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The map label for this gene is lpxP [H]

Identifier: 89255614

GI number: 89255614

Start: 181606

End: 182529

Strand: Direct

Name: lpxP [H]

Synonym: FTL_0180

Alternate gene names: 89255614

Gene position: 181606-182529 (Clockwise)

Preceding gene: 89255613

Following gene: 89255615

Centisome position: 9.58

GC content: 33.01

Gene sequence:

>924_bases
ATGAATAATAACAAGTTTAGTCCTAAAAACTGGGGTATCTGGATTGTCGTTGGTATAATGAACTGCGGCTCGAAGCTACC
TTTATTTACACATAAATATATAGTTTTAACTATTGGTCTTATTATTAAACCTTTTTTAAAAAGTCGTAATAATATCGCTT
ATGAGAACCTTAAGATAGCTTTTCCTGAGAAATCTAACAAAGAAATAAAAAAACTAGTCAAAAAAAGTTATTATTCAATG
GTGTTATCTGGAGCTGAAATAACCGCCGCATGGTTTCTCTCTAAAAAAAGATTTAATAAAATTGAGTTTAAATGGGAAGA
AGGCTCTAGGGAAAGATTCGAAAAATATCATAATGATCCTGATAAAAAACTAATTATCTTAGGTTTTCACTTTCATTGTA
TCGAGATCATCGGTAGATATATGGGGCAAGAGTTTCCGCCATTTACCGTAATGTATCAAAAAAATGGTAATGACCTTATA
GAAGACTTAAGTAAAGAATATCGCGAAAAAAACCTATATAAGTGTCTTGATAGCAAGAACTTTGTTTCTGTTATTAAAAG
CCTAAAAAAAGGCTATACAATGTGGTACGCTCCAGATCAGGACTTTGGTTTAGAAAGCACCGGCTTAGAAAATTCGGTAT
TTGCTCCTTTTTTTGGTAAACTATGCTCAACTTTAACTGTAACTCCTTGGCTTGCCCAAAAAACGGGAGCTATTGTAATA
CCTGCATATTATGTTAGAGAAAAGTGTCTAAAAAAATATAAAATAGTCACTGGAGAGCCTTTCGAGTTTACAGGTGACGC
CTATAAAGATGCTGAAATGACAAATAAATTCCTAGAAGATGCGGTAAGAAAATATCCAGAACAATATTTATGGCAGCATC
GTCGCTATAGAACCAGACCAAATAGTGAGCCACAAATATACTAA

Upstream 100 bases:

>100_bases
ATATAAAACAAGACCACTAGGTGAAGAAAAAATTTATTAGTATTTATGATTGTTAAAGTATATGTTAAAATGTCAATAGC
GTTTTAATGTTAAGAAGTAA

Downstream 100 bases:

>100_bases
GGCTTTTATTAAATGTTAGATAAAAAAGGTTTTTCTTTAGTTGAGTTAATAGTGGTAATAGCAATTATAGCTATTCTTGC
ATCTATAGGTATACCTATGT

Product: acyltransferase

Products: KDO2-(palmitoleoyl)-lipid IVA [C]

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNNNKFSPKNWGIWIVVGIMNCGSKLPLFTHKYIVLTIGLIIKPFLKSRNNIAYENLKIAFPEKSNKEIKKLVKKSYYSM
VLSGAEITAAWFLSKKRFNKIEFKWEEGSRERFEKYHNDPDKKLIILGFHFHCIEIIGRYMGQEFPPFTVMYQKNGNDLI
EDLSKEYREKNLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFGLESTGLENSVFAPFFGKLCSTLTVTPWLAQKTGAIVI
PAYYVREKCLKKYKIVTGEPFEFTGDAYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNSEPQIY

Sequences:

>Translated_307_residues
MNNNKFSPKNWGIWIVVGIMNCGSKLPLFTHKYIVLTIGLIIKPFLKSRNNIAYENLKIAFPEKSNKEIKKLVKKSYYSM
VLSGAEITAAWFLSKKRFNKIEFKWEEGSRERFEKYHNDPDKKLIILGFHFHCIEIIGRYMGQEFPPFTVMYQKNGNDLI
EDLSKEYREKNLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFGLESTGLENSVFAPFFGKLCSTLTVTPWLAQKTGAIVI
PAYYVREKCLKKYKIVTGEPFEFTGDAYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNSEPQIY
>Mature_307_residues
MNNNKFSPKNWGIWIVVGIMNCGSKLPLFTHKYIVLTIGLIIKPFLKSRNNIAYENLKIAFPEKSNKEIKKLVKKSYYSM
VLSGAEITAAWFLSKKRFNKIEFKWEEGSRERFEKYHNDPDKKLIILGFHFHCIEIIGRYMGQEFPPFTVMYQKNGNDLI
EDLSKEYREKNLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFGLESTGLENSVFAPFFGKLCSTLTVTPWLAQKTGAIVI
PAYYVREKCLKKYKIVTGEPFEFTGDAYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNSEPQIY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=302, Percent_Identity=30.4635761589404, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787292, Length=314, Percent_Identity=31.8471337579618, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788161, Length=304, Percent_Identity=25, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 36126; Mature: 36126

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNKFSPKNWGIWIVVGIMNCGSKLPLFTHKYIVLTIGLIIKPFLKSRNNIAYENLKIA
CCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEE
FPEKSNKEIKKLVKKSYYSMVLSGAEITAAWFLSKKRFNKIEFKWEEGSRERFEKYHNDP
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCC
DKKLIILGFHFHCIEIIGRYMGQEFPPFTVMYQKNGNDLIEDLSKEYREKNLYKCLDSKN
CCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCH
FVSVIKSLKKGYTMWYAPDQDFGLESTGLENSVFAPFFGKLCSTLTVTPWLAQKTGAIVI
HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCEEE
PAYYVREKCLKKYKIVTGEPFEFTGDAYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRP
CHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSEPQIY
CCCCCCC
>Mature Secondary Structure
MNNNKFSPKNWGIWIVVGIMNCGSKLPLFTHKYIVLTIGLIIKPFLKSRNNIAYENLKIA
CCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEE
FPEKSNKEIKKLVKKSYYSMVLSGAEITAAWFLSKKRFNKIEFKWEEGSRERFEKYHNDP
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCC
DKKLIILGFHFHCIEIIGRYMGQEFPPFTVMYQKNGNDLIEDLSKEYREKNLYKCLDSKN
CCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCH
FVSVIKSLKKGYTMWYAPDQDFGLESTGLENSVFAPFFGKLCSTLTVTPWLAQKTGAIVI
HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCEEE
PAYYVREKCLKKYKIVTGEPFEFTGDAYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRP
CHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSEPQIY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; palmitoleoyl-ACP [C]

Specific reaction: KDO2-lipid IVA + palmitoleoyl-ACP = KDO2-(palmitoleoyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]