Click here to switch to the map view.

The map label for this gene is dsdC [H]

Identifier: 91213905

GI number: 91213905

Start: 4864027

End: 4864977

Strand: Direct

Name: dsdC [H]

Synonym: UTI89_C4957

Alternate gene names: 91213905

Gene position: 4864027-4864977 (Clockwise)

Preceding gene: 91213880

Following gene: 91213919

Centisome position: 96.02

GC content: 48.37

Gene sequence:

>951_bases
GTGATTATGGAACCCCTTCGTGAAATAAGAAATCGACTGCTTAACGGCTGGCAACTATCAAAACTGCATACTTTTGAAGT
GGCTGCCAGGCATCAGTCCTTCGCTCTCGCGGCAGAGGAATTGTCGCTGAGCCCCAGTGCGGTAAGTCACCGTATCAATC
AGCTGGAAGAAGAATTAGGTATTCAGTTGTTTGTTCGTTCCCATCGCAAAGTGGAATTAACGCACGAGGGGAAACGCGTT
TATTGGGCGCTAAAATCGTCGCTGGATACCCTGAACCAGGAAATTCTTGATATCAAAAATCAGGAATTATCGGGAACGTT
AACGCTGTATTCCCGGCCCTCTATCGCCCAATGCTGGTTGGTGCCCGCATTAGGTGACTTTACACGCCGCTATCCGTCTA
TTTCGCTCACCGTGCTCACCGGTAATGACAATGTCAATTTGCAACGTGCCGGAATCGATTTGGCAATCTACTTTGATGAC
GCGCCGTCAGCGCAACTGACTCATCACTTTCTGATGGATGAAGAAATCCTGCCTGTATGTAGCCCGGAATACGCTCAAAG
ACATGCTTTAACCAACCAGGTAATTAACCTTCGCCACTGTACGTTGCTCCATGACAGACAGGCCTGGAGCAACGACTCCG
GTACGGATGAATGGCATAGTTGGGCGCAACATTATGCGGTTAATTTGCCGACATCTTCGGGAATTGGCTTTGATCGTTCT
GATTTAGCTGTTATCGCCGCGATGAATCATATTGGGGTGGCGATGGGAAGGAAACGCCTGGTACAAAAAAGACTTATCAG
TGGTGAGCTCGTCGCGCCGTTTGGCGATATGACGGTGAAATGCCATCAGCATTATTACATCACCACATTACCGGGCAGGC
AGTGGCCAAAAATTGAGGCATTTATTACCTGGCTAAGAGAGCAGGTATGTCAGTCTTGTCAGTATCAGTGA

Upstream 100 bases:

>100_bases
TTACATCTAAAAATGAAGGTGAATTGAGATATGGTTCACTTTAGCTCACCTTACAGCTGAAATTTTGCCGCTATTTTTTT
ACACTTAAGAGAAAAATGAG

Downstream 100 bases:

>100_bases
TACCGGGGATACCGGGGATACCGGGGATACCGGGGATACCGACAATATGGAAGGGCTCATTGCCCTGAAAACAACATTGG
TGTCGGATGTACCGGGCCGC

Product: DNA-binding transcriptional regulator DsdC

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIMEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPSAVSHRINQLEEELGIQLFVRSHRKVELTHEGKRV
YWALKSSLDTLNQEILDIKNQELSGTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDD
APSAQLTHHFLMDEEILPVCSPEYAQRHALTNQVINLRHCTLLHDRQAWSNDSGTDEWHSWAQHYAVNLPTSSGIGFDRS
DLAVIAAMNHIGVAMGRKRLVQKRLISGELVAPFGDMTVKCHQHYYITTLPGRQWPKIEAFITWLREQVCQSCQYQ

Sequences:

>Translated_316_residues
MIMEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPSAVSHRINQLEEELGIQLFVRSHRKVELTHEGKRV
YWALKSSLDTLNQEILDIKNQELSGTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDD
APSAQLTHHFLMDEEILPVCSPEYAQRHALTNQVINLRHCTLLHDRQAWSNDSGTDEWHSWAQHYAVNLPTSSGIGFDRS
DLAVIAAMNHIGVAMGRKRLVQKRLISGELVAPFGDMTVKCHQHYYITTLPGRQWPKIEAFITWLREQVCQSCQYQ
>Mature_316_residues
MIMEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPSAVSHRINQLEEELGIQLFVRSHRKVELTHEGKRV
YWALKSSLDTLNQEILDIKNQELSGTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDD
APSAQLTHHFLMDEEILPVCSPEYAQRHALTNQVINLRHCTLLHDRQAWSNDSGTDEWHSWAQHYAVNLPTSSGIGFDRS
DLAVIAAMNHIGVAMGRKRLVQKRLISGELVAPFGDMTVKCHQHYYITTLPGRQWPKIEAFITWLREQVCQSCQYQ

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=307, Percent_Identity=98.371335504886, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=33.6700336700337, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=31.25, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787128, Length=307, Percent_Identity=27.3615635179153, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=25.3378378378378, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081978, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693105, Length=168, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693193, Length=178, Percent_Identity=30.3370786516854, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788748, Length=169, Percent_Identity=28.4023668639053, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789440, Length=203, Percent_Identity=28.0788177339901, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787589, Length=248, Percent_Identity=27.8225806451613, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=143, Percent_Identity=32.1678321678322, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=32.9479768786127, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082132, Length=284, Percent_Identity=25.3521126760563, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=176, Percent_Identity=28.4090909090909, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=141, Percent_Identity=29.0780141843972, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36093; Mature: 36093

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPSAVSHRINQLEEELG
CCCHHHHHHHHHHCCCEEECCEEHHHHHHHHHHHHEEHHHHCCCHHHHHHHHHHHHHHHC
IQLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELSGTLTLYSRPSIAQCWL
EEEEEECCCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHEEE
VPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAPSAQLTHHFLMDEEILPVC
EHHHHHHHHHCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCCCCCCC
SPEYAQRHALTNQVINLRHCTLLHDRQAWSNDSGTDEWHSWAQHYAVNLPTSSGIGFDRS
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCC
DLAVIAAMNHIGVAMGRKRLVQKRLISGELVAPFGDMTVKCHQHYYITTLPGRQWPKIEA
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECEEEEEECCCCCCCHHHH
FITWLREQVCQSCQYQ
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIMEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPSAVSHRINQLEEELG
CCCHHHHHHHHHHCCCEEECCEEHHHHHHHHHHHHEEHHHHCCCHHHHHHHHHHHHHHHC
IQLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELSGTLTLYSRPSIAQCWL
EEEEEECCCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHEEE
VPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAPSAQLTHHFLMDEEILPVC
EHHHHHHHHHCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCCCCCCC
SPEYAQRHALTNQVINLRHCTLLHDRQAWSNDSGTDEWHSWAQHYAVNLPTSSGIGFDRS
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCC
DLAVIAAMNHIGVAMGRKRLVQKRLISGELVAPFGDMTVKCHQHYYITTLPGRQWPKIEA
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECEEEEEECCCCCCCHHHH
FITWLREQVCQSCQYQ
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]