Click here to switch to the map view.

The map label for this gene is gspD [H]

Identifier: 89897873

GI number: 89897873

Start: 73252

End: 75519

Strand: Direct

Name: gspD [H]

Synonym: CF0066

Alternate gene names: 89897873

Gene position: 73252-75519 (Clockwise)

Preceding gene: 89897872

Following gene: 89897874

Centisome position: 6.28

GC content: 42.64

Gene sequence:

>2268_bases
ATGCGTTTTTTGCGTCATCCTTTAGTTTATTTCTTTGGGTTGTCAAGTTTAGCGTGTTGCACGCCAGGACAGGCCTTAAC
TATTTCAGAAAAAGCCGCCTCCTTGGAAAACTCCAAAGAGTTTATAGACAGTTCTCCAGGCCTAGCCTCGTTTAATGCAG
ATATGAAGGAATATAACCTTCAGCTAAAGAGTTTATATGAAGAGGCCGCAGCTTTGCGTGAGGCGGGATGCGAAGATGAG
GCTCGATGGAAGCTGCTTTTAAGTAAGCTAACGGATGTCAAAAAGCAAATCAAACGCATGGAGGATCTTTGGGCTGCAGA
GATCCGTGAAAGAGGAGAGAACCCTGATGAGTATGCCCTATGGCACCATCCTGAGACTACAATCTATAATCTGGTTTCAG
ATTATGGTGAGGACAACGTCATTTATTTGGTGCCCCAAGATATCGGTTCAATAAAAGTTTCCGCATTATCAAAGTTCACG
GTTCCCAAAGAGGGGTTTGAAGAATGCTTGTTGCAGTTGCTGTCGCGTCTTGGCATTGGCATGCGACAGGTAAGTCCTTG
GATTAAAGAGCTCTATACTACTCATAAAGAAGGTTGCGGTGTTGCAGGCGTTTTTTCTTCTAGGAAGGATTTAGATTTAC
TTCCACCATCCTCTTATATTGGCTATGTGTTAAATTCGAAAAACATTGATGTACGAGCAGATCAACATATCTTAAGAAAA
TTCGCGAATCTCGATACCACGCATATCGATTTATTTGGCGGGAAATTATGGGTGTTTGGTTCTGTCGGAGAGATCAGCGA
ACTTCTGAAAATTTACGACTTTATTCAAGAAGATAGTGTCCGTCAGGAGTATCGTGTCGTCCCTTTAACAAAGATAGAAG
CTTCTGAAATGATCTCTATTCTTAAGGCGGCATTTCGAGAAGATGTAACTAAAGAGGGTGATGAGGAGGGACTAGGTCTT
AAAGTTGTTCCCCTTCAGAATCAGGGGCGTTCTTTATTTTTAAGTGGCACCGCAGCTTTAGTGCGTCAGGCTGTAGATTT
GATTAAAGATCTTGAAGAGGGAATAGAGAATCCCACGGACAAAACTGTCTTCTGGTATAGTGTAAAACACTCAGACCCAC
AAGAATTGGCAGTTTTGTTGTCGCAAGTGCATGATGTCTTTGCTGGTAAAGATGGAGGGGGGGTGCCCTCTTCTTCTGCG
GAATCTATGTTAAGAGATGCGGCCTCTACGATACACATTGACACTTCCTCAGTAGGAGCTACAAAGGAAGGATCTGTAAA
ATACGGGAATTTCATAGCAGATTCTAAAACAGGAACTTTGATCATGGTTGTGGAAAAAGAAGCCCTGCCTAGGATCAAAA
TGTTGTTAAAAAAACTCGACGTTCCTAAAAAGATGGTGCGTATAGAGGTTCTTCTATTTGAAAGAAAGCTTTCTAGCCAG
CGTCAAGCAGGGTTAAATCTTTTGCGACTCGGAGAAGAAGTCTGTAAGAAAACCTCCTCCGCAGTTTCTTGGACAAGCTC
CGGGATTTTAGAATTTTTATTTAAGGGCAGCACAGGATCTTCGTTAGTTCCGAGTTATGATCTTGCCTATCAATTTTTAA
TGGCTCAGGAAGATGTTCGTATTAATGCAAGTCCTTCTGTTGTTACCATGAACCAAACTCCTGCAAGAATTGCTATTGTA
GAGGAGATGTCGATAGCTGTTTCCGCAGATAAGGAAAAGGCTCAGTATAACCGTGCGCAGTACGGTATTATGATCAAAAT
GCTCCCCGTGATCAATGTGGGGGAGGAAGATGGGAAAAGCTACATTACCCTAGAGACGGATATTACCTTCGATACTACAG
GGAAAAATACGAATGAACGTCCTGATGTTACTCGACGTAATATTACTAATAAAGTGCGTATTCCTGATGGAGAAACGGTA
ATTATTGGAGGGTTGCGCTGTAAGCACGCCTCAGATTCTCAAGATGGGATTCCTTTTCTCGGAGAAATTCCCGGAATTGG
GAAGTTATTCGGCATGAATTCTACCTCTGATAGTCAAACGGAGATGTTTGTATTTATCACTCCGAAAATTCTAGATAATC
CCGCTGAGAAAAAAGAGCGCCAAGAAGAGGCAATTCTTTCTTCACGACCCGGAGAAAATGCTGAATTCCGTAAAGCACTA
TGTGCTGGTGAAGAGGCTGCAAAGGCTGCTCATAAAAAATTAGAACTAATTTCCGCTATAGAGCTACCAGCGTCTCAAGT
AGAGGGGCTCGAGTATGATGGGCGGTAA

Upstream 100 bases:

>100_bases
ACAGGGTTTTGATTCTGGATCCGCTGCCGCTAAAGAAGAGGCACATCCAGGGAGACCGCTGCTTGCTGGTAGTGAGGGAA
CCAATAGTGGGGGATCATAA

Downstream 100 bases:

>100_bases
GGCTTTACTATCCCAAGAGCTTCTTAATGCTCTGCCCTATAGCTTTCTAAAAAAGCACTGCTTATTGCCGTTAGAAGAGC
GAGAAGACAGTGTAACCATG

Product: general secretion pathway protein D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MRFLRHPLVYFFGLSSLACCTPGQALTISEKAASLENSKEFIDSSPGLASFNADMKEYNLQLKSLYEEAAALREAGCEDE
ARWKLLLSKLTDVKKQIKRMEDLWAAEIRERGENPDEYALWHHPETTIYNLVSDYGEDNVIYLVPQDIGSIKVSALSKFT
VPKEGFEECLLQLLSRLGIGMRQVSPWIKELYTTHKEGCGVAGVFSSRKDLDLLPPSSYIGYVLNSKNIDVRADQHILRK
FANLDTTHIDLFGGKLWVFGSVGEISELLKIYDFIQEDSVRQEYRVVPLTKIEASEMISILKAAFREDVTKEGDEEGLGL
KVVPLQNQGRSLFLSGTAALVRQAVDLIKDLEEGIENPTDKTVFWYSVKHSDPQELAVLLSQVHDVFAGKDGGGVPSSSA
ESMLRDAASTIHIDTSSVGATKEGSVKYGNFIADSKTGTLIMVVEKEALPRIKMLLKKLDVPKKMVRIEVLLFERKLSSQ
RQAGLNLLRLGEEVCKKTSSAVSWTSSGILEFLFKGSTGSSLVPSYDLAYQFLMAQEDVRINASPSVVTMNQTPARIAIV
EEMSIAVSADKEKAQYNRAQYGIMIKMLPVINVGEEDGKSYITLETDITFDTTGKNTNERPDVTRRNITNKVRIPDGETV
IIGGLRCKHASDSQDGIPFLGEIPGIGKLFGMNSTSDSQTEMFVFITPKILDNPAEKKERQEEAILSSRPGENAEFRKAL
CAGEEAAKAAHKKLELISAIELPASQVEGLEYDGR

Sequences:

>Translated_755_residues
MRFLRHPLVYFFGLSSLACCTPGQALTISEKAASLENSKEFIDSSPGLASFNADMKEYNLQLKSLYEEAAALREAGCEDE
ARWKLLLSKLTDVKKQIKRMEDLWAAEIRERGENPDEYALWHHPETTIYNLVSDYGEDNVIYLVPQDIGSIKVSALSKFT
VPKEGFEECLLQLLSRLGIGMRQVSPWIKELYTTHKEGCGVAGVFSSRKDLDLLPPSSYIGYVLNSKNIDVRADQHILRK
FANLDTTHIDLFGGKLWVFGSVGEISELLKIYDFIQEDSVRQEYRVVPLTKIEASEMISILKAAFREDVTKEGDEEGLGL
KVVPLQNQGRSLFLSGTAALVRQAVDLIKDLEEGIENPTDKTVFWYSVKHSDPQELAVLLSQVHDVFAGKDGGGVPSSSA
ESMLRDAASTIHIDTSSVGATKEGSVKYGNFIADSKTGTLIMVVEKEALPRIKMLLKKLDVPKKMVRIEVLLFERKLSSQ
RQAGLNLLRLGEEVCKKTSSAVSWTSSGILEFLFKGSTGSSLVPSYDLAYQFLMAQEDVRINASPSVVTMNQTPARIAIV
EEMSIAVSADKEKAQYNRAQYGIMIKMLPVINVGEEDGKSYITLETDITFDTTGKNTNERPDVTRRNITNKVRIPDGETV
IIGGLRCKHASDSQDGIPFLGEIPGIGKLFGMNSTSDSQTEMFVFITPKILDNPAEKKERQEEAILSSRPGENAEFRKAL
CAGEEAAKAAHKKLELISAIELPASQVEGLEYDGR
>Mature_755_residues
MRFLRHPLVYFFGLSSLACCTPGQALTISEKAASLENSKEFIDSSPGLASFNADMKEYNLQLKSLYEEAAALREAGCEDE
ARWKLLLSKLTDVKKQIKRMEDLWAAEIRERGENPDEYALWHHPETTIYNLVSDYGEDNVIYLVPQDIGSIKVSALSKFT
VPKEGFEECLLQLLSRLGIGMRQVSPWIKELYTTHKEGCGVAGVFSSRKDLDLLPPSSYIGYVLNSKNIDVRADQHILRK
FANLDTTHIDLFGGKLWVFGSVGEISELLKIYDFIQEDSVRQEYRVVPLTKIEASEMISILKAAFREDVTKEGDEEGLGL
KVVPLQNQGRSLFLSGTAALVRQAVDLIKDLEEGIENPTDKTVFWYSVKHSDPQELAVLLSQVHDVFAGKDGGGVPSSSA
ESMLRDAASTIHIDTSSVGATKEGSVKYGNFIADSKTGTLIMVVEKEALPRIKMLLKKLDVPKKMVRIEVLLFERKLSSQ
RQAGLNLLRLGEEVCKKTSSAVSWTSSGILEFLFKGSTGSSLVPSYDLAYQFLMAQEDVRINASPSVVTMNQTPARIAIV
EEMSIAVSADKEKAQYNRAQYGIMIKMLPVINVGEEDGKSYITLETDITFDTTGKNTNERPDVTRRNITNKVRIPDGETV
IIGGLRCKHASDSQDGIPFLGEIPGIGKLFGMNSTSDSQTEMFVFITPKILDNPAEKKERQEEAILSSRPGENAEFRKAL
CAGEEAAKAAHKKLELISAIELPASQVEGLEYDGR

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=462, Percent_Identity=22.5108225108225, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789793, Length=280, Percent_Identity=23.5714285714286, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR013356
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 83639; Mature: 83639

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLRHPLVYFFGLSSLACCTPGQALTISEKAASLENSKEFIDSSPGLASFNADMKEYNL
CCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHH
QLKSLYEEAAALREAGCEDEARWKLLLSKLTDVKKQIKRMEDLWAAEIRERGENPDEYAL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
WHHPETTIYNLVSDYGEDNVIYLVPQDIGSIKVSALSKFTVPKEGFEECLLQLLSRLGIG
EECCCHHHHHHHHHCCCCCEEEEECCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHCCC
MRQVSPWIKELYTTHKEGCGVAGVFSSRKDLDLLPPSSYIGYVLNSKNIDVRADQHILRK
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHEEEEECCCCCEEHHHHHHHH
FANLDTTHIDLFGGKLWVFGSVGEISELLKIYDFIQEDSVRQEYRVVPLTKIEASEMISI
HHCCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHCCCHHHHEEECCEEECCHHHHHHH
LKAAFREDVTKEGDEEGLGLKVVPLQNQGRSLFLSGTAALVRQAVDLIKDLEEGIENPTD
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCC
KTVFWYSVKHSDPQELAVLLSQVHDVFAGKDGGGVPSSSAESMLRDAASTIHIDTSSVGA
CEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCCC
TKEGSVKYGNFIADSKTGTLIMVVEKEALPRIKMLLKKLDVPKKMVRIEVLLFERKLSSQ
CCCCCEEECCEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RQAGLNLLRLGEEVCKKTSSAVSWTSSGILEFLFKGSTGSSLVPSYDLAYQFLMAQEDVR
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEE
INASPSVVTMNQTPARIAIVEEMSIAVSADKEKAQYNRAQYGIMIKMLPVINVGEEDGKS
ECCCCCEEEECCCCCEEEEEEEEEEEEECCHHHHHHHHHHHCEEEEEECEEECCCCCCCE
YITLETDITFDTTGKNTNERPDVTRRNITNKVRIPDGETVIIGGLRCKHASDSQDGIPFL
EEEEEECEEEECCCCCCCCCCCCHHHCCCCEEECCCCCEEEEECEEECCCCCCCCCCCCC
GEIPGIGKLFGMNSTSDSQTEMFVFITPKILDNPAEKKERQEEAILSSRPGENAEFRKAL
CCCCCCCCEECCCCCCCCCCEEEEEECHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
CAGEEAAKAAHKKLELISAIELPASQVEGLEYDGR
HCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure
MRFLRHPLVYFFGLSSLACCTPGQALTISEKAASLENSKEFIDSSPGLASFNADMKEYNL
CCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHH
QLKSLYEEAAALREAGCEDEARWKLLLSKLTDVKKQIKRMEDLWAAEIRERGENPDEYAL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
WHHPETTIYNLVSDYGEDNVIYLVPQDIGSIKVSALSKFTVPKEGFEECLLQLLSRLGIG
EECCCHHHHHHHHHCCCCCEEEEECCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHCCC
MRQVSPWIKELYTTHKEGCGVAGVFSSRKDLDLLPPSSYIGYVLNSKNIDVRADQHILRK
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHEEEEECCCCCEEHHHHHHHH
FANLDTTHIDLFGGKLWVFGSVGEISELLKIYDFIQEDSVRQEYRVVPLTKIEASEMISI
HHCCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHCCCHHHHEEECCEEECCHHHHHHH
LKAAFREDVTKEGDEEGLGLKVVPLQNQGRSLFLSGTAALVRQAVDLIKDLEEGIENPTD
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCC
KTVFWYSVKHSDPQELAVLLSQVHDVFAGKDGGGVPSSSAESMLRDAASTIHIDTSSVGA
CEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCCC
TKEGSVKYGNFIADSKTGTLIMVVEKEALPRIKMLLKKLDVPKKMVRIEVLLFERKLSSQ
CCCCCEEECCEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RQAGLNLLRLGEEVCKKTSSAVSWTSSGILEFLFKGSTGSSLVPSYDLAYQFLMAQEDVR
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEE
INASPSVVTMNQTPARIAIVEEMSIAVSADKEKAQYNRAQYGIMIKMLPVINVGEEDGKS
ECCCCCEEEECCCCCEEEEEEEEEEEEECCHHHHHHHHHHHCEEEEEECEEECCCCCCCE
YITLETDITFDTTGKNTNERPDVTRRNITNKVRIPDGETVIIGGLRCKHASDSQDGIPFL
EEEEEECEEEECCCCCCCCCCCCHHHCCCCEEECCCCCEEEEECEEECCCCCCCCCCCCC
GEIPGIGKLFGMNSTSDSQTEMFVFITPKILDNPAEKKERQEEAILSSRPGENAEFRKAL
CCCCCCCCEECCCCCCCCCCEEEEEECHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
CAGEEAAKAAHKKLELISAIELPASQVEGLEYDGR
HCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]