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The map label for this gene is kdtA1 [H]

Identifier: 89898199

GI number: 89898199

Start: 465026

End: 466330

Strand: Direct

Name: kdtA1 [H]

Synonym: CF0392

Alternate gene names: 89898199

Gene position: 465026-466330 (Clockwise)

Preceding gene: 89898198

Following gene: 89898216

Centisome position: 39.87

GC content: 39.92

Gene sequence:

>1305_bases
ATGATCAAACGACGACTAACTAAGTTACATACCTTCCTATACGATTGCTTTTTGATCTTGGCGTTTATAGTTGCGCTTCC
TAGGATTCTCTATAAAAGATTGGTTCATGGAAAGTATGCTAAGTCGTTAAAAATTCGTTTTGGATTGGAGAAACCAAAAT
TGCCAGGAAAAGGTCCTGTAGCATGGTTCCACGGTGCTTCCGTGGGAGAGACAGCGCTGTTGGTTCCCTTTATTCAACGA
TTCATGAAAGAGTATCCCGAATGGCGTTTTCTTGTTACATCTTGTACAGAATCTGGATATGAAAATGCTCGCAGATTGTT
TGAACCTATGGGAGTCGCTACTTGCATTTTACCTTTGGATTTAAGCTTAATTATTAAACCAGTTGTCAGAACAATATCAC
CCTCTTTATTAGTTTTTTCTGAAGGGGATTGCTGGTTAAACTTTGTCGAAGAGGCAAAGAGGATTGGGGCTACTGCAGTG
GTGATTAACGGGAAGCTTTCTGCAAATTCTTGTAAGCGGTTTACGATTTTAAAACGTTTTGGCAGAAGCTATTTTTCTCC
TATAGATGGATTTTTACTTCAGGATGACCAGCATAGAGAACGTTTTTTACGTCTTGGCGTTAGTGAAGAGAAAATAGAGG
TTACAGGAAATATTAAAACCTATACAGGAGCCTCCTCTGAAAATAATGAACGGGATTATTGGAGAGAGAAATTACAATTG
TCTCCAAATACGGAATTGCTAGTTTTGGGCTCCACGCATCCTAAAGATGTTGATGCTTGGCTTCCTGTCATTCGCGGGAT
TCACCACAGAAATTTAAAAGTTCTTTGGGTGCCTCGTCATATTGAGAGATCTAAGGAACTTGAAAGCCTTTTAGTTAAAG
AAAATATTTCTTATGGCTTGTGGAGTCGGGGAGCGACTTTCAAGGAGAACGACGCCATTATAGTGGACGCGATTGGCTGG
TTAAAACGGTTGTATTCTGCTGCCGATCTAGCTTTTGTAGGCGGAACTTTTGACGATCGAGTTGGGGGACACAATCTGTT
AGAGCCTCTTCAGTGCGGTGTGCCACTGATGTTTGGTCCCCATATTAAATCTCAATCAGACTTAGCGGTTCGTCTTTTAT
CCATCAAAGCAGGTTGCTGTTTAGATGAAACAACTATGATAGAGGTAGTTTCATTTTTACTTGATCATCCTGAAGAAAGA
GCTGCCTATGTTCAAAAGGGTAAAGAGTTCTTACATGAGGAAAAAGTGGCTTTTGATCGTACTTGGGAATCTTTTAAGAA
ATATATCCCTTGTGTAAAAATATAG

Upstream 100 bases:

>100_bases
AAGTTTTATCTTTAGCACGAGAGGCTGTCTCTAGGTATCTAGAAGATAAAGAAGTGAAGAAGGAAATTTTCGTTCCAAAT
AGATTAGTGAATTTTGTGCT

Downstream 100 bases:

>100_bases
AGATCTGCTAAAGTCTCTTACTTATCGCGGGATAGAGTAGTGGTCATCTCGTTGGGCTCATAACCCAAAGGTCGGAGGTT
CGAATCCTTCTCCCGCTATT

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MIKRRLTKLHTFLYDCFLILAFIVALPRILYKRLVHGKYAKSLKIRFGLEKPKLPGKGPVAWFHGASVGETALLVPFIQR
FMKEYPEWRFLVTSCTESGYENARRLFEPMGVATCILPLDLSLIIKPVVRTISPSLLVFSEGDCWLNFVEEAKRIGATAV
VINGKLSANSCKRFTILKRFGRSYFSPIDGFLLQDDQHRERFLRLGVSEEKIEVTGNIKTYTGASSENNERDYWREKLQL
SPNTELLVLGSTHPKDVDAWLPVIRGIHHRNLKVLWVPRHIERSKELESLLVKENISYGLWSRGATFKENDAIIVDAIGW
LKRLYSAADLAFVGGTFDDRVGGHNLLEPLQCGVPLMFGPHIKSQSDLAVRLLSIKAGCCLDETTMIEVVSFLLDHPEER
AAYVQKGKEFLHEEKVAFDRTWESFKKYIPCVKI

Sequences:

>Translated_434_residues
MIKRRLTKLHTFLYDCFLILAFIVALPRILYKRLVHGKYAKSLKIRFGLEKPKLPGKGPVAWFHGASVGETALLVPFIQR
FMKEYPEWRFLVTSCTESGYENARRLFEPMGVATCILPLDLSLIIKPVVRTISPSLLVFSEGDCWLNFVEEAKRIGATAV
VINGKLSANSCKRFTILKRFGRSYFSPIDGFLLQDDQHRERFLRLGVSEEKIEVTGNIKTYTGASSENNERDYWREKLQL
SPNTELLVLGSTHPKDVDAWLPVIRGIHHRNLKVLWVPRHIERSKELESLLVKENISYGLWSRGATFKENDAIIVDAIGW
LKRLYSAADLAFVGGTFDDRVGGHNLLEPLQCGVPLMFGPHIKSQSDLAVRLLSIKAGCCLDETTMIEVVSFLLDHPEER
AAYVQKGKEFLHEEKVAFDRTWESFKKYIPCVKI
>Mature_434_residues
MIKRRLTKLHTFLYDCFLILAFIVALPRILYKRLVHGKYAKSLKIRFGLEKPKLPGKGPVAWFHGASVGETALLVPFIQR
FMKEYPEWRFLVTSCTESGYENARRLFEPMGVATCILPLDLSLIIKPVVRTISPSLLVFSEGDCWLNFVEEAKRIGATAV
VINGKLSANSCKRFTILKRFGRSYFSPIDGFLLQDDQHRERFLRLGVSEEKIEVTGNIKTYTGASSENNERDYWREKLQL
SPNTELLVLGSTHPKDVDAWLPVIRGIHHRNLKVLWVPRHIERSKELESLLVKENISYGLWSRGATFKENDAIIVDAIGW
LKRLYSAADLAFVGGTFDDRVGGHNLLEPLQCGVPLMFGPHIKSQSDLAVRLLSIKAGCCLDETTMIEVVSFLLDHPEER
AAYVQKGKEFLHEEKVAFDRTWESFKKYIPCVKI

Specific function: Transfers three 3-deoxy-D-mono octulonic acid (KDO) individually from CMP-KDO to a tetraacyldisaccharide 1,4'- bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=428, Percent_Identity=27.803738317757, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 49513; Mature: 49513

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRRLTKLHTFLYDCFLILAFIVALPRILYKRLVHGKYAKSLKIRFGLEKPKLPGKGPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCCE
AWFHGASVGETALLVPFIQRFMKEYPEWRFLVTSCTESGYENARRLFEPMGVATCILPLD
EEECCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LSLIIKPVVRTISPSLLVFSEGDCWLNFVEEAKRIGATAVVINGKLSANSCKRFTILKRF
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
GRSYFSPIDGFLLQDDQHRERFLRLGVSEEKIEVTGNIKTYTGASSENNERDYWREKLQL
HHHHCCCCCCCEECCHHHHHHHHHCCCCCCEEEEEECEEEEECCCCCCCCHHHHHHHHCC
SPNTELLVLGSTHPKDVDAWLPVIRGIHHRNLKVLWVPRHIERSKELESLLVKENISYGL
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCC
WSRGATFKENDAIIVDAIGWLKRLYSAADLAFVGGTFDDRVGGHNLLEPLQCGVPLMFGP
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCCCCEECC
HIKSQSDLAVRLLSIKAGCCLDETTMIEVVSFLLDHPEERAAYVQKGKEFLHEEKVAFDR
CCCCCCHHHHEEEHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TWESFKKYIPCVKI
HHHHHHHHCCCCCC
>Mature Secondary Structure
MIKRRLTKLHTFLYDCFLILAFIVALPRILYKRLVHGKYAKSLKIRFGLEKPKLPGKGPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCCE
AWFHGASVGETALLVPFIQRFMKEYPEWRFLVTSCTESGYENARRLFEPMGVATCILPLD
EEECCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LSLIIKPVVRTISPSLLVFSEGDCWLNFVEEAKRIGATAVVINGKLSANSCKRFTILKRF
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
GRSYFSPIDGFLLQDDQHRERFLRLGVSEEKIEVTGNIKTYTGASSENNERDYWREKLQL
HHHHCCCCCCCEECCHHHHHHHHHCCCCCCEEEEEECEEEEECCCCCCCCHHHHHHHHCC
SPNTELLVLGSTHPKDVDAWLPVIRGIHHRNLKVLWVPRHIERSKELESLLVKENISYGL
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCC
WSRGATFKENDAIIVDAIGWLKRLYSAADLAFVGGTFDDRVGGHNLLEPLQCGVPLMFGP
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCCCCEECC
HIKSQSDLAVRLLSIKAGCCLDETTMIEVVSFLLDHPEERAAYVQKGKEFLHEEKVAFDR
CCCCCCHHHHEEEHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TWESFKKYIPCVKI
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8748024; 10192388; 10684935; 10871362; 9765820 [H]