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The map label for this gene is atoC [H]

Identifier: 89898659

GI number: 89898659

Start: 1002617

End: 1003777

Strand: Direct

Name: atoC [H]

Synonym: CF0852

Alternate gene names: 89898659

Gene position: 1002617-1003777 (Clockwise)

Preceding gene: 89898657

Following gene: 89898660

Centisome position: 85.97

GC content: 44.62

Gene sequence:

>1161_bases
ATGACCATAGAAAAAGTTCTGATCGTGGACGATGAGCCCCTACTTAGAGATTTTCTTTCTGAACTTCTTTTGTCTCGAGG
ATTCTCTCCGTTTACGGCCGACAATGTTAAGATAGGCTGCCACAAGATCAAGACTGAAAAATACGATCTGATTATCTCGG
ATATGAACATGCCTGATGGAACTGGGATCGACATTATCAAAGCAGCTAGGGAACACTCTCCTCTGACTCCGGTCCTAGTG
ATCACCGCCTACGGGACCATAGAGAATGCCGTAAAAGCAATGTATCACGGAGCTTTTAACTATCTGACTAAACCCTTCTC
CTCAGAAGCTCTTTTTGCCTTCATTGCCAAAGCCGAAGAACTACAAAATTTGGTCAATGAGAACCTTTTACTAAAATCGC
AAATTTCTTCAGAATCCCACCCTCTAATCGCAGAAAGCCCCGCAATGAAGGATTTACTGTCTAAAGCAAGAAAAGCTGCT
GACAGCGCGGCAAACATCTTTATTCATGGAGAATCTGGGTGCGGGAAAGAAGTTCTTTCCTTTTTCATTCATAGGAATTC
CCCCAGGGCTTCCCAGCCTTACATCAAGGTAAACTGCGCTGCCATCCCGGAAACCCTATTGGAGTCTGAGTTTTTCGGTC
ATGAAAAAGGAGCCTTTACAGGAGCAACAGCGAAAAAAGCCGGGCGTTTTGAACTTGCTCACACGGGGACTCTTTTACTA
GATGAAATTACCGAGGTTCCTATACACCTTCAAGCCAAGCTACTCAGAGCAATTCAAGAGAAAGAGTTCGAACATCTAGG
AGGCACTAAAACTCTGTCGGTAGATGTACGCATTCTGGCCACATCAAACCGCGATCTCAAAGAAGCTGTGAGTCAGAAAA
TCTTCCGTCAAGATTTATTCTACCGTCTTAATGTTATCCCTCTCTATCTTCCTCCTTTAAGAGAGAGGAAGGAAGATATT
CTTCCCCTCTCTCAATACTTCTTAGAAAAGTTTTGTAGATTAAACAACAGGCCGATAAAAACACTTTCGGCAAGTGCCAA
AGCCGCGCTGCTGGATTACTCCTGGCCGGGGAACATCCGCGAGCTCTCAAACGTATTAGAGAGGGTAGTGATCTTAGAAA
GCCCCACACATCTTACAGACACCATGCTTGCCCTATGCTAA

Upstream 100 bases:

>100_bases
AAAGAATTGAAAGAAAATTAAGACTAATTAAATCCTATTTACACAGATTAATAACATTTAGTAATAAGAAATCTTAACTT
AAAAAACTAATTACAGCCCA

Downstream 100 bases:

>100_bases
GTATGGATAAACTCAATACCAGGGAGTTTTTCTTGAGTTTCAGAAAATCTTCTGCTAAGCTATCCATCCTCCAAGGTCTC
CAATCTCGCGGGAGAAGGAT

Product: nitrogen regulation two-component transcription regulatory protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTIEKVLIVDDEPLLRDFLSELLLSRGFSPFTADNVKIGCHKIKTEKYDLIISDMNMPDGTGIDIIKAAREHSPLTPVLV
ITAYGTIENAVKAMYHGAFNYLTKPFSSEALFAFIAKAEELQNLVNENLLLKSQISSESHPLIAESPAMKDLLSKARKAA
DSAANIFIHGESGCGKEVLSFFIHRNSPRASQPYIKVNCAAIPETLLESEFFGHEKGAFTGATAKKAGRFELAHTGTLLL
DEITEVPIHLQAKLLRAIQEKEFEHLGGTKTLSVDVRILATSNRDLKEAVSQKIFRQDLFYRLNVIPLYLPPLRERKEDI
LPLSQYFLEKFCRLNNRPIKTLSASAKAALLDYSWPGNIRELSNVLERVVILESPTHLTDTMLALC

Sequences:

>Translated_386_residues
MTIEKVLIVDDEPLLRDFLSELLLSRGFSPFTADNVKIGCHKIKTEKYDLIISDMNMPDGTGIDIIKAAREHSPLTPVLV
ITAYGTIENAVKAMYHGAFNYLTKPFSSEALFAFIAKAEELQNLVNENLLLKSQISSESHPLIAESPAMKDLLSKARKAA
DSAANIFIHGESGCGKEVLSFFIHRNSPRASQPYIKVNCAAIPETLLESEFFGHEKGAFTGATAKKAGRFELAHTGTLLL
DEITEVPIHLQAKLLRAIQEKEFEHLGGTKTLSVDVRILATSNRDLKEAVSQKIFRQDLFYRLNVIPLYLPPLRERKEDI
LPLSQYFLEKFCRLNNRPIKTLSASAKAALLDYSWPGNIRELSNVLERVVILESPTHLTDTMLALC
>Mature_385_residues
TIEKVLIVDDEPLLRDFLSELLLSRGFSPFTADNVKIGCHKIKTEKYDLIISDMNMPDGTGIDIIKAAREHSPLTPVLVI
TAYGTIENAVKAMYHGAFNYLTKPFSSEALFAFIAKAEELQNLVNENLLLKSQISSESHPLIAESPAMKDLLSKARKAAD
SAANIFIHGESGCGKEVLSFFIHRNSPRASQPYIKVNCAAIPETLLESEFFGHEKGAFTGATAKKAGRFELAHTGTLLLD
EITEVPIHLQAKLLRAIQEKEFEHLGGTKTLSVDVRILATSNRDLKEAVSQKIFRQDLFYRLNVIPLYLPPLRERKEDIL
PLSQYFLEKFCRLNNRPIKTLSASAKAALLDYSWPGNIRELSNVLERVVILESPTHLTDTMLALC

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=374, Percent_Identity=48.9304812834225, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1790437, Length=381, Percent_Identity=40.1574803149606, Blast_Score=307, Evalue=9e-85,
Organism=Escherichia coli, GI1788905, Length=378, Percent_Identity=39.9470899470899, Blast_Score=290, Evalue=8e-80,
Organism=Escherichia coli, GI1790299, Length=367, Percent_Identity=38.9645776566758, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI87082117, Length=253, Percent_Identity=51.3833992094862, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI1789087, Length=254, Percent_Identity=48.8188976377953, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI87082152, Length=243, Percent_Identity=48.1481481481481, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1789233, Length=243, Percent_Identity=46.0905349794239, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1786524, Length=247, Percent_Identity=44.5344129554656, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787583, Length=260, Percent_Identity=39.6153846153846, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI87081872, Length=230, Percent_Identity=44.3478260869565, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1789828, Length=272, Percent_Identity=33.8235294117647, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081858, Length=261, Percent_Identity=32.9501915708812, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=109, Percent_Identity=43.1192660550459, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786911, Length=102, Percent_Identity=40.1960784313725, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=34.5132743362832, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787375, Length=133, Percent_Identity=30.8270676691729, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=33.6363636363636, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789402, Length=122, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790552, Length=111, Percent_Identity=29.7297297297297, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 43078; Mature: 42947

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEKVLIVDDEPLLRDFLSELLLSRGFSPFTADNVKIGCHKIKTEKYDLIISDMNMPDG
CCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCC
TGIDIIKAAREHSPLTPVLVITAYGTIENAVKAMYHGAFNYLTKPFSSEALFAFIAKAEE
CCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQNLVNENLLLKSQISSESHPLIAESPAMKDLLSKARKAADSAANIFIHGESGCGKEVLS
HHHHHCCCEEEHHHCCCCCCCCEECCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
FFIHRNSPRASQPYIKVNCAAIPETLLESEFFGHEKGAFTGATAKKAGRFELAHTGTLLL
HHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEEECCCHHHH
DEITEVPIHLQAKLLRAIQEKEFEHLGGTKTLSVDVRILATSNRDLKEAVSQKIFRQDLF
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
YRLNVIPLYLPPLRERKEDILPLSQYFLEKFCRLNNRPIKTLSASAKAALLDYSWPGNIR
HHEEEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCHH
ELSNVLERVVILESPTHLTDTMLALC
HHHHHHHHHHHCCCCCHHHHHHHHHC
>Mature Secondary Structure 
TIEKVLIVDDEPLLRDFLSELLLSRGFSPFTADNVKIGCHKIKTEKYDLIISDMNMPDG
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCC
TGIDIIKAAREHSPLTPVLVITAYGTIENAVKAMYHGAFNYLTKPFSSEALFAFIAKAEE
CCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQNLVNENLLLKSQISSESHPLIAESPAMKDLLSKARKAADSAANIFIHGESGCGKEVLS
HHHHHCCCEEEHHHCCCCCCCCEECCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
FFIHRNSPRASQPYIKVNCAAIPETLLESEFFGHEKGAFTGATAKKAGRFELAHTGTLLL
HHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEEECCCHHHH
DEITEVPIHLQAKLLRAIQEKEFEHLGGTKTLSVDVRILATSNRDLKEAVSQKIFRQDLF
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHH
YRLNVIPLYLPPLRERKEDILPLSQYFLEKFCRLNNRPIKTLSASAKAALLDYSWPGNIR
HHEEEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCHH
ELSNVLERVVILESPTHLTDTMLALC
HHHHHHHHHHHCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]