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The map label for this gene is atoS [H]

Identifier: 89898657

GI number: 89898657

Start: 998326

End: 999378

Strand: Direct

Name: atoS [H]

Synonym: CF0850

Alternate gene names: 89898657

Gene position: 998326-999378 (Clockwise)

Preceding gene: 89898656

Following gene: 89898659

Centisome position: 85.6

GC content: 41.03

Gene sequence:

>1053_bases
ATGAGAAGCAACGATTGTAAGTCATGTTCTTCGACTCAGGAACTAATAGAGATAAAATCTCGCATCACGCAATCGTATAA
AGAAGCGGATACCATTCTTACAGCAATTCCCGACGGGATTATTCTGCTTTCAGAAATGGGCAATGTCCTTATTTGCAATT
CACAAGCACGCGAAATCTTGGGCATTCCTGAAGGATTAGAAATGCTGCATAAGCCCTTCACAGATTTTTTCCCCGAAACC
TTCTTTGGATTTTCTATAAATGAAGCTCTGAAATCTCTACCTTCTCCGAAAACACTGCGTTTAACCTTATCGAAAAACGA
CCAAGAGCGAGATGCAGAGATATTTGTCAGAAGAAACGCATTAAACGGGTACCTGTTCTTACTCATTCGAGATCGCTCGG
AGTACAAACAGCTAGAAAACGCTATAGAACGTTACAAAAATATCGCCGAACTAGGGAAAATGACAGCTACTCTAGCTCAT
GAAATTCGCAATCCCCTAAGCGGAATTGCCGGATTTGCATCTCTATTAAAGGAAGAACTCCCCTCTTCACGTCATCAACG
TATGCTATCCTCGATCATTGATGGAACACGCTCTCTCAATACACTAGTTTCATCCATGTTAGAGTACACGAAATCTCAAC
CGTTAAATTTAAAAGCTGTAGACTTGCAAGAATTTTTCTCATCACTAATTCCCCTATTATCGATTACATTCCCCTTTTGC
AAATTTGAACGTGAAACCACAGCATCTATAGTACGGTCTATAGATCCTGATAGAATGAATAGTGTGGTGTGGAATCTTGT
AAAAAATGCTGCAGAAGCGACAGAATCCCCTATGACACTAACGCTGCATACATCGGGAGATATCTCAGTAACCAATCCCG
GACAACTGTCTCAAGACGTTTTTGACAAACTGTTCATCCCGTTTTTTACAACAAAAGCTCAGGGGAATGGCTTGGGCCTG
GCAGAAGCTTTAAAAATTATGCGTTTGCATGGAGGTGACATTCGCGTAGACAATGCTAATGCGAAAGTCACCTTCACTTT
AAAACTTCCCTAA

Upstream 100 bases:

>100_bases
GATATTCAAGAAGAACTCTCAGAAATTCGAGAAATCATTACGAAAATTCTTGATACAGACAAACTCAACTATCTGCAAAG
AAAAAAAGAGTTAGGGATTT

Downstream 100 bases:

>100_bases
TCCTAAACTAGAGATTTAAATATCTTTTGGAGGTATCCATGAACCGGCTTGATACTTTTGGGTCCACCCTCCTGTATAAA
CCTGGGTGGTTGTCCTTACT

Product: nitrogen regulation two-component sensor histidine kinase ntrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRSNDCKSCSSTQELIEIKSRITQSYKEADTILTAIPDGIILLSEMGNVLICNSQAREILGIPEGLEMLHKPFTDFFPET
FFGFSINEALKSLPSPKTLRLTLSKNDQERDAEIFVRRNALNGYLFLLIRDRSEYKQLENAIERYKNIAELGKMTATLAH
EIRNPLSGIAGFASLLKEELPSSRHQRMLSSIIDGTRSLNTLVSSMLEYTKSQPLNLKAVDLQEFFSSLIPLLSITFPFC
KFERETTASIVRSIDPDRMNSVVWNLVKNAAEATESPMTLTLHTSGDISVTNPGQLSQDVFDKLFIPFFTTKAQGNGLGL
AEALKIMRLHGGDIRVDNANAKVTFTLKLP

Sequences:

>Translated_350_residues
MRSNDCKSCSSTQELIEIKSRITQSYKEADTILTAIPDGIILLSEMGNVLICNSQAREILGIPEGLEMLHKPFTDFFPET
FFGFSINEALKSLPSPKTLRLTLSKNDQERDAEIFVRRNALNGYLFLLIRDRSEYKQLENAIERYKNIAELGKMTATLAH
EIRNPLSGIAGFASLLKEELPSSRHQRMLSSIIDGTRSLNTLVSSMLEYTKSQPLNLKAVDLQEFFSSLIPLLSITFPFC
KFERETTASIVRSIDPDRMNSVVWNLVKNAAEATESPMTLTLHTSGDISVTNPGQLSQDVFDKLFIPFFTTKAQGNGLGL
AEALKIMRLHGGDIRVDNANAKVTFTLKLP
>Mature_350_residues
MRSNDCKSCSSTQELIEIKSRITQSYKEADTILTAIPDGIILLSEMGNVLICNSQAREILGIPEGLEMLHKPFTDFFPET
FFGFSINEALKSLPSPKTLRLTLSKNDQERDAEIFVRRNALNGYLFLLIRDRSEYKQLENAIERYKNIAELGKMTATLAH
EIRNPLSGIAGFASLLKEELPSSRHQRMLSSIIDGTRSLNTLVSSMLEYTKSQPLNLKAVDLQEFFSSLIPLLSITFPFC
KFERETTASIVRSIDPDRMNSVVWNLVKNAAEATESPMTLTLHTSGDISVTNPGQLSQDVFDKLFIPFFTTKAQGNGLGL
AEALKIMRLHGGDIRVDNANAKVTFTLKLP

Specific function: Member of the two-component regulatory system zraS/zraR. May function as a membrane-associated protein kinase that phosphorylates zraR in response to high concentrations of zinc or lead in the medium [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=37.0535714285714, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788549, Length=337, Percent_Identity=26.1127596439169, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=27.6264591439689, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=23.7960339943343, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=27.4900398406374, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39099; Mature: 39099

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSNDCKSCSSTQELIEIKSRITQSYKEADTILTAIPDGIILLSEMGNVLICNSQAREIL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHCCCCCEEEECCHHHHHH
GIPEGLEMLHKPFTDFFPETFFGFSINEALKSLPSPKTLRLTLSKNDQERDAEIFVRRNA
CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHEEEECC
LNGYLFLLIRDRSEYKQLENAIERYKNIAELGKMTATLAHEIRNPLSGIAGFASLLKEEL
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PSSRHQRMLSSIIDGTRSLNTLVSSMLEYTKSQPLNLKAVDLQEFFSSLIPLLSITFPFC
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
KFERETTASIVRSIDPDRMNSVVWNLVKNAAEATESPMTLTLHTSGDISVTNPGQLSQDV
HCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHH
FDKLFIPFFTTKAQGNGLGLAEALKIMRLHGGDIRVDNANAKVTFTLKLP
HHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEEEECC
>Mature Secondary Structure
MRSNDCKSCSSTQELIEIKSRITQSYKEADTILTAIPDGIILLSEMGNVLICNSQAREIL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHCCCCCEEEECCHHHHHH
GIPEGLEMLHKPFTDFFPETFFGFSINEALKSLPSPKTLRLTLSKNDQERDAEIFVRRNA
CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHEEEECC
LNGYLFLLIRDRSEYKQLENAIERYKNIAELGKMTATLAHEIRNPLSGIAGFASLLKEEL
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PSSRHQRMLSSIIDGTRSLNTLVSSMLEYTKSQPLNLKAVDLQEFFSSLIPLLSITFPFC
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
KFERETTASIVRSIDPDRMNSVVWNLVKNAAEATESPMTLTLHTSGDISVTNPGQLSQDV
HCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHH
FDKLFIPFFTTKAQGNGLGLAEALKIMRLHGGDIRVDNANAKVTFTLKLP
HHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 2666400; 11243806 [H]