Click here to switch to the map view.

The map label for this gene is xerC

Identifier: 89898494

GI number: 89898494

Start: 793225

End: 794163

Strand: Direct

Name: xerC

Synonym: CF0687

Alternate gene names: 89898494

Gene position: 793225-794163 (Clockwise)

Preceding gene: 89898493

Following gene: 89898495

Centisome position: 68.02

GC content: 37.81

Gene sequence:

>939_bases
ATGGTCTCAGCTTTTTATGCTTTTCTAGATTACCTAAAAAACATAAAAGCAGCGTCTCCCCATACTCTAAGGAACTACTG
CATAGATCTAAATAGCTTTAAAGTCTTCTTAGAAAAACATGGAAAACTCTCTCCCTCCATGCCCATTTGTTTATTTTCCA
AAGAAAGACAAGAAACGAATCTTCCCTTCTCTCTATTTACGAAAGATGCTGTACGTCTCTACATACTAGAATTAATGCAG
GAAAACAAAGCGAAACGCACAATAAAACGTCGCCTCTCAGCTATTAAAAGCTTCTCACATTATTGTTTAAAACATCGCAT
CCTACTTGAAGATCCAACAGAGACAATTCACGGCCCCAGATTACCCAAAGAATTGCCCTCACCTATTACCTATGAGCAAG
TAGAAATACTCATGGCAACTCCCGATCTCTCAAAATATACAGGATTACGTGACCGCTGCTTATTAGAATTATTCTACAGT
TCAGGATTGCGTATTAGCGAAATTGTCTCTTTAAACCACTGGGACATCGATTTTAACTCTAACCTCATTCGCATCCGTGG
AAAAGGGAAAAAAGAACGAATTATTCCTATTACTACTCTAGCTGCCCAGTGGCTAAAACAGTACCTAAATCATCCAGAAA
GAGCAGGTGTTGCAAAAGACAGTCAAGCGATTTTTTTAAATTGTTTTGGAACAAGATTAACCACGCGCTCTATTGATAGG
AAATTTCAAAAATATCTTCGTCTTTCGGGTTTATCAGGAAATATTACTCCCCATACAATCCGCCATACAATTGCCACACA
CTGGTTAGAGAACGGTATGGATTTAAAAACTATTCAAGCTCTTCTTGGACATAGTTCTTTAGAAACAACAACAATCTATA
CCCATGTATCTATGAAGCTTAAAAAGCAAACACACAATGAGTCTCATCCACACGGCTAA

Upstream 100 bases:

>100_bases
GTTTGCAGCTGAAGAATTTCGTAGCTACTCCTTCCCTAAAAATCCTCCTTCTAAATAAATCTCTATAAGGAGATACTCTA
GAAAAGTACTCAGGAACACC

Downstream 100 bases:

>100_bases
ACCTTAGGCAAACCTCTTGTGCTCTAAGATCCTCTTTGTTATGCTGTCTGCTATGAGCATCGTACTTGATAAAATCGGCA
AAACTTTAGGCACACGCGTA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MVSAFYAFLDYLKNIKAASPHTLRNYCIDLNSFKVFLEKHGKLSPSMPICLFSKERQETNLPFSLFTKDAVRLYILELMQ
ENKAKRTIKRRLSAIKSFSHYCLKHRILLEDPTETIHGPRLPKELPSPITYEQVEILMATPDLSKYTGLRDRCLLELFYS
SGLRISEIVSLNHWDIDFNSNLIRIRGKGKKERIIPITTLAAQWLKQYLNHPERAGVAKDSQAIFLNCFGTRLTTRSIDR
KFQKYLRLSGLSGNITPHTIRHTIATHWLENGMDLKTIQALLGHSSLETTTIYTHVSMKLKKQTHNESHPHG

Sequences:

>Translated_312_residues
MVSAFYAFLDYLKNIKAASPHTLRNYCIDLNSFKVFLEKHGKLSPSMPICLFSKERQETNLPFSLFTKDAVRLYILELMQ
ENKAKRTIKRRLSAIKSFSHYCLKHRILLEDPTETIHGPRLPKELPSPITYEQVEILMATPDLSKYTGLRDRCLLELFYS
SGLRISEIVSLNHWDIDFNSNLIRIRGKGKKERIIPITTLAAQWLKQYLNHPERAGVAKDSQAIFLNCFGTRLTTRSIDR
KFQKYLRLSGLSGNITPHTIRHTIATHWLENGMDLKTIQALLGHSSLETTTIYTHVSMKLKKQTHNESHPHG
>Mature_312_residues
MVSAFYAFLDYLKNIKAASPHTLRNYCIDLNSFKVFLEKHGKLSPSMPICLFSKERQETNLPFSLFTKDAVRLYILELMQ
ENKAKRTIKRRLSAIKSFSHYCLKHRILLEDPTETIHGPRLPKELPSPITYEQVEILMATPDLSKYTGLRDRCLLELFYS
SGLRISEIVSLNHWDIDFNSNLIRIRGKGKKERIIPITTLAAQWLKQYLNHPERAGVAKDSQAIFLNCFGTRLTTRSIDR
KFQKYLRLSGLSGNITPHTIRHTIATHWLENGMDLKTIQALLGHSSLETTTIYTHVSMKLKKQTHNESHPHG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=32.2475570032573, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1790244, Length=303, Percent_Identity=30.6930693069307, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790768, Length=171, Percent_Identity=30.4093567251462, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_CHLFF (Q253S9)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515604.1
- ProteinModelPortal:   Q253S9
- SMR:   Q253S9
- STRING:   Q253S9
- GeneID:   3959221
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0687
- eggNOG:   COG0582
- HOGENOM:   HBG727654
- OMA:   PHTLRNY
- ProtClustDB:   PRK00236
- BioCyc:   CFEL264202:CF0687-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 36004; Mature: 36004

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: ACT_SITE 164-164 ACT_SITE 188-188 ACT_SITE 258-258 ACT_SITE 261-261 ACT_SITE 284-284 ACT_SITE 293-293

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSAFYAFLDYLKNIKAASPHTLRNYCIDLNSFKVFLEKHGKLSPSMPICLFSKERQETN
CHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHCC
LPFSLFTKDAVRLYILELMQENKAKRTIKRRLSAIKSFSHYCLKHRILLEDPTETIHGPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHCCCCC
LPKELPSPITYEQVEILMATPDLSKYTGLRDRCLLELFYSSGLRISEIVSLNHWDIDFNS
CCHHCCCCCCHHHEEEEEECCCHHHHCCHHHHHHHHHHHHCCCCHHHEEECCCEEEECCC
NLIRIRGKGKKERIIPITTLAAQWLKQYLNHPERAGVAKDSQAIFLNCFGTRLTTRSIDR
CEEEEECCCCCCEEEHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEECCCHHHHHHHHH
KFQKYLRLSGLSGNITPHTIRHTIATHWLENGMDLKTIQALLGHSSLETTTIYTHVSMKL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEHHHHH
KKQTHNESHPHG
HHHCCCCCCCCC
>Mature Secondary Structure
MVSAFYAFLDYLKNIKAASPHTLRNYCIDLNSFKVFLEKHGKLSPSMPICLFSKERQETN
CHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHCC
LPFSLFTKDAVRLYILELMQENKAKRTIKRRLSAIKSFSHYCLKHRILLEDPTETIHGPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHCCCCC
LPKELPSPITYEQVEILMATPDLSKYTGLRDRCLLELFYSSGLRISEIVSLNHWDIDFNS
CCHHCCCCCCHHHEEEEEECCCHHHHCCHHHHHHHHHHHHCCCCHHHEEECCCEEEECCC
NLIRIRGKGKKERIIPITTLAAQWLKQYLNHPERAGVAKDSQAIFLNCFGTRLTTRSIDR
CEEEEECCCCCCEEEHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEECCCHHHHHHHHH
KFQKYLRLSGLSGNITPHTIRHTIATHWLENGMDLKTIQALLGHSSLETTTIYTHVSMKL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEHHHHH
KKQTHNESHPHG
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA