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The map label for this gene is yabD [H]

Identifier: 89897850

GI number: 89897850

Start: 43197

End: 43997

Strand: Direct

Name: yabD [H]

Synonym: CF0043

Alternate gene names: 89897850

Gene position: 43197-43997 (Clockwise)

Preceding gene: 89897849

Following gene: 89897851

Centisome position: 3.7

GC content: 40.7

Gene sequence:

>801_bases
ATGAATTTAGCAGATGCTCATGTTCATCTTTCGGACGATGCCTTTGTTGAGGATGCTAATGATGTGATTCAACGTGCAAA
AAATGCGGGAATTTCTCTCCTTGTGAATGTCACTACAACTATTAACGAGCTAAATAAGTCTTTTGCTTATGCCGAAAGAT
TCTCAGATTTGCGTTTTTGTCATGTTGCGGGAACGCCTCCGCAAGATGCTCATATAGACATAGAAGAGCATTTTCACTAT
TTCCAAGGTTTTGCTCAGGCTGGGAAATTATCCGCTATTGGCGAGGTTGGCCTGGATTATTGTTTTGCTGAAGATGATAT
GGCGAAAGATCGCCAGAAAGAAGTCCTAAAGAGGTATTTATCCTTAGCTCTAGAATATGAGCTCCCCCTTGTTGTGCACT
GTAGAGGTGCTTTCGAGGATTTTTTCCATATGATAGATCAATATTATCATCATGACAAGCGTTCTTGCCCCGGCATGTTG
CATTGTTTTACAGGATCTTTAGAGGAAGCTCGGGAACTTCTTTCTCGAGGATGGTTCATCTCTATTAGCGGGATCGTTAC
GTTTAAAAATGCTCAGGATCTACGTTCTGTAGTTTCTCAGATTCCTTTAGAGCATTTGTTGATAGAAACTGATGCTCCTT
TTCTTTCTCCTACTCCTTATCGAGGAAAGAAAAATGAACCCGCTTATATTACACATACGATAGAAGCTATTGCTGATATT
CATGGTATGGACCCTCATGAACTTGCAGATATAGCCTGTAGCAATGTTGTGCGTTTTTTAGAGGGGCATAAAAAAGGGTA
G

Upstream 100 bases:

>100_bases
ATTAAGAAAAACTTCCCTCGAAGTCGATTCTTTTGAAGATATTTCATGAAGAAATGTATGATCATGGATTTTCTTATCCA
AATTTAAAAGGAGAAGATCC

Downstream 100 bases:

>100_bases
CCTGTCTTTGATTGTCTAGTAAAAATCACTTCACATAATTCTGATGAAGCTTTTATGGTCTCTAGAAAAAGGGTTTGTGA
AATAAAGGCTTACGATGAAT

Product: deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNLADAHVHLSDDAFVEDANDVIQRAKNAGISLLVNVTTTINELNKSFAYAERFSDLRFCHVAGTPPQDAHIDIEEHFHY
FQGFAQAGKLSAIGEVGLDYCFAEDDMAKDRQKEVLKRYLSLALEYELPLVVHCRGAFEDFFHMIDQYYHHDKRSCPGML
HCFTGSLEEARELLSRGWFISISGIVTFKNAQDLRSVVSQIPLEHLLIETDAPFLSPTPYRGKKNEPAYITHTIEAIADI
HGMDPHELADIACSNVVRFLEGHKKG

Sequences:

>Translated_266_residues
MNLADAHVHLSDDAFVEDANDVIQRAKNAGISLLVNVTTTINELNKSFAYAERFSDLRFCHVAGTPPQDAHIDIEEHFHY
FQGFAQAGKLSAIGEVGLDYCFAEDDMAKDRQKEVLKRYLSLALEYELPLVVHCRGAFEDFFHMIDQYYHHDKRSCPGML
HCFTGSLEEARELLSRGWFISISGIVTFKNAQDLRSVVSQIPLEHLLIETDAPFLSPTPYRGKKNEPAYITHTIEAIADI
HGMDPHELADIACSNVVRFLEGHKKG
>Mature_266_residues
MNLADAHVHLSDDAFVEDANDVIQRAKNAGISLLVNVTTTINELNKSFAYAERFSDLRFCHVAGTPPQDAHIDIEEHFHY
FQGFAQAGKLSAIGEVGLDYCFAEDDMAKDRQKEVLKRYLSLALEYELPLVVHCRGAFEDFFHMIDQYYHHDKRSCPGML
HCFTGSLEEARELLSRGWFISISGIVTFKNAQDLRSVVSQIPLEHLLIETDAPFLSPTPYRGKKNEPAYITHTIEAIADI
HGMDPHELADIACSNVVRFLEGHKKG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=270, Percent_Identity=30.7407407407407, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI110349730, Length=271, Percent_Identity=30.9963099630996, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=30.0724637681159, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226061614, Length=262, Percent_Identity=29.0076335877863, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=31.1965811965812, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI225903424, Length=157, Percent_Identity=32.484076433121, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI14042943, Length=272, Percent_Identity=25.3676470588235, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI225903439, Length=196, Percent_Identity=29.0816326530612, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787342, Length=264, Percent_Identity=34.0909090909091, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=32.9457364341085, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=27.5193798449612, Blast_Score=104, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=286, Percent_Identity=29.7202797202797, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=26.2962962962963, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543026, Length=196, Percent_Identity=27.0408163265306, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=27.4647887323944, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221330018, Length=281, Percent_Identity=26.3345195729537, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24586117, Length=281, Percent_Identity=26.3345195729537, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30006; Mature: 30006

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLADAHVHLSDDAFVEDANDVIQRAKNAGISLLVNVTTTINELNKSFAYAERFSDLRFC
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEE
HVAGTPPQDAHIDIEEHFHYFQGFAQAGKLSAIGEVGLDYCFAEDDMAKDRQKEVLKRYL
EECCCCCCCCEECHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
SLALEYELPLVVHCRGAFEDFFHMIDQYYHHDKRSCPGMLHCFTGSLEEARELLSRGWFI
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCHHHHHHHHHCCCEE
SISGIVTFKNAQDLRSVVSQIPLEHLLIETDAPFLSPTPYRGKKNEPAYITHTIEAIADI
EEEEEEEECCHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
HGMDPHELADIACSNVVRFLEGHKKG
CCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLADAHVHLSDDAFVEDANDVIQRAKNAGISLLVNVTTTINELNKSFAYAERFSDLRFC
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEE
HVAGTPPQDAHIDIEEHFHYFQGFAQAGKLSAIGEVGLDYCFAEDDMAKDRQKEVLKRYL
EECCCCCCCCEECHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
SLALEYELPLVVHCRGAFEDFFHMIDQYYHHDKRSCPGMLHCFTGSLEEARELLSRGWFI
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCHHHHHHHHHCCCEE
SISGIVTFKNAQDLRSVVSQIPLEHLLIETDAPFLSPTPYRGKKNEPAYITHTIEAIADI
EEEEEEEECCHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
HGMDPHELADIACSNVVRFLEGHKKG
CCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]