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The map label for this gene is cdsA [H]

Identifier: 89255663

GI number: 89255663

Start: 228970

End: 229764

Strand: Direct

Name: cdsA [H]

Synonym: FTL_0229

Alternate gene names: 89255663

Gene position: 228970-229764 (Clockwise)

Preceding gene: 89255662

Following gene: 89255664

Centisome position: 12.08

GC content: 32.83

Gene sequence:

>795_bases
ATGAAAGAAAGGATTGTGACTGGTATAGTTTTGGTCGCTGTGGTTTTTGGTTTTTTATTTTTTGCTTCTGACTATCTGTT
TGGTGTTGGTGTATTTTTAGTTACTTTAGTATCAGCGTATGAATGGTTGAAACTTGCAAAAATTGATCAGCAGTCAATAT
TTAAAAATCTTATTATATTTACGATAGTAGTTTTTGTGGTTGCACAGTTTTTTATATATCTTCAATATATATTCCCAATA
TTTTGGTTGTATGCGATCTATAAATTAGCTAGTTATGAGCGTCAGAAAATCGATGCAATAGCAACTAATGAAATGCTTGT
GATGGGAGTATTTACTATATCTCCTTTTGCTGCATCATTATATATACTACATACTAATGGTGTTGCATGGATATTTATGT
TTATCTTGGTAATTGCCGCAGCTGATAGTGGAGCATATTTTACTGGCAAAGCTATTGGTAAACGTAAAATGTTACCACGA
CTAAGTCCAAATAAAACTATTGAAGGTTTATTGGGTGGTTTGATTTGTGCTGTTATTGTTGCAGTGATTTTTCTTGTTTA
TATGAATTTAAGTTTTGGACAGTATATTTATATGGTTATAGTATCTGCTTTAATTGCGTTGTTATCTGTTGTTGGTGATG
TTTTTGAGAGTATGATGAAGCGAATAGCTGGTGTCAAGGATAGTGGCAATATTTTACCTGGGCATGGTGGAGTGCTTGAT
AGGTTGGATGGATATATGCCAACTTTACCAATATTTGTGCTGTTTGGTTATTTAGCGGGAGTTTTTGTTTTTTAG

Upstream 100 bases:

>100_bases
GATTTTTCTAAGCAAGAATTAACTAGAGCTGTTGAGTATTTTTATTCTCGTCAAAGAAGATTTGGCAAAAGTGGTGAACA
AATTTAATTAAGAGGAATTT

Downstream 100 bases:

>100_bases
GGGGAAGATATGAAGGTAGAGCTAAAAATTTTAAATAAAGAACTTATAAAAGAGTTACCCGGTTATGCGACTGAAGGTTC
AGCAGCTATTGACTTAAGAG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKERIVTGIVLVAVVFGFLFFASDYLFGVGVFLVTLVSAYEWLKLAKIDQQSIFKNLIIFTIVVFVVAQFFIYLQYIFPI
FWLYAIYKLASYERQKIDAIATNEMLVMGVFTISPFAASLYILHTNGVAWIFMFILVIAAADSGAYFTGKAIGKRKMLPR
LSPNKTIEGLLGGLICAVIVAVIFLVYMNLSFGQYIYMVIVSALIALLSVVGDVFESMMKRIAGVKDSGNILPGHGGVLD
RLDGYMPTLPIFVLFGYLAGVFVF

Sequences:

>Translated_264_residues
MKERIVTGIVLVAVVFGFLFFASDYLFGVGVFLVTLVSAYEWLKLAKIDQQSIFKNLIIFTIVVFVVAQFFIYLQYIFPI
FWLYAIYKLASYERQKIDAIATNEMLVMGVFTISPFAASLYILHTNGVAWIFMFILVIAAADSGAYFTGKAIGKRKMLPR
LSPNKTIEGLLGGLICAVIVAVIFLVYMNLSFGQYIYMVIVSALIALLSVVGDVFESMMKRIAGVKDSGNILPGHGGVLD
RLDGYMPTLPIFVLFGYLAGVFVF
>Mature_264_residues
MKERIVTGIVLVAVVFGFLFFASDYLFGVGVFLVTLVSAYEWLKLAKIDQQSIFKNLIIFTIVVFVVAQFFIYLQYIFPI
FWLYAIYKLASYERQKIDAIATNEMLVMGVFTISPFAASLYILHTNGVAWIFMFILVIAAADSGAYFTGKAIGKRKMLPR
LSPNKTIEGLLGGLICAVIVAVIFLVYMNLSFGQYIYMVIVSALIALLSVVGDVFESMMKRIAGVKDSGNILPGHGGVLD
RLDGYMPTLPIFVLFGYLAGVFVF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=276, Percent_Identity=31.8840579710145, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787677, Length=155, Percent_Identity=38.0645161290323, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29329; Mature: 29329

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS01315 CDS ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]