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The map label for this gene is ispH [H]

Identifier: 89898079

GI number: 89898079

Start: 318711

End: 319640

Strand: Direct

Name: ispH [H]

Synonym: CF0272

Alternate gene names: 89898079

Gene position: 318711-319640 (Clockwise)

Preceding gene: 89898078

Following gene: 89898080

Centisome position: 27.33

GC content: 39.57

Gene sequence:

>930_bases
ATGCGCAGGGTTATATTAAGTAATCCCAGAGGTTTTTGCGCCGGGGTAGTTCGCGCTATCCAAGTAGTAGAGGCTGCTTT
AGAGAAGTGGGGAGCGCCCATTTATGTGAAACATGAAATTGTTCATAACCGTCATGTGGTAGATGATCTCAGAAGACGCG
GGGCTATTTTTATCGAAAACCTGAGTGATATTCCTTGTGGGGGAAAGGTTATCTATTCTGCACACGGCATTCCTCCTGAG
GTTCGTGAAGAGGCAAAAAATCGAAATCTTTTTGATATTGATGCAACCTGTGTGTTGGTAACTAAAATTCATTCTGCGGT
TAAGCTTTATGCAAGTAAGGGTTATCAAATTATTTTGATTGGAAAGAAAAAACATGTGGAAGTTATTGGGATTTATGGAG
AAGCTCCCGATAGTGTTACAGTAGTAGAGAAGGTAGAAGATGTTGAAAATCTACCCTTTGGTATTGATACACCTTTATTT
TTTGTCACCCAAACTACATTGAGTCTGGATGATGTTGCAGAAATTACCCAAGCCTTAAAGGTTCGTTATCCTAATGTTAT
TACGTTACCTAGTTCCTCTGTATGTTATGCTACGCAGAATCGTCAGGAGGCACTACGTTCGGTATTGCCTAGAGTGAATT
TTGTTTATGTTGTTGGAGATGTTCAAAGTTCCAACTCTAACCGTTTACGCGAGGTCGCAGAAAGGAGAAATATACCCGCA
AGGCTAGTGAATAGTCCGGATCATATTTCTGACGAGATTTTAAATTATTCTGGTGATATTGCAATAACAGCAGGAGCATC
TACTCCCGAGAATATAGTTCAACTTTGTATTTCTAGGTTGAAAGAATTAATTCCCGATTTACAAGTTGAAGAAGATATAT
TTGCTATAGAAGATGTCGTATTCCAACCGCCTAAAGAGCTTCGCAACTAA

Upstream 100 bases:

>100_bases
GATAAAAGTCTTCTGTTATATTAATAACCCTTAGAAAAAGTAAAAAATCTTTTTCTAAGGGTTTTTTTAAGCATCACGCT
CAATTCTGGAGGTGAGATGT

Downstream 100 bases:

>100_bases
AAAGTCCTCTTTCCTATATATATTGCGAGTAGTGATTCACAGAATGTGGTTCTCTGTTAGGGAATATGTTTATCTATCCT
GCTCGCTTTATGTTAAGTAC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRRVILSNPRGFCAGVVRAIQVVEAALEKWGAPIYVKHEIVHNRHVVDDLRRRGAIFIENLSDIPCGGKVIYSAHGIPPE
VREEAKNRNLFDIDATCVLVTKIHSAVKLYASKGYQIILIGKKKHVEVIGIYGEAPDSVTVVEKVEDVENLPFGIDTPLF
FVTQTTLSLDDVAEITQALKVRYPNVITLPSSSVCYATQNRQEALRSVLPRVNFVYVVGDVQSSNSNRLREVAERRNIPA
RLVNSPDHISDEILNYSGDIAITAGASTPENIVQLCISRLKELIPDLQVEEDIFAIEDVVFQPPKELRN

Sequences:

>Translated_309_residues
MRRVILSNPRGFCAGVVRAIQVVEAALEKWGAPIYVKHEIVHNRHVVDDLRRRGAIFIENLSDIPCGGKVIYSAHGIPPE
VREEAKNRNLFDIDATCVLVTKIHSAVKLYASKGYQIILIGKKKHVEVIGIYGEAPDSVTVVEKVEDVENLPFGIDTPLF
FVTQTTLSLDDVAEITQALKVRYPNVITLPSSSVCYATQNRQEALRSVLPRVNFVYVVGDVQSSNSNRLREVAERRNIPA
RLVNSPDHISDEILNYSGDIAITAGASTPENIVQLCISRLKELIPDLQVEEDIFAIEDVVFQPPKELRN
>Mature_309_residues
MRRVILSNPRGFCAGVVRAIQVVEAALEKWGAPIYVKHEIVHNRHVVDDLRRRGAIFIENLSDIPCGGKVIYSAHGIPPE
VREEAKNRNLFDIDATCVLVTKIHSAVKLYASKGYQIILIGKKKHVEVIGIYGEAPDSVTVVEKVEDVENLPFGIDTPLF
FVTQTTLSLDDVAEITQALKVRYPNVITLPSSSVCYATQNRQEALRSVLPRVNFVYVVGDVQSSNSNRLREVAERRNIPA
RLVNSPDHISDEILNYSGDIAITAGASTPENIVQLCISRLKELIPDLQVEEDIFAIEDVVFQPPKELRN

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=314, Percent_Identity=46.4968152866242, Blast_Score=267, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34415; Mature: 34415

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVILSNPRGFCAGVVRAIQVVEAALEKWGAPIYVKHEIVHNRHVVDDLRRRGAIFIEN
CCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCHHHHHHHHHCCCEEEEC
LSDIPCGGKVIYSAHGIPPEVREEAKNRNLFDIDATCVLVTKIHSAVKLYASKGYQIILI
CCCCCCCCEEEEECCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEE
GKKKHVEVIGIYGEAPDSVTVVEKVEDVENLPFGIDTPLFFVTQTTLSLDDVAEITQALK
ECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
VRYPNVITLPSSSVCYATQNRQEALRSVLPRVNFVYVVGDVQSSNSNRLREVAERRNIPA
HCCCCEEECCCCCEEEECCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCC
RLVNSPDHISDEILNYSGDIAITAGASTPENIVQLCISRLKELIPDLQVEEDIFAIEDVV
EECCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FQPPKELRN
CCCCHHHCC
>Mature Secondary Structure
MRRVILSNPRGFCAGVVRAIQVVEAALEKWGAPIYVKHEIVHNRHVVDDLRRRGAIFIEN
CCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCHHHHHHHHHCCCEEEEC
LSDIPCGGKVIYSAHGIPPEVREEAKNRNLFDIDATCVLVTKIHSAVKLYASKGYQIILI
CCCCCCCCEEEEECCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEE
GKKKHVEVIGIYGEAPDSVTVVEKVEDVENLPFGIDTPLFFVTQTTLSLDDVAEITQALK
ECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHH
VRYPNVITLPSSSVCYATQNRQEALRSVLPRVNFVYVVGDVQSSNSNRLREVAERRNIPA
HCCCCEEECCCCCEEEECCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCC
RLVNSPDHISDEILNYSGDIAITAGASTPENIVQLCISRLKELIPDLQVEEDIFAIEDVV
EECCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FQPPKELRN
CCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA