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The map label for this gene is tlyC2 [C]

Identifier: 89898413

GI number: 89898413

Start: 709960

End: 711174

Strand: Direct

Name: tlyC2 [C]

Synonym: CF0606

Alternate gene names: 89898413

Gene position: 709960-711174 (Clockwise)

Preceding gene: 89898412

Following gene: 89898416

Centisome position: 60.88

GC content: 37.53

Gene sequence:

>1215_bases
ATGACTGATTCTCCTTTCTTTTGGCTTGGGGTTAATTTTCTATGTATTGTCCTTCAGGGATTTTATTCTATGATGGAAAT
GGCATGCGTTTCTTTTAACCGCGTACGTCTGCAATACTATCTAACAAAAGATCATAAGAAAGCTCGCTATATTAACTTCC
TTATTCGTCGTCCTTATCGTCTATTCGGAACGGTGATGCTTGGTGTGAACATAACTCTTCAAGTGGGTTCTGAATCTTCT
AGGAACTGTTATAAAGCTCTAGGTTTCTCTCCAGACTATGCTCCTTTTACGCAAATCTTTCTCGTGGTCATTTTTGCCGA
ACTTCTGCCTTTAACAATATCTCGTAAAATTCCTGAGAGATTAGCTCTTTGGGGCGCTCCTATCTTGTATTACTCTCACT
ATCTCTTTTATCCCTTAATTCAGTTTATAGGCAGCCTCACAGAGGGAATTTACTACCTTTTAAAAATAAAGAAAGAAAAG
CTGAACTCAACATTAAGTCGTGATGAATTCCAAAAGGCCTTAGAAACACATCATGAAGAACAAGATTTTAATGTTATTGC
GACAAATATCTTTTCGTTAAGCGCAACATCTGCAGAGCAAGTATGCCAACCTTTAGATCAGGTTACGATGTTGCCTTCTA
CGGCAAATGTTAAAGATTTACGCCGTAAGATTAAAAGCACTGACATGGAATTTATTCCTGTCTATCATAAAGTGCGTAAA
AATGTGATAGGGATAGCTCTTCCCAAGGATTTTGTGAATAAGAGTCCTGAGGATTCTCTAATTCATAATCTCCATTCTCC
ATGGTTCATTACAGCGAAATCTAAATTGATTCGTATACTAAAAGAATTTCGAGATAACCGCTCTAGCGTTGCTGTTGTCT
TGAATTCTTCTGGAGAACCTATGGGGATCCTCAGTTTAAGCGCGATTTTTAACATCTTATTTAATACATCTAACATCGCT
CAACTAAAACCGAAAACGGTTTCCGTAATAGAAAGAACATTTCCAGGAAATACCCCCCTAAAGGATCTACAAAAAGAACT
GGGAATTGAGCTAACTCGTTATGGGGTAGAAACCTTAGCCCAACTAGTTTTACAGTTGCTAGATACTCCTGCGGAAATTG
GGACTTCTGTAATTACTGATAACCTTCTTTTAGAGGTTAAAGAAGTGTCGTTATACGGGATTAAAAGCGTCTCCATTAAG
AATCTACTTTCATAA

Upstream 100 bases:

>100_bases
ATTCCAATCACAGGAACAAAGCTCATGTGGAAGAATCTTATGTTTCAAGTTTTAGATGCGGCTCCCAATCGCATACGCCG
AGTCTATATAAGGAAAATGC

Downstream 100 bases:

>100_bases
AGTCTACCAAGCACTTTTTAAATGAGTAATTACCTTGACGATTTTTTCTAGGGCTAAATCTAAGTCTTCCTGAGTGAGTA
AATGAGAGAAAGAAAATCGC

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTDSPFFWLGVNFLCIVLQGFYSMMEMACVSFNRVRLQYYLTKDHKKARYINFLIRRPYRLFGTVMLGVNITLQVGSESS
RNCYKALGFSPDYAPFTQIFLVVIFAELLPLTISRKIPERLALWGAPILYYSHYLFYPLIQFIGSLTEGIYYLLKIKKEK
LNSTLSRDEFQKALETHHEEQDFNVIATNIFSLSATSAEQVCQPLDQVTMLPSTANVKDLRRKIKSTDMEFIPVYHKVRK
NVIGIALPKDFVNKSPEDSLIHNLHSPWFITAKSKLIRILKEFRDNRSSVAVVLNSSGEPMGILSLSAIFNILFNTSNIA
QLKPKTVSVIERTFPGNTPLKDLQKELGIELTRYGVETLAQLVLQLLDTPAEIGTSVITDNLLLEVKEVSLYGIKSVSIK
NLLS

Sequences:

>Translated_404_residues
MTDSPFFWLGVNFLCIVLQGFYSMMEMACVSFNRVRLQYYLTKDHKKARYINFLIRRPYRLFGTVMLGVNITLQVGSESS
RNCYKALGFSPDYAPFTQIFLVVIFAELLPLTISRKIPERLALWGAPILYYSHYLFYPLIQFIGSLTEGIYYLLKIKKEK
LNSTLSRDEFQKALETHHEEQDFNVIATNIFSLSATSAEQVCQPLDQVTMLPSTANVKDLRRKIKSTDMEFIPVYHKVRK
NVIGIALPKDFVNKSPEDSLIHNLHSPWFITAKSKLIRILKEFRDNRSSVAVVLNSSGEPMGILSLSAIFNILFNTSNIA
QLKPKTVSVIERTFPGNTPLKDLQKELGIELTRYGVETLAQLVLQLLDTPAEIGTSVITDNLLLEVKEVSLYGIKSVSIK
NLLS
>Mature_403_residues
TDSPFFWLGVNFLCIVLQGFYSMMEMACVSFNRVRLQYYLTKDHKKARYINFLIRRPYRLFGTVMLGVNITLQVGSESSR
NCYKALGFSPDYAPFTQIFLVVIFAELLPLTISRKIPERLALWGAPILYYSHYLFYPLIQFIGSLTEGIYYLLKIKKEKL
NSTLSRDEFQKALETHHEEQDFNVIATNIFSLSATSAEQVCQPLDQVTMLPSTANVKDLRRKIKSTDMEFIPVYHKVRKN
VIGIALPKDFVNKSPEDSLIHNLHSPWFITAKSKLIRILKEFRDNRSSVAVVLNSSGEPMGILSLSAIFNILFNTSNIAQ
LKPKTVSVIERTFPGNTPLKDLQKELGIELTRYGVETLAQLVLQLLDTPAEIGTSVITDNLLLEVKEVSLYGIKSVSIKN
LLS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Escherichia coli, GI145693175, Length=403, Percent_Identity=20.3473945409429, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790664, Length=366, Percent_Identity=20.7650273224044, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 45968; Mature: 45837

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSPFFWLGVNFLCIVLQGFYSMMEMACVSFNRVRLQYYLTKDHKKARYINFLIRRPYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHCCHH
LFGTVMLGVNITLQVGSESSRNCYKALGFSPDYAPFTQIFLVVIFAELLPLTISRKIPER
HHHHHHCCEEEEEEECCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALWGAPILYYSHYLFYPLIQFIGSLTEGIYYLLKIKKEKLNSTLSRDEFQKALETHHEE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
QDFNVIATNIFSLSATSAEQVCQPLDQVTMLPSTANVKDLRRKIKSTDMEFIPVYHKVRK
CCCCEEEHHHHHCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
NVIGIALPKDFVNKSPEDSLIHNLHSPWFITAKSKLIRILKEFRDNRSSVAVVLNSSGEP
CCEEEECCHHHCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCC
MGILSLSAIFNILFNTSNIAQLKPKTVSVIERTFPGNTPLKDLQKELGIELTRYGVETLA
CHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
QLVLQLLDTPAEIGTSVITDNLLLEVKEVSLYGIKSVSIKNLLS
HHHHHHHCCCHHHHHHHHHHHHHHEEHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
TDSPFFWLGVNFLCIVLQGFYSMMEMACVSFNRVRLQYYLTKDHKKARYINFLIRRPYR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHCCHH
LFGTVMLGVNITLQVGSESSRNCYKALGFSPDYAPFTQIFLVVIFAELLPLTISRKIPER
HHHHHHCCEEEEEEECCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALWGAPILYYSHYLFYPLIQFIGSLTEGIYYLLKIKKEKLNSTLSRDEFQKALETHHEE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
QDFNVIATNIFSLSATSAEQVCQPLDQVTMLPSTANVKDLRRKIKSTDMEFIPVYHKVRK
CCCCEEEHHHHHCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
NVIGIALPKDFVNKSPEDSLIHNLHSPWFITAKSKLIRILKEFRDNRSSVAVVLNSSGEP
CCEEEECCHHHCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCC
MGILSLSAIFNILFNTSNIAQLKPKTVSVIERTFPGNTPLKDLQKELGIELTRYGVETLA
CHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
QLVLQLLDTPAEIGTSVITDNLLLEVKEVSLYGIKSVSIKNLLS
HHHHHHHCCCHHHHHHHHHHHHHHEEHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]