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The map label for this gene is lptD [H]

Identifier: 89256673

GI number: 89256673

Start: 1306861

End: 1308687

Strand: Direct

Name: lptD [H]

Synonym: FTL_1374

Alternate gene names: 89256673

Gene position: 1306861-1308687 (Clockwise)

Preceding gene: 89256672

Following gene: 89256674

Centisome position: 68.93

GC content: 31.86

Gene sequence:

>1827_bases
ATGTTATATATAAAAAATGGATTTTTAAAGATTAAAGATATTCCTGTGATGTATCTACCGTACTATTCACATCCAACAAG
TAATAAAAGAAGATCAGGCTTCTTGAACCTTAATTTTGTCCAAAATCAAAGATCTGGCTGGGGTGTATCTATACCATATT
ATTTTAATCTTGCGGCTAATTATGACCTTTTATTACAAACTGTTATATGGTCTGAGAGAGGAATAATGGAAAATGCTACT
TTACGTTATATGGATAAATATTTCCAAAGTCAGTTTGAGGGCTCGATAGTTCCTTATGACTTTAAAGAAGGAAAAATACG
CGGTGCATTTACTTTATCAACTACAGCACAATATGAGAATATAAATGCCAACTTTAAATATGAATATGTTAGTGATGCAA
CATACTATGATGATTTTTCAGCTGGAGATATAAATCTAGTGACAAAGACATTATTGGATAGGCAATTAGGTATAAGCTAT
AATAATAGTTACGTTGACTTTGGTATTACGTTGTTAGATTATGGCATTGTAAACCCGATCATCAATCTAGCAAATATACC
TTATGCTAAACTGCCAGAGGTAAAATTTAATCTTACATCAGCAGGGTATACACCAGATTATCTGACACTTAGTCTAAATA
CCTTAAATACTTATTTTTACAAATCACCCTGGCCAGTAAATCCAAGTGTAGCCCCTACAGTTGGAACTAATGTTAATACT
TTTAGATTTTATGAGGCGCCTAAAATAGAACTAAATCTCACTAAAAGTTGGGGATATATAAAACCTTCATTAGAATTACC
TATACGTTACTATAAGCTTAATAATAAGCCTACAGATATTATTAAGTTTAAAAATAGTAATGTTACTAGTGTACTACCAA
TATTTAATATTGACGCTGGGGCATATTTTGATAAAGATTATACTAATGAAAATGGGACGTATACATCAACCTTACATCCT
AGACTATTCTATACTTACATACCGTACCAAGATCAAACAAATATACCATTATTTGATACAAGTTTACAAAATGAACAATA
TATGCAGATGTTTCAAGTAAATAGATTTACTGGTTATGATAGAATAAACAATGCTAATCAGCTAACATATGCGATAGAAG
CTTCAACAACTAATCAAGATAATGGTACTACTTTAGCGTCTGCTAAAATTGGTCAGATGGCTTATTTTGCTGATAGGAAA
GTTAATTTGTGTCAAGGAAATTCTGCTTGTCCGAATCCGGGTTTAATGGATCCTTTTTCAACAGATACTTTCTCTCCAAT
TATGAGCTCATTTGAGTTTCAAGTAATGAAAAATATTTACTTATCAGCTCAAGTGAATTATAGGGTTAAGCAACAAAACG
TTGACTATCAAGTCTATCAATTGTCATATAAAGATGAAAATGAGAATATTTTTAACGTTTCATATAATAATATTGCAAAT
AACTGGAACTCATTAACTCAACAGCAAATAGCAGAAGGTGCTAAGCCTCAACCACAAGAAACTATTACTCTTTCTACAGT
GTTAAATATTACTGATCATTGGGGTATTGCAGCGCTATGGAACTATAATTTCCAGCAAAAACAAATAGCTAATATATTTG
CAGGGCTGCAATACAATGCCAAATCTTGGGCGGTTAGAGCATTATGGCAGAAGACCGCGTATACTAACCAAGATCCTAAT
AATCCTAATTTCCTCGGAAACTTAAATAGTACTTACATGTTAGAGTTTGAGTTTAAAGGTCTTGGTAGTGTTAATAATAA
TGGTAACTTATCATCACATTTGCAACAGATAAATGGCTATAAAATCGGTCAATGGGGGCAGAATTAA

Upstream 100 bases:

>100_bases
TGATTTGATTATCACTGATGGCTATATAACATCTAATGATCCATATGATAATAGTTGAAAAATAACGGGGGATTATATAA
ATATTGATATTGATAAGGAA

Downstream 100 bases:

>100_bases
TAATATAAAAAGCTTTTGAATTAATATCCCAAATTTATACTAAATTTTCTAAAGTATAAATATCGTAGATGCTTGTATCT
TAGTGATTATGAATTTTTTC

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MLYIKNGFLKIKDIPVMYLPYYSHPTSNKRRSGFLNLNFVQNQRSGWGVSIPYYFNLAANYDLLLQTVIWSERGIMENAT
LRYMDKYFQSQFEGSIVPYDFKEGKIRGAFTLSTTAQYENINANFKYEYVSDATYYDDFSAGDINLVTKTLLDRQLGISY
NNSYVDFGITLLDYGIVNPIINLANIPYAKLPEVKFNLTSAGYTPDYLTLSLNTLNTYFYKSPWPVNPSVAPTVGTNVNT
FRFYEAPKIELNLTKSWGYIKPSLELPIRYYKLNNKPTDIIKFKNSNVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHP
RLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRK
VNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIAN
NWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPN
NPNFLGNLNSTYMLEFEFKGLGSVNNNGNLSSHLQQINGYKIGQWGQN

Sequences:

>Translated_608_residues
MLYIKNGFLKIKDIPVMYLPYYSHPTSNKRRSGFLNLNFVQNQRSGWGVSIPYYFNLAANYDLLLQTVIWSERGIMENAT
LRYMDKYFQSQFEGSIVPYDFKEGKIRGAFTLSTTAQYENINANFKYEYVSDATYYDDFSAGDINLVTKTLLDRQLGISY
NNSYVDFGITLLDYGIVNPIINLANIPYAKLPEVKFNLTSAGYTPDYLTLSLNTLNTYFYKSPWPVNPSVAPTVGTNVNT
FRFYEAPKIELNLTKSWGYIKPSLELPIRYYKLNNKPTDIIKFKNSNVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHP
RLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRK
VNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIAN
NWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPN
NPNFLGNLNSTYMLEFEFKGLGSVNNNGNLSSHLQQINGYKIGQWGQN
>Mature_608_residues
MLYIKNGFLKIKDIPVMYLPYYSHPTSNKRRSGFLNLNFVQNQRSGWGVSIPYYFNLAANYDLLLQTVIWSERGIMENAT
LRYMDKYFQSQFEGSIVPYDFKEGKIRGAFTLSTTAQYENINANFKYEYVSDATYYDDFSAGDINLVTKTLLDRQLGISY
NNSYVDFGITLLDYGIVNPIINLANIPYAKLPEVKFNLTSAGYTPDYLTLSLNTLNTYFYKSPWPVNPSVAPTVGTNVNT
FRFYEAPKIELNLTKSWGYIKPSLELPIRYYKLNNKPTDIIKFKNSNVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHP
RLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRK
VNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIAN
NWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPN
NPNFLGNLNSTYMLEFEFKGLGSVNNNGNLSSHLQQINGYKIGQWGQN

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=574, Percent_Identity=23.3449477351916, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 69779; Mature: 69779

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYIKNGFLKIKDIPVMYLPYYSHPTSNKRRSGFLNLNFVQNQRSGWGVSIPYYFNLAAN
CEEEECCCEEEECCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCEEECCEEEEEECC
YDLLLQTVIWSERGIMENATLRYMDKYFQSQFEGSIVPYDFKEGKIRGAFTLSTTAQYEN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEEEEEEEECC
INANFKYEYVSDATYYDDFSAGDINLVTKTLLDRQLGISYNNSYVDFGITLLDYGIVNPI
CCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHCCEECCCEEEEEHEEHHHHHHHHH
INLANIPYAKLPEVKFNLTSAGYTPDYLTLSLNTLNTYFYKSPWPVNPSVAPTVGTNVNT
HHHHCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCE
FRFYEAPKIELNLTKSWGYIKPSLELPIRYYKLNNKPTDIIKFKNSNVTSVLPIFNIDAG
EEEEECCEEEEEEECCCCEECCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEEEECCCC
AYFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYD
CEECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCC
RINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFS
CCCCCCEEEEEEEECCCCCCCCCEEEECCCCCEEEEECCEEEEECCCCCCCCCCCCCCCC
TDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIAN
CCHHHHHHHHHHHHEECCEEEEEEEEEEEECCCCCEEEEEEEEECCCCCEEEEEHHHHHC
NWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNA
CHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCEECC
KSWAVRALWQKTAYTNQDPNNPNFLGNLNSTYMLEFEFKGLGSVNNNGNLSSHLQQINGY
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCE
KIGQWGQN
ECCCCCCC
>Mature Secondary Structure
MLYIKNGFLKIKDIPVMYLPYYSHPTSNKRRSGFLNLNFVQNQRSGWGVSIPYYFNLAAN
CEEEECCCEEEECCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCEEECCEEEEEECC
YDLLLQTVIWSERGIMENATLRYMDKYFQSQFEGSIVPYDFKEGKIRGAFTLSTTAQYEN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEEEEEEEECC
INANFKYEYVSDATYYDDFSAGDINLVTKTLLDRQLGISYNNSYVDFGITLLDYGIVNPI
CCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHCCEECCCEEEEEHEEHHHHHHHHH
INLANIPYAKLPEVKFNLTSAGYTPDYLTLSLNTLNTYFYKSPWPVNPSVAPTVGTNVNT
HHHHCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCE
FRFYEAPKIELNLTKSWGYIKPSLELPIRYYKLNNKPTDIIKFKNSNVTSVLPIFNIDAG
EEEEECCEEEEEEECCCCEECCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEEEECCCC
AYFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYD
CEECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCC
RINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFS
CCCCCCEEEEEEEECCCCCCCCCEEEECCCCCEEEEECCEEEEECCCCCCCCCCCCCCCC
TDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIAN
CCHHHHHHHHHHHHEECCEEEEEEEEEEEECCCCCEEEEEEEEECCCCCEEEEEHHHHHC
NWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNA
CHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCEECC
KSWAVRALWQKTAYTNQDPNNPNFLGNLNSTYMLEFEFKGLGSVNNNGNLSSHLQQINGY
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCE
KIGQWGQN
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA