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The map label for this gene is rppH

Identifier: 89256998

GI number: 89256998

Start: 1660661

End: 1661128

Strand: Reverse

Name: rppH

Synonym: FTL_1729

Alternate gene names: 89256998

Gene position: 1661128-1660661 (Counterclockwise)

Preceding gene: 89257001

Following gene: 89256996

Centisome position: 87.61

GC content: 36.11

Gene sequence:

>468_bases
ATGATAGATAAAAGTGGGTATCGAGCAAATGTAGCGATAGTTTTACTTAACAAGCAAAATAGAGTATTTTGGGGACAGCG
AAGAAACCGCACATCTTGGCAGTTTCCACAAGGTGGTGTAGCTACTGGAGAAACACCTTTGCAGGCAATGTATCGTGAGC
TACATGAGGAGATTGGCTTGCGTCCACAAGATGTTGAGGTAATCGCTTCAACAAGAGATTGGTATAAATATGATATTCCA
GACTCATTAGTTAGAACTAAAGAACCTATATGTATTGGTCAAAAACAGAAATGGTTTCTATTAAAATTAAAGAGTCCTGA
AAGTTATATTGATTTAGACGCTAATGACTCACCTGAATTTGATAATTGGCGTTGGGTAAGTTATTGGTATCCAATCAATC
ATGTAGTGTATTTCAAACAAGAGGTTTATCGTAAGGCTTTGACTTATTTTAAGGAGTATATAGCTTAA

Upstream 100 bases:

>100_bases
AACTTTTAGCTATTTTTTATTATCTATTATAAATGAATATAAAACTAAGAGGAATTAGTTTAGAATAAATAACTAGGTAT
AAGAAAGTTTTCTTTGAATA

Downstream 100 bases:

>100_bases
CAAGCTTTATTATTTGCTCTCTACAAAAACTTTAGACCATAAATATGTAAATATTCCTATATATGCAGCAACGATAACAT
CGGAAATAAAGTGATCTAAA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGLRPQDVEVIASTRDWYKYDIP
DSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEFDNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA

Sequences:

>Translated_155_residues
MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGLRPQDVEVIASTRDWYKYDIP
DSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEFDNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA
>Mature_155_residues
MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGLRPQDVEVIASTRDWYKYDIP
DSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEFDNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=155, Percent_Identity=54.1935483870968, Blast_Score=187, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_FRAT1 (Q14JR9)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666357.1
- ProteinModelPortal:   Q14JR9
- SMR:   Q14JR9
- STRING:   Q14JR9
- GeneID:   4200244
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0160
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- PhylomeDB:   Q14JR9
- ProtClustDB:   PRK00714
- BioCyc:   FTUL393115:FTF0160-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 18561; Mature: 18561

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGL
CCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
RPQDVEVIASTRDWYKYDIPDSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEF
CCCCEEEEECCCCCEEECCCHHHHHCCCCEEECCCCCEEEEEECCCCCEEEECCCCCCCC
DNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA
CCEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGL
CCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
RPQDVEVIASTRDWYKYDIPDSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEF
CCCCEEEEECCCCCEEECCCHHHHHCCCCEEECCCCCEEEEEECCCCCEEEECCCCCCCC
DNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA
CCEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA