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The map label for this gene is siaT [H]

Identifier: 91785947

GI number: 91785947

Start: 34935

End: 36818

Strand: Reverse

Name: siaT [H]

Synonym: Bpro_0034

Alternate gene names: 91785947

Gene position: 36818-34935 (Counterclockwise)

Preceding gene: 91785948

Following gene: 91785946

Centisome position: 0.71

GC content: 66.19

Gene sequence:

>1884_bases
ATGTCCCACGCCCCTTCTCCCGTCGCTGCCGATGCCCTGCCAGCCAATGCGCTGAGCGGCCTGGCCCACGGCGTGGACCG
GGGCCTGGGCGCGGTGGTCGAAACCATCGCAGCCGGGCTGGTGCTGGCCGAAATCATCGTGCTGTTCGCCGGCGTAGTCT
CGCGCTATGTCTTTCACCAGCCGCTGGTCTGGTCGGACGAGCTCGCGTCCATCATGTTTTTGTGGCTGTCCATGCTGGGC
GCCGTCGTCGCGCTGCGCCGCGGCGAACACATGCGCATGACGGCGCTGGTCAACCACGTCCAGCCGCACACCCGTGCCCT
GCTCGACACCGTGGCCATCACCGCCTCGCTCGCGTTTTTGGTGCTGGTGCTGTTTCCAGCCGGTGAATATGCCTATGAAG
AAACCTTCATCGTCACGCCGGCACTGGAGATCAGCAACGGCTGGCGCGCCTCGGCCATTCCGGTGGGCATGGGGCTGATG
ATCATCGTGGCCCTGCTGCGGCTGCTGCGCATCAGCAGCTTCCAGCAGATCGCCCTCGCGTTGGCCGGCACGGCCGCCGT
GGTGCTGGCCTTCTGGCTGGCGCAACCCCTGCTCGCGCCGCTGGGCAAGGTCAATCTGGTGATCTTCTTCGTGCTGGTGG
TGGCGGCCAATGTGTTCTCCGGCGTGCCGATTGCCTTCTCGTTCGCGCTGGCCACGTTTGGCTACCTCGCGCTCACCACC
CAAACCCCGCTGCTGGTCATGGTGGGCCGGCTCGACGAAGGCATGTCGCACCTGATCCTGCTGGCGGTGCCGCTGTTCAT
CTTCCTGGGCGCGCTGATCGAAATGACCGGCATGGCCAAGGCCATGATCCAGTTCCTGGCCAGCCTGCTGGGCCATGTGC
GCGGCGGCCTCAGCTATGTGCTGATCGGTGCCATGTACCTGGTGTCGGGCATCTCGGGCTCCAAGATCGCCGACATGGCC
GCGATTGCGCCGGTGCTTTTCCCTGAAATGAAAAAGCGCGGCGCCAAACCGGGCGACCTGGTGGCGCTGCTGTCGGCCAC
CGGCGCTCAGACCGAAACCATTCCGCCGTCGATCGTGCTGATCACGATCGGCTCGGTCACCGGTGTCTCGATAGCCGCGC
TGTTCACGGGCGGCCTGCTGCCAGCCGTGGTGCTGGGTGCCGCGCTGTGCGCCGTCGTCTGGTGGCGCTACCGTGGTGAA
GATCTGAGCGGCGTCACGCGCTACGGCAAACGCGAAATCGGCAAGCTGCTGCTGATCGCCCTGCCCGCCATCGTGCTGCC
CTTCGTGATTCGCGCGGCCGTCGTGGAAGGCGTGGCCACCGCCACCGAGGTCTCCACCATCGGCATCGTCTATTCGGTGC
TGGCCGGCTTGCTGCTGTACCGCCGGTTCGCGTGGCGCCGCCTCATGCCCATGCTGGTCGAAACCGCATCGCTGACCGGC
GCCATCATCTTCATCGTGGGCTGCGCCACCGCCATGGCCTGGGGCCTCACGCAGTCGGGCTTCTCGCAGGACCTGGCCGG
CATCATGGGCAGCCTGCCCGGCGGTGCCTACGGCTTTCTGGCCGTGTCCATCGTCGCCTTCATCGTGCTGGGCAGCGTGC
TGGAGGGCATTCCCGCCATCGTGCTGTTTGGCCCGCTGCTGTTTCCCATCGCCAAGGCGGCCGGCGTGCATGAAGTGCAC
TACGCCATGGTCGTGATCTTCGCCATGGGCATCGGCCTCTTCGCGCCGCCTTTCGGTGTCGGCTATTACGGCGCCTGCGC
GGTCAGCAAGGTCGACCCGGACGACGGCATCCCGCACATCTGGGCTTACTTCGGCGCCCTGCTGGTCGGCCTCATCGTGG
TCGCGGCCATTCCCTGGTTCTCCACCGGCTTCCTCAAAAACTAA

Upstream 100 bases:

>100_bases
CTCTCTTGCTCCCTCTCCCAGAGGGAGAAGGAGCAAGACAAGCAGCACCACCGCCCACTTTCCACGTCAGCGCAATTATT
TCTAATCCGGAGTCCCCTTC

Downstream 100 bases:

>100_bases
ATCCGGCACCAAAACTTCCCACCTCCCCCTTTCACTGGAGCGACAACACATGAGCAAATTCTTTGGCGAGATCCGCCAGC
TGGGCTACGTCGTGCACGAC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MSHAPSPVAADALPANALSGLAHGVDRGLGAVVETIAAGLVLAEIIVLFAGVVSRYVFHQPLVWSDELASIMFLWLSMLG
AVVALRRGEHMRMTALVNHVQPHTRALLDTVAITASLAFLVLVLFPAGEYAYEETFIVTPALEISNGWRASAIPVGMGLM
IIVALLRLLRISSFQQIALALAGTAAVVLAFWLAQPLLAPLGKVNLVIFFVLVVAANVFSGVPIAFSFALATFGYLALTT
QTPLLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIQFLASLLGHVRGGLSYVLIGAMYLVSGISGSKIADMA
AIAPVLFPEMKKRGAKPGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGLLPAVVLGAALCAVVWWRYRGE
DLSGVTRYGKREIGKLLLIALPAIVLPFVIRAAVVEGVATATEVSTIGIVYSVLAGLLLYRRFAWRRLMPMLVETASLTG
AIIFIVGCATAMAWGLTQSGFSQDLAGIMGSLPGGAYGFLAVSIVAFIVLGSVLEGIPAIVLFGPLLFPIAKAAGVHEVH
YAMVVIFAMGIGLFAPPFGVGYYGACAVSKVDPDDGIPHIWAYFGALLVGLIVVAAIPWFSTGFLKN

Sequences:

>Translated_627_residues
MSHAPSPVAADALPANALSGLAHGVDRGLGAVVETIAAGLVLAEIIVLFAGVVSRYVFHQPLVWSDELASIMFLWLSMLG
AVVALRRGEHMRMTALVNHVQPHTRALLDTVAITASLAFLVLVLFPAGEYAYEETFIVTPALEISNGWRASAIPVGMGLM
IIVALLRLLRISSFQQIALALAGTAAVVLAFWLAQPLLAPLGKVNLVIFFVLVVAANVFSGVPIAFSFALATFGYLALTT
QTPLLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIQFLASLLGHVRGGLSYVLIGAMYLVSGISGSKIADMA
AIAPVLFPEMKKRGAKPGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGLLPAVVLGAALCAVVWWRYRGE
DLSGVTRYGKREIGKLLLIALPAIVLPFVIRAAVVEGVATATEVSTIGIVYSVLAGLLLYRRFAWRRLMPMLVETASLTG
AIIFIVGCATAMAWGLTQSGFSQDLAGIMGSLPGGAYGFLAVSIVAFIVLGSVLEGIPAIVLFGPLLFPIAKAAGVHEVH
YAMVVIFAMGIGLFAPPFGVGYYGACAVSKVDPDDGIPHIWAYFGALLVGLIVVAAIPWFSTGFLKN
>Mature_626_residues
SHAPSPVAADALPANALSGLAHGVDRGLGAVVETIAAGLVLAEIIVLFAGVVSRYVFHQPLVWSDELASIMFLWLSMLGA
VVALRRGEHMRMTALVNHVQPHTRALLDTVAITASLAFLVLVLFPAGEYAYEETFIVTPALEISNGWRASAIPVGMGLMI
IVALLRLLRISSFQQIALALAGTAAVVLAFWLAQPLLAPLGKVNLVIFFVLVVAANVFSGVPIAFSFALATFGYLALTTQ
TPLLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIQFLASLLGHVRGGLSYVLIGAMYLVSGISGSKIADMAA
IAPVLFPEMKKRGAKPGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGLLPAVVLGAALCAVVWWRYRGED
LSGVTRYGKREIGKLLLIALPAIVLPFVIRAAVVEGVATATEVSTIGIVYSVLAGLLLYRRFAWRRLMPMLVETASLTGA
IIFIVGCATAMAWGLTQSGFSQDLAGIMGSLPGGAYGFLAVSIVAFIVLGSVLEGIPAIVLFGPLLFPIAKAAGVHEVHY
AMVVIFAMGIGLFAPPFGVGYYGACAVSKVDPDDGIPHIWAYFGALLVGLIVVAAIPWFSTGFLKN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=377, Percent_Identity=27.8514588859416, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65685; Mature: 65553

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAPSPVAADALPANALSGLAHGVDRGLGAVVETIAAGLVLAEIIVLFAGVVSRYVFHQ
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLVWSDELASIMFLWLSMLGAVVALRRGEHMRMTALVNHVQPHTRALLDTVAITASLAFL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VLVLFPAGEYAYEETFIVTPALEISNGWRASAIPVGMGLMIIVALLRLLRISSFQQIALA
HHHHHCCCCHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGTAAVVLAFWLAQPLLAPLGKVNLVIFFVLVVAANVFSGVPIAFSFALATFGYLALTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
QTPLLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIQFLASLLGHVRGGLSYV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LIGAMYLVSGISGSKIADMAAIAPVLFPEMKKRGAKPGDLVALLSATGAQTETIPPSIVL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEE
ITIGSVTGVSIAALFTGGLLPAVVLGAALCAVVWWRYRGEDLSGVTRYGKREIGKLLLIA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LPAIVLPFVIRAAVVEGVATATEVSTIGIVYSVLAGLLLYRRFAWRRLMPMLVETASLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIIFIVGCATAMAWGLTQSGFSQDLAGIMGSLPGGAYGFLAVSIVAFIVLGSVLEGIPAI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLFGPLLFPIAKAAGVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAVSKVDPDDGIPHI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCCCHH
WAYFGALLVGLIVVAAIPWFSTGFLKN
HHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SHAPSPVAADALPANALSGLAHGVDRGLGAVVETIAAGLVLAEIIVLFAGVVSRYVFHQ
CCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLVWSDELASIMFLWLSMLGAVVALRRGEHMRMTALVNHVQPHTRALLDTVAITASLAFL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VLVLFPAGEYAYEETFIVTPALEISNGWRASAIPVGMGLMIIVALLRLLRISSFQQIALA
HHHHHCCCCHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGTAAVVLAFWLAQPLLAPLGKVNLVIFFVLVVAANVFSGVPIAFSFALATFGYLALTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
QTPLLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIQFLASLLGHVRGGLSYV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LIGAMYLVSGISGSKIADMAAIAPVLFPEMKKRGAKPGDLVALLSATGAQTETIPPSIVL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEE
ITIGSVTGVSIAALFTGGLLPAVVLGAALCAVVWWRYRGEDLSGVTRYGKREIGKLLLIA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LPAIVLPFVIRAAVVEGVATATEVSTIGIVYSVLAGLLLYRRFAWRRLMPMLVETASLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIIFIVGCATAMAWGLTQSGFSQDLAGIMGSLPGGAYGFLAVSIVAFIVLGSVLEGIPAI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLFGPLLFPIAKAAGVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAVSKVDPDDGIPHI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCCCHH
WAYFGALLVGLIVVAAIPWFSTGFLKN
HHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]