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The map label for this gene is sdhB [H]

Identifier: 89897853

GI number: 89897853

Start: 46888

End: 47679

Strand: Direct

Name: sdhB [H]

Synonym: CF0046

Alternate gene names: 89897853

Gene position: 46888-47679 (Clockwise)

Preceding gene: 89897852

Following gene: 89897855

Centisome position: 4.02

GC content: 41.04

Gene sequence:

>792_bases
ATGGATATTCCTGAAACTTTTATATTGAAAATTTACCGAGGAACTCCGGGAAAACAATATTGGGAAAGTTTTGAATTGGC
CTTACATCCAGGAGAGAATGTAATCAGTGCTCTTATGGAAATAGAAAAACGTCCAGTAAATACTCTAGGGGAAACAGTAA
ATCCCGTTGTCTGGGAACAGGGATGTTTGGAAGAGGTCTGCGGTTCTTGCTCATTATTAGTAAACGGAGTGCCTCGTCAG
GCATGTACAGCACTTATTGAAGAGTATATTAAAAAGACAGGATCACGTGAGATTATTTTAGCCCCACTAACGAAATTCCC
TTTAATTCGAGATCTCATTGTTGATCGATCGATCATGTTCGATAACTTACAAAAGATTCAAGGATGGGTAGCTGCCGATA
CTGACGGGGAGAACAACGGCGTGAAGGTGTCGCAAGAGGAGCAAGAGCTTATGTATGCCTTGTCTATGTGTATGACGTGC
GGGTGCTGCACGGAAGCCTGTCCCCAAATTAATGAGCATAATGATTTTATAGGTCCTGTAGCTATTGCTCAATCGCGTTT
GTTTAATACCTATCCTGGGGATAAACAGTCTAAAAAACGCTTACTCACGCTCATGGGCAACAAAGGTATAGAAGGTTGTG
GTCAAGCACATAATTGCGAGCGCGTATGTCCTAAAAAACTTCCCTTAACAGAAAGTATTTCTGCAATGGGAAGAGATGTG
GCCAAATACTCTTTAAAGTCTTTATTCCGTTCGATTTTCAAAAGAAAGAAAAAAGAGCGAGAGGAAGATTAG

Upstream 100 bases:

>100_bases
AGCCTTCACTGCGAGATTACACAAAATCTTCGACAGCAAAAATCGAACTTACCAATGTTCCTGAACTTATTCATCTGCCC
ATATAAATAGAGAGAGGACT

Downstream 100 bases:

>100_bases
AAGAAGCCCTTGGGCATGCGGCTGCGGTATCCTGGAGGAGGTGGCATGCCATAGTCTATAGGGTTGGCGTAGAGAGTCCA
GGGTTGAGACACAGATAGCA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDIPETFILKIYRGTPGKQYWESFELALHPGENVISALMEIEKRPVNTLGETVNPVVWEQGCLEEVCGSCSLLVNGVPRQ
ACTALIEEYIKKTGSREIILAPLTKFPLIRDLIVDRSIMFDNLQKIQGWVAADTDGENNGVKVSQEEQELMYALSMCMTC
GCCTEACPQINEHNDFIGPVAIAQSRLFNTYPGDKQSKKRLLTLMGNKGIEGCGQAHNCERVCPKKLPLTESISAMGRDV
AKYSLKSLFRSIFKRKKKEREED

Sequences:

>Translated_263_residues
MDIPETFILKIYRGTPGKQYWESFELALHPGENVISALMEIEKRPVNTLGETVNPVVWEQGCLEEVCGSCSLLVNGVPRQ
ACTALIEEYIKKTGSREIILAPLTKFPLIRDLIVDRSIMFDNLQKIQGWVAADTDGENNGVKVSQEEQELMYALSMCMTC
GCCTEACPQINEHNDFIGPVAIAQSRLFNTYPGDKQSKKRLLTLMGNKGIEGCGQAHNCERVCPKKLPLTESISAMGRDV
AKYSLKSLFRSIFKRKKKEREED
>Mature_263_residues
MDIPETFILKIYRGTPGKQYWESFELALHPGENVISALMEIEKRPVNTLGETVNPVVWEQGCLEEVCGSCSLLVNGVPRQ
ACTALIEEYIKKTGSREIILAPLTKFPLIRDLIVDRSIMFDNLQKIQGWVAADTDGENNGVKVSQEEQELMYALSMCMTC
GCCTEACPQINEHNDFIGPVAIAQSRLFNTYPGDKQSKKRLLTLMGNKGIEGCGQAHNCERVCPKKLPLTESISAMGRDV
AKYSLKSLFRSIFKRKKKEREED

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=251, Percent_Identity=26.6932270916335, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790596, Length=177, Percent_Identity=29.9435028248588, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786943, Length=189, Percent_Identity=30.6878306878307, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17533915, Length=235, Percent_Identity=25.1063829787234, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322987, Length=246, Percent_Identity=24.7967479674797, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643156, Length=266, Percent_Identity=26.6917293233083, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137106, Length=245, Percent_Identity=26.530612244898, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29498; Mature: 29498

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPETFILKIYRGTPGKQYWESFELALHPGENVISALMEIEKRPVNTLGETVNPVVWEQ
CCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHH
GCLEEVCGSCSLLVNGVPRQACTALIEEYIKKTGSREIILAPLTKFPLIRDLIVDRSIMF
HHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
DNLQKIQGWVAADTDGENNGVKVSQEEQELMYALSMCMTCGCCTEACPQINEHNDFIGPV
HHHHHHHCCCEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AIAQSRLFNTYPGDKQSKKRLLTLMGNKGIEGCGQAHNCERVCPKKLPLTESISAMGRDV
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHH
AKYSLKSLFRSIFKRKKKEREED
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIPETFILKIYRGTPGKQYWESFELALHPGENVISALMEIEKRPVNTLGETVNPVVWEQ
CCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHH
GCLEEVCGSCSLLVNGVPRQACTALIEEYIKKTGSREIILAPLTKFPLIRDLIVDRSIMF
HHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
DNLQKIQGWVAADTDGENNGVKVSQEEQELMYALSMCMTCGCCTEACPQINEHNDFIGPV
HHHHHHHCCCEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AIAQSRLFNTYPGDKQSKKRLLTLMGNKGIEGCGQAHNCERVCPKKLPLTESISAMGRDV
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHH
AKYSLKSLFRSIFKRKKKEREED
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]