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The map label for this gene is resE [H]

Identifier: 91213880

GI number: 91213880

Start: 4832303

End: 4833775

Strand: Direct

Name: resE [H]

Synonym: UTI89_C4932

Alternate gene names: 91213880

Gene position: 4832303-4833775 (Clockwise)

Preceding gene: 91213879

Following gene: 91213905

Centisome position: 95.39

GC content: 46.91

Gene sequence:

>1473_bases
ATGAATTGTAGCCTGACATTAAGCCAGAGGTTAAGCCTAGTATTTACAGTCGTTTTGCTGTTTTGCGCAGCAGTGACATG
TGGCGTTCATATTTACAGCAGTAATCTGTATGGCAATGCAATGGTACAGCGTTTATCTGCAGGGCTGGCGCAACAGATTG
TCATCACGGAGTCTCTGCTGGATAATCGTGGGCAGGTGAATCACCGGACATTAAAGAGTCTGTTTGAGCGTCTGATGACG
CTTAATCCCAGTGTGGAGCTGTATATTGTCTCGCCGGAAGGTCGGCTGCTTGTGGAGGCCGCCCCTCCAGGTCATATCAA
ACGTCGGTATATCAATATAGCGCCCTTGAAAAAATTTCTCTCCGGTGCTGTCTGGCCCGTATATGGTGATGATCCCCGAA
GTGTAAATAAGAAAAAAGTTTTCAGTACCGCACCGCTTTACCTGAGGGATGATCTGAAAGGATATCTGTATATTATTTTA
CAGGGAGAGGAACTTAATGCTCTTACTGATGCAGCCTGGACAAAGGCACTATGGAATGCACTGTACTGGTCGCTGTTTCT
GGTAGTGATATGTGGTCTGCTGTCGGGTATGCTGGTCTGGTACTGGGTAACCCGTCCCATACAGCAACTAACTGAAAATG
TCAGCGGGATAGAGCAGGACAGTATTAGTGCCATTAAACAACTGGCAATTCAGCGCCCTGCCACCCCCCCTAGCAACGAG
GTCGAGATATTACACAATGCCTTCATTGAACTGGCCCGTAAAATATCCTGTCAGTGGGATCAACTTTCAGAAAGTGATCA
ACAGCGCCGTGAATTTATTGCCAATATCTCCCATGATTTACGGACGCCATTAACATCACTTCTGGGATATCTGGAAACCC
TGTCAATGAAGTCGGATTCGCTATCATCAGAGGACTGTCATAAATATCTGACAACAGCTCTCCGGCAGGGACACAAGGTG
AGGCATCTGTCCTGTCAGCTTTTTGAGCTGGCACGTCTTGAGCATGGTGCTATAAAACCTCAACTGGAGCAATTTTCTGT
CTGTGAACTTATTCAGGATGTAGCTCAAAAATTTGAGCTCAGCATAGAAACCCGTCGATTGCAACTAAGAATTATGATGT
CACATTCCCTGCCTCTTATCAGGGCAGATATTTCAATGATAGAGCGTGTGATAACAAATTTACTGGATAATGCTGTACGC
CACACACCTCCGGAAGGCTCGATCAGGCTGAAAGTCTGGCAGGAAGATAATCGGTTGCACGTCGAAGTGGCTGACAGCGG
CCCTGGACTAACTGAAGATATGCGAACTCATCTTTTCCGGCGGGCATCAGTGTTATGTCATGAACCGTCAGAAGAGCCCC
GGGGAGGACTGGGATTGCTGATTGTACGCAGGATGCTGGTACTACACGGTGGTGATATCAGGTTGACTGATTCAACGACT
GGAGCCTGCTTTCGTTTTTTTCTTCCATTATAA

Upstream 100 bases:

>100_bases
TCGTGCCAAAATTGAACAGGATGCAGCAGAGCCAAAGATGATCCAGACCGTCTGGGGAAAAGGGTATAGGTTTTCAGTTG
ACAATGCAGGAATGCGATAA

Downstream 100 bases:

>100_bases
CATCAGGCGGCATATTTTGGGGTGGTTATGTGTATCTGCCTTTGTAAAAGGGATACAAGTTCTGTAGTGGAGCACAAAAT
CAGGACACCGGAATAACCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNCSLTLSQRLSLVFTVVLLFCAAVTCGVHIYSSNLYGNAMVQRLSAGLAQQIVITESLLDNRGQVNHRTLKSLFERLMT
LNPSVELYIVSPEGRLLVEAAPPGHIKRRYINIAPLKKFLSGAVWPVYGDDPRSVNKKKVFSTAPLYLRDDLKGYLYIIL
QGEELNALTDAAWTKALWNALYWSLFLVVICGLLSGMLVWYWVTRPIQQLTENVSGIEQDSISAIKQLAIQRPATPPSNE
VEILHNAFIELARKISCQWDQLSESDQQRREFIANISHDLRTPLTSLLGYLETLSMKSDSLSSEDCHKYLTTALRQGHKV
RHLSCQLFELARLEHGAIKPQLEQFSVCELIQDVAQKFELSIETRRLQLRIMMSHSLPLIRADISMIERVITNLLDNAVR
HTPPEGSIRLKVWQEDNRLHVEVADSGPGLTEDMRTHLFRRASVLCHEPSEEPRGGLGLLIVRRMLVLHGGDIRLTDSTT
GACFRFFLPL

Sequences:

>Translated_490_residues
MNCSLTLSQRLSLVFTVVLLFCAAVTCGVHIYSSNLYGNAMVQRLSAGLAQQIVITESLLDNRGQVNHRTLKSLFERLMT
LNPSVELYIVSPEGRLLVEAAPPGHIKRRYINIAPLKKFLSGAVWPVYGDDPRSVNKKKVFSTAPLYLRDDLKGYLYIIL
QGEELNALTDAAWTKALWNALYWSLFLVVICGLLSGMLVWYWVTRPIQQLTENVSGIEQDSISAIKQLAIQRPATPPSNE
VEILHNAFIELARKISCQWDQLSESDQQRREFIANISHDLRTPLTSLLGYLETLSMKSDSLSSEDCHKYLTTALRQGHKV
RHLSCQLFELARLEHGAIKPQLEQFSVCELIQDVAQKFELSIETRRLQLRIMMSHSLPLIRADISMIERVITNLLDNAVR
HTPPEGSIRLKVWQEDNRLHVEVADSGPGLTEDMRTHLFRRASVLCHEPSEEPRGGLGLLIVRRMLVLHGGDIRLTDSTT
GACFRFFLPL
>Mature_490_residues
MNCSLTLSQRLSLVFTVVLLFCAAVTCGVHIYSSNLYGNAMVQRLSAGLAQQIVITESLLDNRGQVNHRTLKSLFERLMT
LNPSVELYIVSPEGRLLVEAAPPGHIKRRYINIAPLKKFLSGAVWPVYGDDPRSVNKKKVFSTAPLYLRDDLKGYLYIIL
QGEELNALTDAAWTKALWNALYWSLFLVVICGLLSGMLVWYWVTRPIQQLTENVSGIEQDSISAIKQLAIQRPATPPSNE
VEILHNAFIELARKISCQWDQLSESDQQRREFIANISHDLRTPLTSLLGYLETLSMKSDSLSSEDCHKYLTTALRQGHKV
RHLSCQLFELARLEHGAIKPQLEQFSVCELIQDVAQKFELSIETRRLQLRIMMSHSLPLIRADISMIERVITNLLDNAVR
HTPPEGSIRLKVWQEDNRLHVEVADSGPGLTEDMRTHLFRRASVLCHEPSEEPRGGLGLLIVRRMLVLHGGDIRLTDSTT
GACFRFFLPL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=33.0434782608696, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=25.7575757575758, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=26.4069264069264, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788393, Length=237, Percent_Identity=28.2700421940928, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=321, Percent_Identity=24.6105919003115, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=27.9835390946502, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=24.3697478991597, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788279, Length=314, Percent_Identity=22.6114649681529, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790861, Length=428, Percent_Identity=21.7289719626168, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=25.8620689655172, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081816, Length=334, Percent_Identity=24.8502994011976, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=24.3478260869565, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=264, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=27.2388059701493, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787894, Length=263, Percent_Identity=30.4182509505703, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790551, Length=289, Percent_Identity=23.8754325259516, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55445; Mature: 55445

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCSLTLSQRLSLVFTVVLLFCAAVTCGVHIYSSNLYGNAMVQRLSAGLAQQIVITESLL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
DNRGQVNHRTLKSLFERLMTLNPSVELYIVSPEGRLLVEAAPPGHIKRRYINIAPLKKFL
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCHHHHHHHH
SGAVWPVYGDDPRSVNKKKVFSTAPLYLRDDLKGYLYIILQGEELNALTDAAWTKALWNA
CCCCCEEECCCCCCCCHHHHHCCCCCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHH
LYWSLFLVVICGLLSGMLVWYWVTRPIQQLTENVSGIEQDSISAIKQLAIQRPATPPSNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCH
VEILHNAFIELARKISCQWDQLSESDQQRREFIANISHDLRTPLTSLLGYLETLSMKSDS
HHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSSEDCHKYLTTALRQGHKVRHLSCQLFELARLEHGAIKPQLEQFSVCELIQDVAQKFEL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
SIETRRLQLRIMMSHSLPLIRADISMIERVITNLLDNAVRHTPPEGSIRLKVWQEDNRLH
CHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEE
VEVADSGPGLTEDMRTHLFRRASVLCHEPSEEPRGGLGLLIVRRMLVLHGGDIRLTDSTT
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCC
GACFRFFLPL
HHHHHHCCCC
>Mature Secondary Structure
MNCSLTLSQRLSLVFTVVLLFCAAVTCGVHIYSSNLYGNAMVQRLSAGLAQQIVITESLL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
DNRGQVNHRTLKSLFERLMTLNPSVELYIVSPEGRLLVEAAPPGHIKRRYINIAPLKKFL
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCHHHHHHCCHHHHHHHH
SGAVWPVYGDDPRSVNKKKVFSTAPLYLRDDLKGYLYIILQGEELNALTDAAWTKALWNA
CCCCCEEECCCCCCCCHHHHHCCCCCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHH
LYWSLFLVVICGLLSGMLVWYWVTRPIQQLTENVSGIEQDSISAIKQLAIQRPATPPSNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCH
VEILHNAFIELARKISCQWDQLSESDQQRREFIANISHDLRTPLTSLLGYLETLSMKSDS
HHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSSEDCHKYLTTALRQGHKVRHLSCQLFELARLEHGAIKPQLEQFSVCELIQDVAQKFEL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
SIETRRLQLRIMMSHSLPLIRADISMIERVITNLLDNAVRHTPPEGSIRLKVWQEDNRLH
CHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEE
VEVADSGPGLTEDMRTHLFRRASVLCHEPSEEPRGGLGLLIVRRMLVLHGGDIRLTDSTT
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCC
GACFRFFLPL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]