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The map label for this gene is fabI [H]

Identifier: 89898427

GI number: 89898427

Start: 725452

End: 726351

Strand: Direct

Name: fabI [H]

Synonym: CF0620

Alternate gene names: 89898427

Gene position: 725452-726351 (Clockwise)

Preceding gene: 89898424

Following gene: 89898429

Centisome position: 62.2

GC content: 42.22

Gene sequence:

>900_bases
ATGTTAAAGATCGATTTAACTGGCAAAGTAGCTTTTATAGCAGGGATTGGTGACGACCAAGGCTATGGCTGGGGAATCGC
TAAAGTTCTGGCTGAAGCTGGAGCTACCATCATTGTAGGAACATGGGTACCTATTTATAAAATCTTCTCTCAATCTTGGG
ATTTAGGGAAATTTGATGAGTCAAGAAAGTTATCCGATGGGAGCCTCTTAGAGATTAAGAAAGTCTATCCCATGGATGCA
AGTTTCGATAAACCAGAGGATGTTCCTTCAGACATTGCTGAGAACAAACGTTATAAAGGGATCTCAGGATACACGATTTC
AGAAGTTGTTGAGCAAGTGACTAAGGATTTCGGTCATATTGATATTTTAATCCACTCTCTAGCTAATAGTCCGGAAATTT
CTAAGTCGCTCTTAGAAACCTCACGCAAAGGTTATCTATCAGCATTAAGCACATCGAGCTATTCTCTAGTAAGCCTATTA
GCTCACTTCGGCCCCATTATGAATCCTGGAGGCAGTAGCATTTCATTAACCTATTTAGCTGCTTCACGAGCTGTTCCAGG
CTATGGCGGAGGCATGAGTGCAGCAAAAGCTGCTTTAGAAAGTGATACAAAAATGCTTGCTTGGGAAGCAGGAAGAAAAT
GGGGAATTCGTGTAAACACCATCTCCGCAGGGCCTCTAGCTAGCCGTGCAGGCAAAGCCATCGGATTTATCGAGAAGATG
GTGGATTATTACTTAGATTGGTCCCCTATTCCCGAACCTATGACAACAGAACAAGTCGGAGCTGCTGCTGCATTTTTAGT
TTCTTCATTAGCTAGTGCAATTACCGGAGAAACACTTTATGTAGATCATGGAGCAAATATTATGGGAATTGGCCCTGAAA
TGCTTCCTAAGAACTCTTAA

Upstream 100 bases:

>100_bases
TAGGCTTGTGAGCGCGGAATTGGCAAAGAGTTTCGTAATAATAAAGAAATCTGCTAACCTCCTCTTATTATCAATATGAA
TGTAGACATAGGATTGGCGG

Downstream 100 bases:

>100_bases
TCCTGCGATACTGCTCAACGCCAGCCTCCCATGCCGAAAGTATTCCTAAATCTTTCGCTGGGGAGGCAAGAAAATCTGCT
ATGCCGTGCATATGTTGGGG

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLKIDLTGKVAFIAGIGDDQGYGWGIAKVLAEAGATIIVGTWVPIYKIFSQSWDLGKFDESRKLSDGSLLEIKKVYPMDA
SFDKPEDVPSDIAENKRYKGISGYTISEVVEQVTKDFGHIDILIHSLANSPEISKSLLETSRKGYLSALSTSSYSLVSLL
AHFGPIMNPGGSSISLTYLAASRAVPGYGGGMSAAKAALESDTKMLAWEAGRKWGIRVNTISAGPLASRAGKAIGFIEKM
VDYYLDWSPIPEPMTTEQVGAAAAFLVSSLASAITGETLYVDHGANIMGIGPEMLPKNS

Sequences:

>Translated_299_residues
MLKIDLTGKVAFIAGIGDDQGYGWGIAKVLAEAGATIIVGTWVPIYKIFSQSWDLGKFDESRKLSDGSLLEIKKVYPMDA
SFDKPEDVPSDIAENKRYKGISGYTISEVVEQVTKDFGHIDILIHSLANSPEISKSLLETSRKGYLSALSTSSYSLVSLL
AHFGPIMNPGGSSISLTYLAASRAVPGYGGGMSAAKAALESDTKMLAWEAGRKWGIRVNTISAGPLASRAGKAIGFIEKM
VDYYLDWSPIPEPMTTEQVGAAAAFLVSSLASAITGETLYVDHGANIMGIGPEMLPKNS
>Mature_299_residues
MLKIDLTGKVAFIAGIGDDQGYGWGIAKVLAEAGATIIVGTWVPIYKIFSQSWDLGKFDESRKLSDGSLLEIKKVYPMDA
SFDKPEDVPSDIAENKRYKGISGYTISEVVEQVTKDFGHIDILIHSLANSPEISKSLLETSRKGYLSALSTSSYSLVSLL
AHFGPIMNPGGSSISLTYLAASRAVPGYGGGMSAAKAALESDTKMLAWEAGRKWGIRVNTISAGPLASRAGKAIGFIEKM
VDYYLDWSPIPEPMTTEQVGAAAAFLVSSLASAITGETLYVDHGANIMGIGPEMLPKNS

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=203, Percent_Identity=33.4975369458128, Blast_Score=104, Evalue=5e-24,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 31853; Mature: 31853

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIDLTGKVAFIAGIGDDQGYGWGIAKVLAEAGATIIVGTWVPIYKIFSQSWDLGKFDE
CEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCC
SRKLSDGSLLEIKKVYPMDASFDKPEDVPSDIAENKRYKGISGYTISEVVEQVTKDFGHI
CCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHH
DILIHSLANSPEISKSLLETSRKGYLSALSTSSYSLVSLLAHFGPIMNPGGSSISLTYLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEE
ASRAVPGYGGGMSAAKAALESDTKMLAWEAGRKWGIRVNTISAGPLASRAGKAIGFIEKM
CCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
VDYYLDWSPIPEPMTTEQVGAAAAFLVSSLASAITGETLYVDHGANIMGIGPEMLPKNS
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHCCCCC
>Mature Secondary Structure
MLKIDLTGKVAFIAGIGDDQGYGWGIAKVLAEAGATIIVGTWVPIYKIFSQSWDLGKFDE
CEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCC
SRKLSDGSLLEIKKVYPMDASFDKPEDVPSDIAENKRYKGISGYTISEVVEQVTKDFGHI
CCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHH
DILIHSLANSPEISKSLLETSRKGYLSALSTSSYSLVSLLAHFGPIMNPGGSSISLTYLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEE
ASRAVPGYGGGMSAAKAALESDTKMLAWEAGRKWGIRVNTISAGPLASRAGKAIGFIEKM
CCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
VDYYLDWSPIPEPMTTEQVGAAAAFLVSSLASAITGETLYVDHGANIMGIGPEMLPKNS
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8391534; 11759840 [H]