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The map label for this gene is adk1 [H]

Identifier: 89898072

GI number: 89898072

Start: 309606

End: 310256

Strand: Direct

Name: adk1 [H]

Synonym: CF0265

Alternate gene names: 89898072

Gene position: 309606-310256 (Clockwise)

Preceding gene: 89898068

Following gene: 89898074

Centisome position: 26.55

GC content: 39.78

Gene sequence:

>651_bases
ATGATCGATGAATCGATAGCTGATAGCTTAAAGCTGTATACTAAACCTTTTTCTTCTATTCTTTTATTCGGTCCTCCAGG
AGCTGGTAAAGATTTATTAGGAGACTTTATAGCTCATGGTGGTAGCCAAGTTTATGTTTCTTTAGGAGACATTTTCCGTT
GTTATCCTATAGGGTCTCCTATCCGACAGCTTTTTCATAAATATGCAGTTTCTGGATCTTTGATACCGGACGAAGATGTC
GTTGCTGTATGGAATTATTATGTTCAAGGATTAATTGCTACAGGGAAGTTTCTTCCTGATCGTCAAGATCTTCTCATTAG
CGGTCTTCCAAGAACAGTAGGCCAGGCGAAACTTCTTGATGCGTATATCACGGTACGTCATGTAATTATTTTAGAAGTAC
ATGAAGAAGCTAAACTACTCGAGCGTACACAACATTCTCTCTATAGCAAGGGAAGAGTTAATGAGGTAGGCATTGAGGTA
TTGCAGAAACGTTTGCAATCGTATCAAAAAGATATTGATGCCATTATTCAGCTCTACCCTTTGCATAAAATTTCGCGCAT
TAGTGCTGAGCAGAAGCCGATGGAAGTCCTTCGAGATGTGCTATCTCGACTTGCTCATGTCTTTTCTCATCCTGGCAAAC
CTGTGAATTAG

Upstream 100 bases:

>100_bases
TGGGGAGAATTTTTATATGCTAGGGCTATTATTTTTCAAGGTAATCGACTAAAGTGCGGGGAAACATACAAACTGGGGTA
GCGCTAGCTAAAATTATTTT

Downstream 100 bases:

>100_bases
ATGGGTATATCTGAGCTAGAGAGAATTCAGAGGTTTTATCTGCAAGGTTTGGATAGCGCTGTGCTATAGACTTTAGTAAA
GTCTTTGTTAGATCTTCACT

Product: adenylate kinase

Products: NA

Alternate protein names: AK; ATP-AMP transphosphorylase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MIDESIADSLKLYTKPFSSILLFGPPGAGKDLLGDFIAHGGSQVYVSLGDIFRCYPIGSPIRQLFHKYAVSGSLIPDEDV
VAVWNYYVQGLIATGKFLPDRQDLLISGLPRTVGQAKLLDAYITVRHVIILEVHEEAKLLERTQHSLYSKGRVNEVGIEV
LQKRLQSYQKDIDAIIQLYPLHKISRISAEQKPMEVLRDVLSRLAHVFSHPGKPVN

Sequences:

>Translated_216_residues
MIDESIADSLKLYTKPFSSILLFGPPGAGKDLLGDFIAHGGSQVYVSLGDIFRCYPIGSPIRQLFHKYAVSGSLIPDEDV
VAVWNYYVQGLIATGKFLPDRQDLLISGLPRTVGQAKLLDAYITVRHVIILEVHEEAKLLERTQHSLYSKGRVNEVGIEV
LQKRLQSYQKDIDAIIQLYPLHKISRISAEQKPMEVLRDVLSRLAHVFSHPGKPVN
>Mature_216_residues
MIDESIADSLKLYTKPFSSILLFGPPGAGKDLLGDFIAHGGSQVYVSLGDIFRCYPIGSPIRQLFHKYAVSGSLIPDEDV
VAVWNYYVQGLIATGKFLPDRQDLLISGLPRTVGQAKLLDAYITVRHVIILEVHEEAKLLERTQHSLYSKGRVNEVGIEV
LQKRLQSYQKDIDAIIQLYPLHKISRISAEQKPMEVLRDVLSRLAHVFSHPGKPVN

Specific function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in the energy metabolism and nucleotide synthesis, is essential for maintenance and cell growth [H]

COG id: COG0563

COG function: function code F; Adenylate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: 1640 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 847 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006259
- InterPro:   IPR000850 [H]

Pfam domain/function: PF00406 ADK [H]

EC number: =2.7.4.3 [H]

Molecular weight: Translated: 24159; Mature: 24159

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDESIADSLKLYTKPFSSILLFGPPGAGKDLLGDFIAHGGSQVYVSLGDIFRCYPIGSP
CCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHCCCCHH
IRQLFHKYAVSGSLIPDEDVVAVWNYYVQGLIATGKFLPDRQDLLISGLPRTVGQAKLLD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHH
AYITVRHVIILEVHEEAKLLERTQHSLYSKGRVNEVGIEVLQKRLQSYQKDIDAIIQLYP
HHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHKISRISAEQKPMEVLRDVLSRLAHVFSHPGKPVN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIDESIADSLKLYTKPFSSILLFGPPGAGKDLLGDFIAHGGSQVYVSLGDIFRCYPIGSP
CCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHCCCCHH
IRQLFHKYAVSGSLIPDEDVVAVWNYYVQGLIATGKFLPDRQDLLISGLPRTVGQAKLLD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHH
AYITVRHVIILEVHEEAKLLERTQHSLYSKGRVNEVGIEVLQKRLQSYQKDIDAIIQLYP
HHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHKISRISAEQKPMEVLRDVLSRLAHVFSHPGKPVN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA