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The map label for this gene is atsA

Identifier: 89898493

GI number: 89898493

Start: 792262

End: 793182

Strand: Direct

Name: atsA

Synonym: CF0686

Alternate gene names: 89898493

Gene position: 792262-793182 (Clockwise)

Preceding gene: 89898492

Following gene: 89898494

Centisome position: 67.93

GC content: 41.37

Gene sequence:

>921_bases
ATGAGCTGTAGAGAATTAATTGTTTTGGGTTGTTCCAGTCAACAGCCTACGAGAACACGCAACCAAGGGGCTTACCTATT
TCGATGGAATAACGAAGGCTTGCTTTTTGATCCCGGAGAGGGAACTCAAAGACAATTCATTTTCGCTAATATTGCTCCTA
CCGTAGTCTCCAGAATCTTTATTAGCCATTTTCACGGAGATCATTGCCTAGGTTTAGGCTCTATGCTTATGAGGTTGAAC
TTAGATAAGGTTACTCACCCCATACATTGCTACTATCCAGCTTCAGGGAAAAAGTACTTTGATAGGCTACGCTATGGCAC
TATTTACCATGAAACAATTCATGTTATCGAGCATCCTATAGATCGAGAAGGTATTGTTGAGGATTTTGGAAGTTTTCGTA
TCGAAGCGCGTAGGCTCGACCATCTTGTTGATACTTTAGGATGGAGAATTACCGAACCCGACACTATAAAATTCATTCCA
GAGAAAATTAAAGCCTGTGGACTACGTGGACCCATCATGCAAGATCTCCTTCGTGACAAGCAGATAACGATAAACGGAAA
AACTCTATACCTTAAAGATCTAAGCTATGTGAGAAAAGGAGATAGCGTTGCTGTAATTTCTGATTCCCTTCCCTGTCAAT
CGGTTATAGATTTAGCTAGAGACGCCAGAATAATGTTGTGTGAGAGCACATATCTTGAAGAGCATCGCCATTTGGCAAAG
AGCCACTACCATATGACAGCAAAGCAAGCAGCCACACAAGCTTTAGCTGCAGGTGCTCAACAGCTTGTGCTGACACACTT
TTCCGCTCGCTATTTAAATTCTAGAGAGTTTGAATTAGAAGCGAAGGAAATTTTCCCAAATGTGTTTGCAGCTGAAGAAT
TTCGTAGCTACTCCTTCCCTAAAAATCCTCCTTCTAAATAA

Upstream 100 bases:

>100_bases
AAAATTCACAATACTTGGCAGTAAGTTCTAGTAGAGTATTTTTAGTAGATTGGTTTATTCTATTTTTTTGTTTTTCCCAT
AAAAGCTTTCTTCTAAATTT

Downstream 100 bases:

>100_bases
ATCTCTATAAGGAGATACTCTAGAAAAGTACTCAGGAACACCATGGTCTCAGCTTTTTATGCTTTTCTAGATTACCTAAA
AAACATAAAAGCAGCGTCTC

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSCRELIVLGCSSQQPTRTRNQGAYLFRWNNEGLLFDPGEGTQRQFIFANIAPTVVSRIFISHFHGDHCLGLGSMLMRLN
LDKVTHPIHCYYPASGKKYFDRLRYGTIYHETIHVIEHPIDREGIVEDFGSFRIEARRLDHLVDTLGWRITEPDTIKFIP
EKIKACGLRGPIMQDLLRDKQITINGKTLYLKDLSYVRKGDSVAVISDSLPCQSVIDLARDARIMLCESTYLEEHRHLAK
SHYHMTAKQAATQALAAGAQQLVLTHFSARYLNSREFELEAKEIFPNVFAAEEFRSYSFPKNPPSK

Sequences:

>Translated_306_residues
MSCRELIVLGCSSQQPTRTRNQGAYLFRWNNEGLLFDPGEGTQRQFIFANIAPTVVSRIFISHFHGDHCLGLGSMLMRLN
LDKVTHPIHCYYPASGKKYFDRLRYGTIYHETIHVIEHPIDREGIVEDFGSFRIEARRLDHLVDTLGWRITEPDTIKFIP
EKIKACGLRGPIMQDLLRDKQITINGKTLYLKDLSYVRKGDSVAVISDSLPCQSVIDLARDARIMLCESTYLEEHRHLAK
SHYHMTAKQAATQALAAGAQQLVLTHFSARYLNSREFELEAKEIFPNVFAAEEFRSYSFPKNPPSK
>Mature_305_residues
SCRELIVLGCSSQQPTRTRNQGAYLFRWNNEGLLFDPGEGTQRQFIFANIAPTVVSRIFISHFHGDHCLGLGSMLMRLNL
DKVTHPIHCYYPASGKKYFDRLRYGTIYHETIHVIEHPIDREGIVEDFGSFRIEARRLDHLVDTLGWRITEPDTIKFIPE
KIKACGLRGPIMQDLLRDKQITINGKTLYLKDLSYVRKGDSVAVISDSLPCQSVIDLARDARIMLCESTYLEEHRHLAKS
HYHMTAKQAATQALAAGAQQLVLTHFSARYLNSREFELEAKEIFPNVFAAEEFRSYSFPKNPPSK

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI260166619, Length=278, Percent_Identity=25.5395683453237, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI145553959, Length=278, Percent_Identity=25.5395683453237, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI260166622, Length=278, Percent_Identity=25.5395683453237, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87082078, Length=306, Percent_Identity=33.6601307189542, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71985814, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71985808, Length=298, Percent_Identity=25.1677852348993, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_CHLFF (Q253T0)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515603.1
- ProteinModelPortal:   Q253T0
- SMR:   Q253T0
- STRING:   Q253T0
- GeneID:   3959248
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0686
- eggNOG:   COG1234
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- ProtClustDB:   PRK00055
- BioCyc:   CFEL264202:CF0686-MONOMER
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 35032; Mature: 34900

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCRELIVLGCSSQQPTRTRNQGAYLFRWNNEGLLFDPGEGTQRQFIFANIAPTVVSRIF
CCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCEEEEECHHHHHHHHHH
ISHFHGDHCLGLGSMLMRLNLDKVTHPIHCYYPASGKKYFDRLRYGTIYHETIHVIEHPI
HHHCCCCHHHHHHHHHHHHCHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCC
DREGIVEDFGSFRIEARRLDHLVDTLGWRITEPDTIKFIPEKIKACGLRGPIMQDLLRDK
CCCHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCC
QITINGKTLYLKDLSYVRKGDSVAVISDSLPCQSVIDLARDARIMLCESTYLEEHRHLAK
EEEECCCEEEEECHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
SHYHMTAKQAATQALAAGAQQLVLTHFSARYLNSREFELEAKEIFPNVFAAEEFRSYSFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHCCCCC
KNPPSK
CCCCCC
>Mature Secondary Structure 
SCRELIVLGCSSQQPTRTRNQGAYLFRWNNEGLLFDPGEGTQRQFIFANIAPTVVSRIF
CCCEEEEEECCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCEEEEECHHHHHHHHHH
ISHFHGDHCLGLGSMLMRLNLDKVTHPIHCYYPASGKKYFDRLRYGTIYHETIHVIEHPI
HHHCCCCHHHHHHHHHHHHCHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCC
DREGIVEDFGSFRIEARRLDHLVDTLGWRITEPDTIKFIPEKIKACGLRGPIMQDLLRDK
CCCHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCC
QITINGKTLYLKDLSYVRKGDSVAVISDSLPCQSVIDLARDARIMLCESTYLEEHRHLAK
EEEECCCEEEEECHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
SHYHMTAKQAATQALAAGAQQLVLTHFSARYLNSREFELEAKEIFPNVFAAEEFRSYSFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHCCCCC
KNPPSK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA