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The map label for this gene is ubiB [H]

Identifier: 91785930

GI number: 91785930

Start: 16482

End: 18260

Strand: Reverse

Name: ubiB [H]

Synonym: Bpro_0017

Alternate gene names: 91785930

Gene position: 18260-16482 (Counterclockwise)

Preceding gene: 91785931

Following gene: 91785928

Centisome position: 0.35

GC content: 68.58

Gene sequence:

>1779_bases
ATGACGCAAAAGACGCGGTTTTATGTCCCAGATAGCGTGCAACACTGCACTTGGACAAGGCAGCGCTATCATCGGCCCAT
GCTGCTCGAAACCCTGGGCGCGGCGCGCGAAATCGGTCGCATCAACGAGATTGCCGGTGTGCTCATTCGCCACGGCTTTG
GCGACACCGTGCGCCGCCTGGGCCTGGCCGACCGGCTCGAACGGGCCGGCCATATCGTCAAGTGGGAGCACGCCGCCGAC
CTCGCCCGCCTTGAGCCGCCGGTGCAGGTGCGCCTGGCGCTCGAAGAGCTGGGCCCCACCTTCGTCAAGCTCGGGCAGAT
CCTGGCCGGCCGCGCCGACCTGCTCGGCCCCGAATGGATTGCCGAGCTTCAGCGCCTGCACAGCCAGGTGCCCGCCGTGC
CGCTGGACGACCTGCGCCCGCAGTTGCGGGAAGACCTGGGCGACGAGCCCGAAAACATCTTTGCCCGCTTTGACGTGGAG
CCGCTGGCGGCAGCGTCCATTGCCCAGGTGCACCGGGCGCAGCTCCACGACGGCAGCGAAGTGGTCGTCAAGATTCGCCG
CCCCGGCATCCGCGAGGTGATCGAGGCCGACCTGCGGCTGCTGGACCGCCTGGCCGCCATCGCCGAGGCCGACATGCCCT
CCCTCAAGCCCTACCGCCCGCGCCGGCTGGTGCGGGAGTTCGCGCGTTCGCTGCGCCGCGAGCTGGACCTCGCCGTCGAG
TGCCACAACGCCGAGCGCGTGGCCGACAACTTTGCGCAAACGCCGCATGTGCTGATTCCGCGCGTGCACTGGGCCCACAC
CAGCGAGCGCATCAACACCCAGGACTTCGTCGACGGCATCCCCGGCGAGCGGCTCGACCTGCTGCCCGCCGATGCCGGCT
TCGACCGCACCGTTCTGGCGCAGCGCGGCGCCCGGGCCGTGCTGAAAATGATTGTGGAAGACGGCTTTTTTCACGCCGAC
CCGCACCCCGGCAATGTGTTCTACCTGCCGGGCAACCGCATCGCGTTCATCGACTTCGGCATGGTCGGCAGCCTGTCGCC
GCAGCGGCGCGAGGAACTGCTGCAACTGCTGCTGGGCCTGGTCACGCGCGACGCCCAGGCCGTGGCCACCGTGCTGCTGG
ACTGGGCCGGCGATGACCACGGCCAGAGCCTCTCGCAGCTCGAAACCGAAATTGAGGCTTTTGTCGACCAGTACCACGGT
TCACCACTGGCGCAACTCAACCTCGGCGAGATGCTGACCCGCATCACTACCCTCCTGCGCGAGCACCACCTCACCCTACC
CCCGGATCTGGCCTTGCTGATCAAGGCCTTCATCTCGCTGGAAGGCATGGGCCGCGGCCTGGACCCCGGCTTTCACATGG
CCACGGAAGCCATGCCCCTGCTGCAGGAGGTGGCGCGCGCACGCTACCAGCCCGGGGCCATCGCCGCCCGCGGCTGGAAA
ACACTGCTTCGCGCGCTCAGGCTGGCCGAGCAACTGCCGCACGACCTGTCGCGCCTGCTGCGCAATGCGCGCCGCGGTCA
ACTCCGGGTGAGCATCGAAGTGACCCACCTCAAACGGGTAGGTGACCAGCTGGACCGCGCGGCCAACCGGCTGGCCATGG
CCCTGGTGATCGCCGCGCTCATCATCGGCTCGTCCATCGTGATGACCGTGCGGGGCGGCCCCACCCTGTTTGGCCTGCCG
GTCTTCGGCTTTCTGGGCTTTTGCGGCGCGGTGGCCTGCGCCCTGTGGCTGGTGCGCGCCATCTGGCGCAGCAGCCGGCC
GCAGGACGACGACGCCTGA

Upstream 100 bases:

>100_bases
GCATGCTTGATGGGACCCATAAAAGCGATGGATTTTGGGTCAGGGCAAGGCGCAAACCACAGCGATACCCGCCGGTATCG
CGCGGATTTGCAACGCCGCC

Downstream 100 bases:

>100_bases
GCCGGCCGCCGGCGCTGCGGCCGCTGGAGACAAGCGCATGACAAGCGCATAAAAAAACACCCGCCTTTGGGGGCGGGTGT
TCCTGGGGTGCAAGGGTTGT

Product: 2-octaprenylphenol hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MTQKTRFYVPDSVQHCTWTRQRYHRPMLLETLGAAREIGRINEIAGVLIRHGFGDTVRRLGLADRLERAGHIVKWEHAAD
LARLEPPVQVRLALEELGPTFVKLGQILAGRADLLGPEWIAELQRLHSQVPAVPLDDLRPQLREDLGDEPENIFARFDVE
PLAAASIAQVHRAQLHDGSEVVVKIRRPGIREVIEADLRLLDRLAAIAEADMPSLKPYRPRRLVREFARSLRRELDLAVE
CHNAERVADNFAQTPHVLIPRVHWAHTSERINTQDFVDGIPGERLDLLPADAGFDRTVLAQRGARAVLKMIVEDGFFHAD
PHPGNVFYLPGNRIAFIDFGMVGSLSPQRREELLQLLLGLVTRDAQAVATVLLDWAGDDHGQSLSQLETEIEAFVDQYHG
SPLAQLNLGEMLTRITTLLREHHLTLPPDLALLIKAFISLEGMGRGLDPGFHMATEAMPLLQEVARARYQPGAIAARGWK
TLLRALRLAEQLPHDLSRLLRNARRGQLRVSIEVTHLKRVGDQLDRAANRLAMALVIAALIIGSSIVMTVRGGPTLFGLP
VFGFLGFCGAVACALWLVRAIWRSSRPQDDDA

Sequences:

>Translated_592_residues
MTQKTRFYVPDSVQHCTWTRQRYHRPMLLETLGAAREIGRINEIAGVLIRHGFGDTVRRLGLADRLERAGHIVKWEHAAD
LARLEPPVQVRLALEELGPTFVKLGQILAGRADLLGPEWIAELQRLHSQVPAVPLDDLRPQLREDLGDEPENIFARFDVE
PLAAASIAQVHRAQLHDGSEVVVKIRRPGIREVIEADLRLLDRLAAIAEADMPSLKPYRPRRLVREFARSLRRELDLAVE
CHNAERVADNFAQTPHVLIPRVHWAHTSERINTQDFVDGIPGERLDLLPADAGFDRTVLAQRGARAVLKMIVEDGFFHAD
PHPGNVFYLPGNRIAFIDFGMVGSLSPQRREELLQLLLGLVTRDAQAVATVLLDWAGDDHGQSLSQLETEIEAFVDQYHG
SPLAQLNLGEMLTRITTLLREHHLTLPPDLALLIKAFISLEGMGRGLDPGFHMATEAMPLLQEVARARYQPGAIAARGWK
TLLRALRLAEQLPHDLSRLLRNARRGQLRVSIEVTHLKRVGDQLDRAANRLAMALVIAALIIGSSIVMTVRGGPTLFGLP
VFGFLGFCGAVACALWLVRAIWRSSRPQDDDA
>Mature_591_residues
TQKTRFYVPDSVQHCTWTRQRYHRPMLLETLGAAREIGRINEIAGVLIRHGFGDTVRRLGLADRLERAGHIVKWEHAADL
ARLEPPVQVRLALEELGPTFVKLGQILAGRADLLGPEWIAELQRLHSQVPAVPLDDLRPQLREDLGDEPENIFARFDVEP
LAAASIAQVHRAQLHDGSEVVVKIRRPGIREVIEADLRLLDRLAAIAEADMPSLKPYRPRRLVREFARSLRRELDLAVEC
HNAERVADNFAQTPHVLIPRVHWAHTSERINTQDFVDGIPGERLDLLPADAGFDRTVLAQRGARAVLKMIVEDGFFHADP
HPGNVFYLPGNRIAFIDFGMVGSLSPQRREELLQLLLGLVTRDAQAVATVLLDWAGDDHGQSLSQLETEIEAFVDQYHGS
PLAQLNLGEMLTRITTLLREHHLTLPPDLALLIKAFISLEGMGRGLDPGFHMATEAMPLLQEVARARYQPGAIAARGWKT
LLRALRLAEQLPHDLSRLLRNARRGQLRVSIEVTHLKRVGDQLDRAANRLAMALVIAALIIGSSIVMTVRGGPTLFGLPV
FGFLGFCGAVACALWLVRAIWRSSRPQDDDA

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=274, Percent_Identity=34.3065693430657, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=33.9483394833948, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI217035081, Length=233, Percent_Identity=32.618025751073, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI34147522, Length=336, Percent_Identity=25.8928571428571, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI27363457, Length=348, Percent_Identity=24.4252873563218, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI217416386, Length=307, Percent_Identity=25.4071661237785, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI2367309, Length=509, Percent_Identity=31.6306483300589, Blast_Score=213, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17559152, Length=279, Percent_Identity=29.3906810035842, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32565180, Length=373, Percent_Identity=23.8605898123324, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325148, Length=434, Percent_Identity=24.6543778801843, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323282, Length=247, Percent_Identity=29.5546558704453, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22024280, Length=273, Percent_Identity=31.5018315018315, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24662575, Length=279, Percent_Identity=30.4659498207885, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18859849, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 66066; Mature: 65935

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKTRFYVPDSVQHCTWTRQRYHRPMLLETLGAAREIGRINEIAGVLIRHGFGDTVRRL
CCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLADRLERAGHIVKWEHAADLARLEPPVQVRLALEELGPTFVKLGQILAGRADLLGPEWI
HHHHHHHHCCCEEEEHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCHHHCCCHHHH
AELQRLHSQVPAVPLDDLRPQLREDLGDEPENIFARFDVEPLAAASIAQVHRAQLHDGSE
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHHHCCCCCC
VVVKIRRPGIREVIEADLRLLDRLAAIAEADMPSLKPYRPRRLVREFARSLRRELDLAVE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHE
CHNAERVADNFAQTPHVLIPRVHWAHTSERINTQDFVDGIPGERLDLLPADAGFDRTVLA
ECCHHHHHHHHHCCCCEEECCCHHHCCHHCCCHHHHHCCCCCCCEECCCCCCCCCHHHHH
QRGARAVLKMIVEDGFFHADPHPGNVFYLPGNRIAFIDFGMVGSLSPQRREELLQLLLGL
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
VTRDAQAVATVLLDWAGDDHGQSLSQLETEIEAFVDQYHGSPLAQLNLGEMLTRITTLLR
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHH
EHHLTLPPDLALLIKAFISLEGMGRGLDPGFHMATEAMPLLQEVARARYQPGAIAARGWK
HCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TLLRALRLAEQLPHDLSRLLRNARRGQLRVSIEVTHLKRVGDQLDRAANRLAMALVIAAL
HHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGSSIVMTVRGGPTLFGLPVFGFLGFCGAVACALWLVRAIWRSSRPQDDDA
HHCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQKTRFYVPDSVQHCTWTRQRYHRPMLLETLGAAREIGRINEIAGVLIRHGFGDTVRRL
CCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLADRLERAGHIVKWEHAADLARLEPPVQVRLALEELGPTFVKLGQILAGRADLLGPEWI
HHHHHHHHCCCEEEEHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCHHHCCCHHHH
AELQRLHSQVPAVPLDDLRPQLREDLGDEPENIFARFDVEPLAAASIAQVHRAQLHDGSE
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHHHCCCCCC
VVVKIRRPGIREVIEADLRLLDRLAAIAEADMPSLKPYRPRRLVREFARSLRRELDLAVE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHE
CHNAERVADNFAQTPHVLIPRVHWAHTSERINTQDFVDGIPGERLDLLPADAGFDRTVLA
ECCHHHHHHHHHCCCCEEECCCHHHCCHHCCCHHHHHCCCCCCCEECCCCCCCCCHHHHH
QRGARAVLKMIVEDGFFHADPHPGNVFYLPGNRIAFIDFGMVGSLSPQRREELLQLLLGL
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
VTRDAQAVATVLLDWAGDDHGQSLSQLETEIEAFVDQYHGSPLAQLNLGEMLTRITTLLR
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHH
EHHLTLPPDLALLIKAFISLEGMGRGLDPGFHMATEAMPLLQEVARARYQPGAIAARGWK
HCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TLLRALRLAEQLPHDLSRLLRNARRGQLRVSIEVTHLKRVGDQLDRAANRLAMALVIAAL
HHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGSSIVMTVRGGPTLFGLPVFGFLGFCGAVACALWLVRAIWRSSRPQDDDA
HHCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]