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The map label for this gene is pgsA [H]

Identifier: 89255665

GI number: 89255665

Start: 230224

End: 230820

Strand: Direct

Name: pgsA [H]

Synonym: FTL_0231

Alternate gene names: 89255665

Gene position: 230224-230820 (Clockwise)

Preceding gene: 89255664

Following gene: 89255666

Centisome position: 12.14

GC content: 34.51

Gene sequence:

>597_bases
ATGTTTTTTAATATCCCTAATATTCTGACTTTTGGTCGTTTGATATTAATTCCTTTTATAGTTATATGTTATTATTTTGA
GTTTCCACACCATCATGGTATTACGGCGACTTTATTTTTACTTGGGGCAGCAACTGATTGGTTGGATGGTTATTTGGCAC
GTAAATGGAAGCAAACTAGTAAGCTAGGTGCATTTTTAGATCCTGTTGCGGATAAGCTTATTGTTGCTACGGCGCTTTGT
TTGTTTATAGAGATGTATCCATATTGGTGGGCAACAATACCTGCTATTGTGATGATTTGTAGAGAAATTGTTGTTTCAGC
TTTGCGTGAATGGATGGCTGAACTCGGTCAGCGTAGTGTTGTTAAGGTTGGTGTTTGGGGTAAAGTGAAGACTGCAGCAC
AAATGGCAGCATTATTTATATTTTTAATCAAACCAGCTATAGATTTTAGACATTCTATAGACTATACGAGTTTCAATACT
TGGTTTATATTCTTAGGTTTCTTAATGCTTTATGTTGCAGTTATACTAACTATTTATTCTATGTGTAACTATCTCTATGT
GGCTTTTAAATCAGTTTTTGGTGCTTCTGATAACTAA

Upstream 100 bases:

>100_bases
AATTGTTCCTGTGGTACAAGCAAATTTTGAGATTGTTGAAGATTTTTCACAGCAAAGTGTCCGAGCTACTGGCGGCTTTG
GACATACAGGGGTTTGATTT

Downstream 100 bases:

>100_bases
TTAGTTTTTCTTTGCTTTTCTTTGCTTTTTTGATATTATTATTGTCTAATGCTATTTTTGCATAGCAAATGCTCTTATTG
AGTGTTTGGATTAATTTGAT

Product: phosphatidylglycerophosphate synthetase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MFFNIPNILTFGRLILIPFIVICYYFEFPHHHGITATLFLLGAATDWLDGYLARKWKQTSKLGAFLDPVADKLIVATALC
LFIEMYPYWWATIPAIVMICREIVVSALREWMAELGQRSVVKVGVWGKVKTAAQMAALFIFLIKPAIDFRHSIDYTSFNT
WFIFLGFLMLYVAVILTIYSMCNYLYVAFKSVFGASDN

Sequences:

>Translated_198_residues
MFFNIPNILTFGRLILIPFIVICYYFEFPHHHGITATLFLLGAATDWLDGYLARKWKQTSKLGAFLDPVADKLIVATALC
LFIEMYPYWWATIPAIVMICREIVVSALREWMAELGQRSVVKVGVWGKVKTAAQMAALFIFLIKPAIDFRHSIDYTSFNT
WFIFLGFLMLYVAVILTIYSMCNYLYVAFKSVFGASDN
>Mature_198_residues
MFFNIPNILTFGRLILIPFIVICYYFEFPHHHGITATLFLLGAATDWLDGYLARKWKQTSKLGAFLDPVADKLIVATALC
LFIEMYPYWWATIPAIVMICREIVVSALREWMAELGQRSVVKVGVWGKVKTAAQMAALFIFLIKPAIDFRHSIDYTSFNT
WFIFLGFLMLYVAVILTIYSMCNYLYVAFKSVFGASDN

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=188, Percent_Identity=49.468085106383, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22699; Mature: 22699

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFNIPNILTFGRLILIPFIVICYYFEFPHHHGITATLFLLGAATDWLDGYLARKWKQTS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLGAFLDPVADKLIVATALCLFIEMYPYWWATIPAIVMICREIVVSALREWMAELGQRSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VKVGVWGKVKTAAQMAALFIFLIKPAIDFRHSIDYTSFNTWFIFLGFLMLYVAVILTIYS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MCNYLYVAFKSVFGASDN
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFFNIPNILTFGRLILIPFIVICYYFEFPHHHGITATLFLLGAATDWLDGYLARKWKQTS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLGAFLDPVADKLIVATALCLFIEMYPYWWATIPAIVMICREIVVSALREWMAELGQRSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VKVGVWGKVKTAAQMAALFIFLIKPAIDFRHSIDYTSFNTWFIFLGFLMLYVAVILTIYS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MCNYLYVAFKSVFGASDN
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]