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The map label for this gene is pgsA2 [H]

Identifier: 89897999

GI number: 89897999

Start: 225342

End: 225968

Strand: Direct

Name: pgsA2 [H]

Synonym: CF0192

Alternate gene names: 89897999

Gene position: 225342-225968 (Clockwise)

Preceding gene: 89897997

Following gene: 89898001

Centisome position: 19.32

GC content: 37.16

Gene sequence:

>627_bases
ATGAGGGATGGGGTGGGACTGCCTAATTATCTAACTTTTTCCCGGCTATTTATAACGCCAATTTTCATGTTACTTTACCT
TAAAGGAAAGTGGCTTGGAATTACTCCCGTAGTTCTTCCATATGTTCTACTTGCTCTTTTAGGTCTCTCAGAGCTTACTG
ATGCTATCGATGGCTACATAGCTAGAAAATTTTCTCAAGTTACAGATTTAGGGAAACTTCTTGATCCCATGGCTGATAGC
ATTTATCGGATTTCTCTATATCTGACATTCACTCAACCACCAGTAAATTTACCTCTCATTCTGGTTTTCATTTTCCTGGC
TAGAGATTCTGTAATTAGTACATTACGTACTGTATGTGCTTTTCGAGGAGTCGTTCTTGCTGCTAGAGCGAGTGGGAAAT
TGAAAGCTATTCTACAAGGTATAAGCTTTTTATTAATTTTACTTGCAATGATACCACATTCCCTGGGAATGATTTCTGAA
GGAGATTTAGAACTTTTTGCTTCTGTAGTGGGGTCTATAGTTGCTATTTATTCTGTATGCTCAGGAGTTGAATACTTTTG
GGTGAATAAAAATCATGTATTGCAGAGAGCAAAAATTAAGCCTGGAGATCATAATAGGGAATTATAA

Upstream 100 bases:

>100_bases
ACATTATAACATTCGGTGCTTGCGCTCTAATTCTTATCTATTTAATTTGTCTTTTAGGCATTAGTTTTGTGCTAAGATTC
CTGTTTAAGTAATTTTTTTA

Downstream 100 bases:

>100_bases
ATTTCTAGGTAATGCATAGCCATAGTTGACAGCCCCGAAGATCGAAGCATACCTTCTTCTACAAGTTGAAACCACACATC
GGGTTCGTGTCTGTAGGTAG

Product: CDP-diacylglycerol/glycerol-3-P phosphatydyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MRDGVGLPNYLTFSRLFITPIFMLLYLKGKWLGITPVVLPYVLLALLGLSELTDAIDGYIARKFSQVTDLGKLLDPMADS
IYRISLYLTFTQPPVNLPLILVFIFLARDSVISTLRTVCAFRGVVLAARASGKLKAILQGISFLLILLAMIPHSLGMISE
GDLELFASVVGSIVAIYSVCSGVEYFWVNKNHVLQRAKIKPGDHNREL

Sequences:

>Translated_208_residues
MRDGVGLPNYLTFSRLFITPIFMLLYLKGKWLGITPVVLPYVLLALLGLSELTDAIDGYIARKFSQVTDLGKLLDPMADS
IYRISLYLTFTQPPVNLPLILVFIFLARDSVISTLRTVCAFRGVVLAARASGKLKAILQGISFLLILLAMIPHSLGMISE
GDLELFASVVGSIVAIYSVCSGVEYFWVNKNHVLQRAKIKPGDHNREL
>Mature_208_residues
MRDGVGLPNYLTFSRLFITPIFMLLYLKGKWLGITPVVLPYVLLALLGLSELTDAIDGYIARKFSQVTDLGKLLDPMADS
IYRISLYLTFTQPPVNLPLILVFIFLARDSVISTLRTVCAFRGVVLAARASGKLKAILQGISFLLILLAMIPHSLGMISE
GDLELFASVVGSIVAIYSVCSGVEYFWVNKNHVLQRAKIKPGDHNREL

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23002; Mature: 23002

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDGVGLPNYLTFSRLFITPIFMLLYLKGKWLGITPVVLPYVLLALLGLSELTDAIDGYI
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARKFSQVTDLGKLLDPMADSIYRISLYLTFTQPPVNLPLILVFIFLARDSVISTLRTVCA
HHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FRGVVLAARASGKLKAILQGISFLLILLAMIPHSLGMISEGDLELFASVVGSIVAIYSVC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SGVEYFWVNKNHVLQRAKIKPGDHNREL
CCCEEEEECHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRDGVGLPNYLTFSRLFITPIFMLLYLKGKWLGITPVVLPYVLLALLGLSELTDAIDGYI
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARKFSQVTDLGKLLDPMADSIYRISLYLTFTQPPVNLPLILVFIFLARDSVISTLRTVCA
HHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FRGVVLAARASGKLKAILQGISFLLILLAMIPHSLGMISEGDLELFASVVGSIVAIYSVC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SGVEYFWVNKNHVLQRAKIKPGDHNREL
CCCEEEEECHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]