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The map label for this gene is emrK [H]

Identifier: 91210632

GI number: 91210632

Start: 1520401

End: 1521429

Strand: Direct

Name: emrK [H]

Synonym: UTI89_C1609

Alternate gene names: 91210632

Gene position: 1520401-1521429 (Clockwise)

Preceding gene: 91210626

Following gene: 91210633

Centisome position: 30.01

GC content: 46.26

Gene sequence:

>1029_bases
ATGATAATTTCTAAAAAACAGCTTATTGGGGTGGTAGCGATCGGTATTCTTTTGGCTGGCGTTGTCTTTTTTATCTGGTG
GGTAAGCAAAGGAAGATTTATACAGACGACGGATGATGCTTACATAGGTGGTAATATCACCACGGTGGCAAGTAAAGTTT
CTGGTTATATTTCTGCTATAGAGGTGCGCGATAATCAGAGTGTAAAAAAAGGCGATATTATCCTGCGTCTCGATGATCGG
GATTATCGTGCAAATGTCGCCAGGCTTGAGGCAAAAATAAAAAGTAGCAAAGCCAATCTCGAAAGCATTCAAGCCACTAT
TGCGATGCAGCAGTCGATAATTCAAAGTGCCAGTGAAACATGGCAGGCAGTAAAACATGAGGAGCAAAAGCGCCTGCGAG
ATACTGAACGTTATGAAAAACTCGCACAATCAGCGGCAATATCGCAACAAATTATTGATAACGCCAGGTTTGACTACCAG
CAGGTCGCAGCAAAGGAGCGCAAAGCCGCGAACGATTTCCTGGTGGAGAAGCAACGGCTGGCAGTTTTATCTGCTCAGGA
AGAAAACGTACGTGCAAGTATCGAAGAAGTTCAGGCCGCTTTGACTCAGGCACTACTGGATCTGGAATATACCCTTGTTC
GTGCGCCGATTGATGGCATTGTCGCAAACCGCAGCGCCCATACAGGCAGTTGGGTGGAAGGCGGCACATCGTTAGTTTCA
CTAGTACCAGTCAGTGAGTTGTGGGTTGATGCAAATTATAAAGAAAACCAAATAGCGGGAATGAAGCCAGGAATGAAGGC
TGAGATCCGTGCTGATATTCTCAAAGGGGAAGTGTTTCACGGTCACATTGAAAGCCTTTCCCCAGCGACAGGAGCCAGTT
TCAGCTTGATTCCGATAGAAAATGCCACTGGCAATTTCACCAAAATTGTTCAGCGTGTCCCGGTACGGATTGCATTTGAC
GACGCAAAGGAATTAAAGCAACTTCTTCGCCCGGGACTGTCCGTCACCGTCAGTGTTGATGAGAGATGA

Upstream 100 bases:

>100_bases
TCATTTACAGTAGATATTTTGTCAGAAATCATCAAATAAGCCATGTTAAATTTTAAATATGACGTATGCAAGTTTCCGGA
TATATACGGTGTAAAGAGTG

Downstream 100 bases:

>100_bases
TGTCTATGCGTAAACATATTGCTTTCGCCAGTATGTGTATTGGATTATTTATTGCTCAGCTTGATATTCAAATTGTATCG
TCATCCCTAAATGAAATAGG

Product: putative secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDDR
DYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLVS
LVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFD
DAKELKQLLRPGLSVTVSVDER

Sequences:

>Translated_342_residues
MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDDR
DYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLVS
LVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFD
DAKELKQLLRPGLSVTVSVDER
>Mature_342_residues
MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDDR
DYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLVS
LVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFD
DAKELKQLLRPGLSVTVSVDER

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=341, Percent_Identity=31.0850439882698, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789041, Length=334, Percent_Identity=31.1377245508982, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790519, Length=325, Percent_Identity=27.0769230769231, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790024, Length=293, Percent_Identity=25.938566552901, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789637, Length=345, Percent_Identity=27.2463768115942, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1790012, Length=243, Percent_Identity=27.1604938271605, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081951, Length=317, Percent_Identity=27.1293375394322, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37718; Mature: 37718

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHHHHHHEEEE
EVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASET
EECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
WQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQQVAAKERKAANDFLVEKQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLVS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHEE
LVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIE
EEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCHHHHCCCCCCCCEEEEEEC
NATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER
CCCCHHHHHHHHCCCEEEECCHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHHHHHHEEEE
EVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASET
EECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
WQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQQVAAKERKAANDFLVEKQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLVS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHEE
LVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIE
EEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCHHHHCCCCCCCCEEEEEEC
NATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER
CCCCHHHHHHHHCCCEEEECCHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]