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The map label for this gene is lpxP [H]

Identifier: 89255613

GI number: 89255613

Start: 180646

End: 181545

Strand: Direct

Name: lpxP [H]

Synonym: FTL_0179

Alternate gene names: 89255613

Gene position: 180646-181545 (Clockwise)

Preceding gene: 89255612

Following gene: 89255614

Centisome position: 9.53

GC content: 32.67

Gene sequence:

>900_bases
ATGGATAAATCTCTACTTAAACCAAAATATTGGGGTATATGGATTATAATTTGGATCGCCAAGTTTATAGTAAATATACT
TCCATACAAAATGCTAATGCGTCTTGCAATAGGCATTGGTTTTTTAGCAAAGCCTCTACTCAAAAAACGTCAACAAATAG
CAATTACCAATCTTAAGATCGCATTCCCTGAAAAATCAGATCAAGAAATAAAAAAACTAGTCGATGCTAGTTATAAATCA
GCTAGTATGGCTGGTTTTGAAAGTCTAATTTCTTGGTTCATGACTAAAAAGAACTTCAACAAAATTCCTTTTGATAACGA
TCTAAGATCATTTGATGAAATTCATTATGACAAAGACAAAACTCTACTAGTATTAGGTTTTCACTTTCATTGCCTTGAGA
TAGCTGGTCGCTATATTGGTGAGAACTATAGTCCGTTTACAGTAATGTATCAATACCATAATAATCCTCTGATGGAATAT
ATCATTACCTCATCACGCAAAAAGTATGTGACTGAATGCTTCCAAAGAAAAAATATAATCGCCGTTATCAAAAGTTTAAA
AAGAAAAGTCTCTATGTGGTATGCTCCAGATCAAGACTTTAGAGAACATGTAGTTTTTGCACCATTCTTTGGTAAGCTTT
GTACTACCCTAACCGTAACACCATGGTTAGCAGAAAAAACAAATGCTACTGTTATTCCAGCTTACTATGTCAGAAAGCCC
GATCTTTCCGGATATAGTATTATAACTGGAGAGCCAATAATATTTAGTGGTAATGATCTAGAAGATGCGAAACTAACAAA
TAAAATCCTTGAAGAAATAATTAAAAAACATCCTGAACAATATTTATGGCAGCATCGTCGATATAAAACAAGACCACTAG
GTGAAGAAAAAATTTATTAG

Upstream 100 bases:

>100_bases
TGGTCTAGTATTATATTGGCTGACGAATAACCTAATCAGTATTTCACAACAGTGGATTATTACAAGACACTATCAAGCTA
CTCATAAAAAATAAATATAC

Downstream 100 bases:

>100_bases
TATTTATGATTGTTAAAGTATATGTTAAAATGTCAATAGCGTTTTAATGTTAAGAAGTAAATGAATAATAACAAGTTTAG
TCCTAAAAACTGGGGTATCT

Product: acyltransferase

Products: KDO2-(palmitoleoyl)-lipid IVA [C]

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIGIGFLAKPLLKKRQQIAITNLKIAFPEKSDQEIKKLVDASYKS
ASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDKTLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEY
IITSSRKKYVTECFQRKNIIAVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY

Sequences:

>Translated_299_residues
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIGIGFLAKPLLKKRQQIAITNLKIAFPEKSDQEIKKLVDASYKS
ASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDKTLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEY
IITSSRKKYVTECFQRKNIIAVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY
>Mature_299_residues
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIGIGFLAKPLLKKRQQIAITNLKIAFPEKSDQEIKKLVDASYKS
ASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDKTLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEY
IITSSRKKYVTECFQRKNIIAVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=305, Percent_Identity=35.7377049180328, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787292, Length=302, Percent_Identity=34.7682119205298, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1788161, Length=303, Percent_Identity=24.7524752475248, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 35161; Mature: 35161

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIGIGFLAKPLLKKRQQIAITNLKI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
AFPEKSDQEIKKLVDASYKSASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDK
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
TLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEYIITSSRKKYVTECFQRKNII
EEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHCCCHH
AVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
HHHHHHHHHHHHCCCCCHHHHHHEEECHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEECC
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY
CCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIGIGFLAKPLLKKRQQIAITNLKI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
AFPEKSDQEIKKLVDASYKSASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDK
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
TLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEYIITSSRKKYVTECFQRKNII
EEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHCCCHH
AVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
HHHHHHHHHHHHCCCCCHHHHHHEEECHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEECC
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY
CCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; palmitoleoyl-ACP [C]

Specific reaction: KDO2-lipid IVA + palmitoleoyl-ACP = KDO2-(palmitoleoyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]