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The map label for this gene is minE

Identifier: 91785931

GI number: 91785931

Start: 18471

End: 18731

Strand: Reverse

Name: minE

Synonym: Bpro_0018

Alternate gene names: 91785931

Gene position: 18731-18471 (Counterclockwise)

Preceding gene: 91785932

Following gene: 91785930

Centisome position: 0.36

GC content: 59.77

Gene sequence:

>261_bases
ATGGCTTCATTCCTGTCCTTCCTGCTCGGCGAAAAGAAACAAACCGCCAGCGTCGCCAAGGAGCGGCTGCAGATCATCCT
GGCGCACGAGCGCACCGGCCGCAGCCACAAGCCCGACTACCTGCCGGCGCTGCAGCGCGACCTGATTGCGGTCATCGCCA
AATACATTCACATCAACCCCAACGACATCAAGCTCCACCTGGAGCGCCAGGACAACCTCGATGTGCTGGAAGTGAAGATC
GAGCTGCCGGACGCAAAGTAA

Upstream 100 bases:

>100_bases
GTGGTCGACCGCTTCCTCGGCGACAAGGACAAGCCGCTGCGCTTCATCGACGCGCAAAAGCCCGGCCTGCTGAAACGCTG
GTTTGGAGGAAAGTGACACG

Downstream 100 bases:

>100_bases
ACCCGGGCGTCCGCCAAGTCTGCCCGCCAAACCCGCTCGCTATCGAATGCGTAGCTGACGACCGGGCTCCTGCGCCAACT
TGCGCCAGGTCAACCACCTG

Product: cell division topological specificity factor MinE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MASFLSFLLGEKKQTASVAKERLQIILAHERTGRSHKPDYLPALQRDLIAVIAKYIHINPNDIKLHLERQDNLDVLEVKI
ELPDAK

Sequences:

>Translated_86_residues
MASFLSFLLGEKKQTASVAKERLQIILAHERTGRSHKPDYLPALQRDLIAVIAKYIHINPNDIKLHLERQDNLDVLEVKI
ELPDAK
>Mature_85_residues
ASFLSFLLGEKKQTASVAKERLQIILAHERTGRSHKPDYLPALQRDLIAVIAKYIHINPNDIKLHLERQDNLDVLEVKIE
LPDAK

Specific function: Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the l

COG id: COG0851

COG function: function code D; Septum formation topological specificity factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minE family

Homologues:

Organism=Escherichia coli, GI1787422, Length=85, Percent_Identity=44.7058823529412, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINE_POLSJ (Q12HK7)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_546883.1
- ProteinModelPortal:   Q12HK7
- SMR:   Q12HK7
- STRING:   Q12HK7
- GeneID:   4011754
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_0018
- NMPDR:   fig|296591.1.peg.4961
- eggNOG:   COG0851
- HOGENOM:   HBG449956
- OMA:   HERSGRN
- PhylomeDB:   Q12HK7
- ProtClustDB:   PRK13989
- BioCyc:   PSP296591:BPRO_0018-MONOMER
- HAMAP:   MF_00262
- InterPro:   IPR005527
- TIGRFAMs:   TIGR01215

Pfam domain/function: PF03776 MinE

EC number: NA

Molecular weight: Translated: 9840; Mature: 9708

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFLSFLLGEKKQTASVAKERLQIILAHERTGRSHKPDYLPALQRDLIAVIAKYIHINP
CHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
NDIKLHLERQDNLDVLEVKIELPDAK
CCEEEEEECCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
ASFLSFLLGEKKQTASVAKERLQIILAHERTGRSHKPDYLPALQRDLIAVIAKYIHINP
HHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
NDIKLHLERQDNLDVLEVKIELPDAK
CCEEEEEECCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA