQVRSGGIEFFTPSALVIATLVPVAAINAVGFAFSDYNQVWGAMDGKLGAHVREAISKSRLYAFEKMWDNGFRQTT
SSKAPVTSAKDMDGLKIRVPVSPLSISMFKGLGAAPASLQFSEVYSSLQTKIVDAQENPLPIIQVAKLYEVQKFCSMTNH
IWDGYWFIANGRAWEKLPADLKTIVARAINEAGLQQRDDIKKLNETVAADLQSKGLAINRPASDSFRAKLREAGFYGEWK
GRFGDEAWGLLEQSVGKLA
>Mature_338_residues
TEVTRRSVLRTLSAVPAAGIAAALPSMARAAEFSYKYGNNLPVTHPLNIRAQQAADRILKETNGRVEIKIFPNNQLGGDT
DMLAQVRSGGIEFFTPSALVIATLVPVAAINAVGFAFSDYNQVWGAMDGKLGAHVREAISKSRLYAFEKMWDNGFRQTTS
SKAPVTSAKDMDGLKIRVPVSPLSISMFKGLGAAPASLQFSEVYSSLQTKIVDAQENPLPIIQVAKLYEVQKFCSMTNHI
WDGYWFIANGRAWEKLPADLKTIVARAINEAGLQQRDDIKKLNETVAADLQSKGLAINRPASDSFRAKLREAGFYGEWKG
RFGDEAWGLLEQSVGKLA

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=290, Percent_Identity=31.7241379310345, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 37071; Mature: 36940

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVTRRSVLRTLSAVPAAGIAAALPSMARAAEFSYKYGNNLPVTHPLNIRAQQAADRIL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
KETNGRVEIKIFPNNQLGGDTDMLAQVRSGGIEFFTPSALVIATLVPVAAINAVGFAFSD
HHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
YNQVWGAMDGKLGAHVREAISKSRLYAFEKMWDNGFRQTTSSKAPVTSAKDMDGLKIRVP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCEEEEC
VSPLSISMFKGLGAAPASLQFSEVYSSLQTKIVDAQENPLPIIQVAKLYEVQKFCSMTNH
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IWDGYWFIANGRAWEKLPADLKTIVARAINEAGLQQRDDIKKLNETVAADLQSKGLAINR
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEC
PASDSFRAKLREAGFYGEWKGRFGDEAWGLLEQSVGKLA
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEVTRRSVLRTLSAVPAAGIAAALPSMARAAEFSYKYGNNLPVTHPLNIRAQQAADRIL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
KETNGRVEIKIFPNNQLGGDTDMLAQVRSGGIEFFTPSALVIATLVPVAAINAVGFAFSD
HHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
YNQVWGAMDGKLGAHVREAISKSRLYAFEKMWDNGFRQTTSSKAPVTSAKDMDGLKIRVP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCEEEEC
VSPLSISMFKGLGAAPASLQFSEVYSSLQTKIVDAQENPLPIIQVAKLYEVQKFCSMTNH
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IWDGYWFIANGRAWEKLPADLKTIVARAINEAGLQQRDDIKKLNETVAADLQSKGLAINR
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEC
PASDSFRAKLREAGFYGEWKGRFGDEAWGLLEQSVGKLA
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA