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The map label for this gene is kdpD [H]

Identifier: 89257130

GI number: 89257130

Start: 1811748

End: 1812761

Strand: Reverse

Name: kdpD [H]

Synonym: FTL_1879

Alternate gene names: 89257130

Gene position: 1812761-1811748 (Counterclockwise)

Preceding gene: 89257131

Following gene: 89257129

Centisome position: 95.61

GC content: 34.71

Gene sequence:

>1014_bases
ATGGATAATCAACAAAAAGTAGATGCACTGCTAAACCTAGCTAATAAAAGCCAAGAATCTAAAAAAGGTAAATTAAAAAT
CTTTCTTGGCTATGCTCCTGGTGTCGGTAAGAGTTATACGATGCTTAATAATGCTCGAGCTTTACAGAAAGATAACAAAG
ATGTTGTGGTTGGCTTACTTGTAAGTCATGGCAGAGCAGACACACAGGCATTACTAGAGGGGCTTGAGATTATGCCTCTT
AAAAAGGTAAATTATCGTGGTAGAGTGTTTGAAGAGCTAGATATAGATGCAATTAAAGCTAGAAAACCTGATGTTGTGAT
CGTTGATGAATTACCTCATTCGAATTTACCGACATCACGAAACAAAAAAAGGTATATCGATATTGAAGAACTTCTTGATG
AGGGCATTTCAGTTTATACAGCGATTAATATTCAACATATTGTTAGCTTATCTTATGAGGTTACACAACTTACTCAGGCT
AATGTTAATGAAATTGTTCCAAATGATTTTATTCAATCAGCTGATGAGCTTGTTGTAGTTGATGTAAGTCCAGAGGAACT
GATTAAAAGACTTAAACAAGGTAAAGTATATAAAAGTGATGCAATAGATAGAGCATTAGAAAGATATTTTCAATATACAA
ATCTAACCATCCTCAGAGATTATACTTTTAGGATGGCTGCAAACCATGTCGGTCAAGATATTCAGCAGTATAGGAAGCTT
TACCAACATGGTAGTGCTATACCAACTTCACCATATGTACTAGTATGCTGTGGCTATGATGAGGCGACTCCAAGTTTATT
ACGTAAAGGTAAGCTCTTAGCAACGACTTTAAACGCAAGACTAATAGCAGTTTTTGTACAAAAACCTAATAAAGTCGCAA
CTAAACTTAATTTTGGTGTTATTAGACGTTATAAAATGCTGGCAAGCAGTCTTGGATATAATATTGATCATATACTTGGT
GATAGGCTTTCAGATAGTATAATTAGAGTACGCAAAATCAATAGGTGCAACTGA

Upstream 100 bases:

>100_bases
ACAACTATTAATCATAAGTAACTGATTAGTCAGTTTTCTGTTATAATTTTACTCTCAAGATGTTTTTCGTTGTTTGTAAA
AAATTCTTATTGAGGTTTCA

Downstream 100 bases:

>100_bases
TTTAGTAATCGGTAAATCGATACGACCAAAATGGAAAGATAAACTTTTTGGTTCTGTTGTCTACGATATTATCCGTAATA
ATAACAATGGTATGCAAGTA

Product: osmosensitive K+ channel His kinase sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDNQQKVDALLNLANKSQESKKGKLKIFLGYAPGVGKSYTMLNNARALQKDNKDVVVGLLVSHGRADTQALLEGLEIMPL
KKVNYRGRVFEELDIDAIKARKPDVVIVDELPHSNLPTSRNKKRYIDIEELLDEGISVYTAINIQHIVSLSYEVTQLTQA
NVNEIVPNDFIQSADELVVVDVSPEELIKRLKQGKVYKSDAIDRALERYFQYTNLTILRDYTFRMAANHVGQDIQQYRKL
YQHGSAIPTSPYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNKVATKLNFGVIRRYKMLASSLGYNIDHILG
DRLSDSIIRVRKINRCN

Sequences:

>Translated_337_residues
MDNQQKVDALLNLANKSQESKKGKLKIFLGYAPGVGKSYTMLNNARALQKDNKDVVVGLLVSHGRADTQALLEGLEIMPL
KKVNYRGRVFEELDIDAIKARKPDVVIVDELPHSNLPTSRNKKRYIDIEELLDEGISVYTAINIQHIVSLSYEVTQLTQA
NVNEIVPNDFIQSADELVVVDVSPEELIKRLKQGKVYKSDAIDRALERYFQYTNLTILRDYTFRMAANHVGQDIQQYRKL
YQHGSAIPTSPYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNKVATKLNFGVIRRYKMLASSLGYNIDHILG
DRLSDSIIRVRKINRCN
>Mature_337_residues
MDNQQKVDALLNLANKSQESKKGKLKIFLGYAPGVGKSYTMLNNARALQKDNKDVVVGLLVSHGRADTQALLEGLEIMPL
KKVNYRGRVFEELDIDAIKARKPDVVIVDELPHSNLPTSRNKKRYIDIEELLDEGISVYTAINIQHIVSLSYEVTQLTQA
NVNEIVPNDFIQSADELVVVDVSPEELIKRLKQGKVYKSDAIDRALERYFQYTNLTILRDYTFRMAANHVGQDIQQYRKL
YQHGSAIPTSPYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNKVATKLNFGVIRRYKMLASSLGYNIDHILG
DRLSDSIIRVRKINRCN

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=277, Percent_Identity=41.5162454873646, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38093; Mature: 38093

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQQKVDALLNLANKSQESKKGKLKIFLGYAPGVGKSYTMLNNARALQKDNKDVVVGLL
CCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEHHHCCHHHHCCCCCEEEEEE
VSHGRADTQALLEGLEIMPLKKVNYRGRVFEELDIDAIKARKPDVVIVDELPHSNLPTSR
ECCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCEEEEECCCCCCCCCCC
NKKRYIDIEELLDEGISVYTAINIQHIVSLSYEVTQLTQANVNEIVPNDFIQSADELVVV
CCCEEECHHHHHHCCCEEEEEECHHHHHHCCHHHHHHHHCCHHHCCCCHHHCCCCCEEEE
DVSPEELIKRLKQGKVYKSDAIDRALERYFQYTNLTILRDYTFRMAANHVGQDIQQYRKL
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHH
YQHGSAIPTSPYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNKVATKLNFGV
HHCCCCCCCCCEEEEEECCCCCCHHHHHCCCEEEEECCCEEEEEEEECCCHHHHHHHHHH
IRRYKMLASSLGYNIDHILGDRLSDSIIRVRKINRCN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDNQQKVDALLNLANKSQESKKGKLKIFLGYAPGVGKSYTMLNNARALQKDNKDVVVGLL
CCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEHHHCCHHHHCCCCCEEEEEE
VSHGRADTQALLEGLEIMPLKKVNYRGRVFEELDIDAIKARKPDVVIVDELPHSNLPTSR
ECCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCEEEEECCCCCCCCCCC
NKKRYIDIEELLDEGISVYTAINIQHIVSLSYEVTQLTQANVNEIVPNDFIQSADELVVV
CCCEEECHHHHHHCCCEEEEEECHHHHHHCCHHHHHHHHCCHHHCCCCHHHCCCCCEEEE
DVSPEELIKRLKQGKVYKSDAIDRALERYFQYTNLTILRDYTFRMAANHVGQDIQQYRKL
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHH
YQHGSAIPTSPYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNKVATKLNFGV
HHCCCCCCCCCEEEEEECCCCCCHHHHHCCCEEEEECCCEEEEEEEECCCHHHHHHHHHH
IRRYKMLASSLGYNIDHILGDRLSDSIIRVRKINRCN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]